tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Thrombotic Microangiopathies D057049 1 associated lipids
Autoimmune Diseases of the Nervous System D020274 1 associated lipids
Lupus Erythematosus, Discoid D008179 1 associated lipids
Lymphocytic Choriomeningitis D008216 1 associated lipids
Erythroplasia D004919 1 associated lipids
Hepatic Veno-Occlusive Disease D006504 1 associated lipids
West Nile Fever D014901 1 associated lipids
Hypoalbuminemia D034141 1 associated lipids
Arm Injuries D001134 1 associated lipids
Intussusception D007443 1 associated lipids
Primary Graft Dysfunction D055031 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Epididymitis D004823 1 associated lipids
Pruritus Vulvae D011539 1 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Feline Acquired Immunodeficiency Syndrome D016181 1 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
AIDS-Associated Nephropathy D016263 1 associated lipids
Oral Ulcer D019226 1 associated lipids
Epidermolysis Bullosa Dystrophica D016108 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Waer M New immunosuppressive agents for organ transplantation. 1997 Acta Clin Belg pmid:9351290
Liang J et al. Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. 1999 Acta Crystallogr. D Biol. Crystallogr. pmid:10089303
Bracher A et al. Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. 2011 Acta Crystallogr. D Biol. Crystallogr. pmid:21636895
Li P et al. Structure of the N-terminal domain of human FKBP52. 2003 Acta Crystallogr. D Biol. Crystallogr. pmid:12499534
Schreier MH Immunophilins and immunosuppression by cyclosporins and macrolide structures. 1994 Acta Derm Venereol Suppl (Stockh) pmid:7521103
Segura S et al. Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. 2005 Acta Derm. Venereol. pmid:16396803
Mercader P et al. Treatment of protein contact dermatitis with topical tacrolimus. 2005 Acta Derm. Venereol. pmid:16396818
Bovenschen HJ Novel treatment for cheilitis glandularis. 2009 Acta Derm. Venereol. pmid:19197557
Hamade Y et al. Lichen planus in childhood showing various cutaneous features. 2012 Acta Derm. Venereol. pmid:22101991
Reitamo S et al. Long-term treatment with 0.1% tacrolimus ointment in adults with atopic dermatitis: results of a two-year, multicentre, non-comparative study. 2007 Acta Derm. Venereol. pmid:17721647
Benedix F et al. Response of ulcerated necrobiosis lipoidica to clofazimine. 2009 Acta Derm. Venereol. pmid:19997705
Halvorsen JA and Aasebø W Oral tacrolimus treatment of pruritus in prurigo nodularis. 2015 Acta Derm. Venereol. pmid:25804254
Honda Y et al. Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. 2015 Acta Derm. Venereol. pmid:25881714
Jensen JM et al. Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. 2013 Acta Derm. Venereol. pmid:23571785
Larsen CG and Thyssen JP Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. 2012 Acta Derm. Venereol. pmid:21681352
Ambo M Relapsing Kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis. 2002 Acta Derm. Venereol. pmid:12353724
Mrowietz U et al. An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. 2003 Acta Derm. Venereol. pmid:14609102
Pagliarello C et al. Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. 2012 Acta Derm. Venereol. pmid:22293917
Yamamoto T and Nishioka K Topical tacrolimus is effective for facial lesions of psoriasis. 2000 Nov-Dec Acta Derm. Venereol. pmid:11243645
Lee HY et al. Oral mucous membrane pemphigoid: complete response to topical tacrolimus. 2011 Acta Derm. Venereol. pmid:21597668