tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Cardiomyopathy, Restrictive D002313 1 associated lipids
Paraparesis, Tropical Spastic D015493 1 associated lipids
Neurodermatitis D009450 1 associated lipids
Posterior Leukoencephalopathy Syndrome D054038 1 associated lipids
Ecthyma, Contagious D004474 1 associated lipids
Priapism D011317 1 associated lipids
Vulvar Lichen Sclerosus D007724 1 associated lipids
Mediastinal Diseases D008477 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Leukemia, Myeloid, Chronic-Phase D015466 1 associated lipids
Myelinolysis, Central Pontine D017590 1 associated lipids
Protoporphyria, Erythropoietic D046351 1 associated lipids
Smooth Muscle Tumor D018235 1 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Ichthyosiform Erythroderma, Congenital D016113 1 associated lipids
Panniculitis, Lupus Erythematosus D015435 1 associated lipids
Retrognathia D063173 1 associated lipids
Lacerations D022125 1 associated lipids
Megacolon, Toxic D008532 1 associated lipids
Tinea Capitis D014006 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Varela E [Small bowel transplantation]. 1995 Acta Gastroenterol. Latinoam. pmid:7544939
Pirenne J Contribution of large animal models to the development of clinical intestinal transplantation. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427786
Jamieson NV Adult small intestinal transplantation in Europe. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427790
Bonaccorsi-Riani E et al. Impact of steroid-avoidance immunosuppression on long-term outcome after liver transplantation for HCV cirrhosis: the need for well documented long-term follow-up. 2012 Acta Gastroenterol. Belg. pmid:23402084
Reding R et al. Stepwise minimization of the immunosuppressive therapy in pediatric liver transplantation. A conceptual approach towards operational tolerance. 2005 Jul-Sep Acta Gastroenterol. Belg. pmid:16268418
Sato M et al. FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. 1993 Acta Endocrinol. pmid:7509103
Polastri L et al. Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells. 2002 Acta Diabetol pmid:12486498
Persić-Vojinović S et al. Disseminated Hailey-Hailey disease treated with topical tacrolimus and oral erythromycin: Case report and review of the literature. 2006 Acta Dermatovenerol Croat pmid:17311740
Louvain D et al. Lichen sclerosus in the oral mucosa: a rare form of presentation. 2012 Acta Dermatovenerol Croat pmid:22507475
Lipozencić J Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. 2005 Acta Dermatovenerol Croat pmid:15788149
Pustisek N et al. Tacrolimus ointment: a new therapy for atopic dermatitis--review of the literature. 2002 Acta Dermatovenerol Croat pmid:12137728
Jedlicková H et al. Granuloma faciale successfully treated with topical tacrolimus: a case report. 2008 Acta Dermatovenerol Alp Pannonica Adriat pmid:18454269
Thaçi D and Salgo R The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. 2007 Acta Dermatovenerol Alp Pannonica Adriat pmid:17992459
Vukićević J et al. Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. 2009 Acta Dermatovenerol Alp Pannonica Adriat pmid:19350187
Segura S et al. Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. 2005 Acta Derm. Venereol. pmid:16396803
Mercader P et al. Treatment of protein contact dermatitis with topical tacrolimus. 2005 Acta Derm. Venereol. pmid:16396818
Halvorsen JA and Aasebø W Oral tacrolimus treatment of pruritus in prurigo nodularis. 2015 Acta Derm. Venereol. pmid:25804254
Larsen CG and Thyssen JP Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. 2012 Acta Derm. Venereol. pmid:21681352
Remitz A et al. Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. 2007 Acta Derm. Venereol. pmid:17225017
Mrowietz U et al. An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. 2003 Acta Derm. Venereol. pmid:14609102