| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adrenal Insufficiency | D000309 | 3 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Albuminuria | D000419 | 18 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amenorrhea | D000568 | 4 associated lipids |
| Amputation, Traumatic | D000673 | 2 associated lipids |
| Anemia | D000740 | 21 associated lipids |
| Anemia, Aplastic | D000741 | 6 associated lipids |
| Anemia, Hemolytic | D000743 | 4 associated lipids |
| Anemia, Hemolytic, Autoimmune | D000744 | 5 associated lipids |
| Anemia, Refractory | D000753 | 3 associated lipids |
| Anemia, Refractory, with Excess of Blasts | D000754 | 2 associated lipids |
| Aneurysm, Dissecting | D000784 | 2 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hiraoka A et al. | Phase III study comparing tacrolimus (FK506) with cyclosporine for graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation. | 2001 | Bone Marrow Transplant. | pmid:11509936 |
| McAlister VC et al. | Orthotopic liver transplantation using low-dose tacrolimus and sirolimus. | 2001 | Liver Transpl. | pmid:11510015 |
| Terui T et al. | Production and pharmacologic modulation of the granulocyte-associated allergic responses to ovalbumin in murine skin models induced by injecting ovalbumin-specific Th1 or Th2 cells. | 2001 | J. Invest. Dermatol. | pmid:11511299 |
| Tatekawa Y et al. | Intragraft expression of p38 and activated p38 MAPK (mitogen-activated protein kinase) in rat small bowel transplantation. | 2001 | Transpl. Int. | pmid:11512052 |
| Hochleitner BW et al. | Increased tacrolimus levels during diarrhea. | 2001 | Transpl. Int. | pmid:11512055 |
| Marx SO and Marks AR | Bench to bedside: the development of rapamycin and its application to stent restenosis. | 2001 | Circulation | pmid:11514367 |
| Hiraga K et al. | A novel screening for inhibitors of a pleiotropic drug resistant pump, Pdr5, in Saccharomyces cerevisiae. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11515543 |
| Taupin JL et al. | Functional quantification of cyclosporine A and FK506 in human whole blood by flow cytometry, using the green fluorescent protein as an interleukin-2 reporter gene. | 2001 | J. Immunol. Methods | pmid:11516757 |
| Cole O et al. | The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model. | 2001 | Ann R Coll Surg Engl | pmid:11518369 |
| Suzuki K et al. | FK506 facilitates chemical kindling induced by pentylenetetrazole in rats. | 2001 | Epilepsy Res. | pmid:11518629 |
| Hashida T and Inui K | [Therapeutic drug monitoring of immunosuppresants]. | 2001 | Rinsho Byori | pmid:11519126 |
| Morioka M et al. | Intravenously injected FK506 failed to inhibit hippocampal calcineurin. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11520068 |
| Dmitrewski J et al. | Metabolic and hormonal effects of tacrolimus (FK506) or cyclosporin immunosuppression following renal transplantation. | 2001 | Diabetes Obes Metab | pmid:11520309 |
| Behrend M | Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management. | 2001 | Drug Saf | pmid:11522119 |
| Staatz C et al. | Low tacrolimus concentrations and increased risk of early acute rejection in adult renal transplantation. | 2001 | Nephrol. Dial. Transplant. | pmid:11522877 |
| Anneser JM et al. | Immunosuppressant FK506 does not exert beneficial effects in symptomatic G93A superoxide dismutase-1 transgenic mice. | 2001 | Neuroreport | pmid:11522944 |
| Lhoëst G et al. | In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry. | 2001 | J Mass Spectrom | pmid:11523088 |
| Szabo G et al. | Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells. | 2001 | J. Investig. Med. | pmid:11523700 |
| Abu-Elmagd K et al. | Clinical intestinal transplantation: a decade of experience at a single center. | 2001 | Ann. Surg. | pmid:11524593 |
| Riboldi-Tunnicliffe A et al. | Crystal structure of Mip, a prolylisomerase from Legionella pneumophila. | 2001 | Nat. Struct. Biol. | pmid:11524681 |
| Freyschmidt-Paul P et al. | Treatment of alopecia areata in C3H/HeJ mice with the topical immunosuppressant FK506 (Tacrolimus). | 2001 Sep-Oct | Eur J Dermatol | pmid:11525945 |
| Tremblay JP and Vilquin JT | [Transplantation of normal or genetically modified myoblasts for the treatment of hereditary or acquired diseases]. | 2001 | J. Soc. Biol. | pmid:11530497 |
| Ikegame K et al. | Lethal adenovirus infection in a patient who had undergone nonmyeloablative stem cell transplantation. | 2001 | Int. J. Hematol. | pmid:11530814 |
| Elinav H et al. | Plasma oxidizability and plasma carbonyls, markers of oxidative stress, in liver transplant patients. | 2001 | Transplant. Proc. | pmid:11543789 |
| Mor E et al. | Homocysteine levels among transplant recipients: effect of immunosuppressive protocols. | 2001 | Transplant. Proc. | pmid:11543802 |
| Weinbroum AA et al. | Lack of cumulative effect of tacrolimus and low flow on a rat isolated liver. | 2001 | Transplant. Proc. | pmid:11543812 |
| Kovalev GI et al. | An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. | 2001 | J. Immunol. | pmid:11544316 |
| Berg UB et al. | Renal function before and long after liver transplantation in children. | 2001 | Transplantation | pmid:11544422 |
| Aw MM et al. | Calcineurin-inhibitor related nephrotoxicity- reversibility in paediatric liver transplant recipients. | 2001 | Transplantation | pmid:11544444 |
| Mann J | Natural products as immunosuppressive agents. | 2001 | Nat Prod Rep | pmid:11548050 |
| Furukawa M et al. | MRI in seven cases of tacrolimus (FK-506) encephalopathy: utility of FLAIR and diffusion-weighted imaging. | 2001 | Neuroradiology | pmid:11548166 |
| Lübbe J | Topical tacrolimus for atopic dermatitis: euphoria and vigilance. | 2001 | Dermatology (Basel) | pmid:11549790 |
| Kawakami T et al. | Safe and effective treatment of refractory facial lesions in atopic dermatitis using topical tacrolimus following corticosteroid discontinuation. | 2001 | Dermatology (Basel) | pmid:11549797 |
| Aker S et al. | Different effects of cyclosporine a and FK506 on potassium transport systems in MDCK cells. | 2001 | Exp. Nephrol. | pmid:11549851 |
| Moody BR and Sengelmann RD | Topical tacrolimus in the treatment of bovine collagen hypersensitivity. | 2001 | Dermatol Surg | pmid:11553165 |
| Dunn SE et al. | Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers. | 2001 | J. Biol. Chem. | pmid:11555650 |
| Carmody M et al. | FKBP12 associates tightly with the skeletal muscle type 1 ryanodine receptor, but not with other intracellular calcium release channels. | 2001 | FEBS Lett. | pmid:11557049 |
| Schlitt HJ et al. | Replacement of calcineurin inhibitors with mycophenolate mofetil in liver-transplant patients with renal dysfunction: a randomised controlled study. | 2001 | Lancet | pmid:11558484 |
| Stewart SF et al. | Mycophenolate mofetil monotherapy in liver transplantation. | 2001 | Lancet | pmid:11558493 |
| Choi CJ and Nghiem P | Tacrolimus ointment in the treatment of chronic cutaneous graft-vs-host disease: a case series of 18 patients. | 2001 | Arch Dermatol | pmid:11559218 |
| Cacciarelli TV et al. | Primary tacrolimus (FK506) therapy and the long-term risk of post-transplant lymphoproliferative disease in pediatric liver transplant recipients. | 2001 | Pediatr Transplant | pmid:11560756 |
| Letko E et al. | Treatment of ocular cicatricial pemphigoid with tacrolimus (FK 506). | 2001 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:11561793 |
| Laham G et al. | [Acute peripheral demyelinating polyneuropathy and acute renal failure after administration of FK506]. | 2001 | Medicina (B Aires) | pmid:11563175 |
| Briggs WA et al. | Lymphocyte suppression by glucocorticoids with cyclosporine, tacrolimus, pentoxifylline, and mycophenolic acid. | 1999 | J Clin Pharmacol | pmid:11563403 |
| Nakao A et al. | Impact of tacrolimus and bone marrow augmentation on intestinal allograft survival and intragraft cytokine expression in rats. | 2001 | J Med | pmid:11563819 |
| Sindhi R et al. | Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus. | 2001 | Transplantation | pmid:11571449 |
| Takamatsu Y et al. | Intravenous cyclosporine and tacrolimus caused anaphylaxis but oral cyclosporine capsules were tolerated in an allogeneic bone marrow transplant recipient. | 2001 | Bone Marrow Transplant. | pmid:11571519 |
| Coley KC et al. | Lack of tacrolimus-induced cardiomyopathy. | 2001 | Ann Pharmacother | pmid:11573873 |
| Gingras AC et al. | Control of translation by the target of rapamycin proteins. | 2001 | Prog. Mol. Subcell. Biol. | pmid:11575159 |
| Dumont FJ | Treatment of transplant rejection: are the traditional immunosuppressants good enough? | 2001 | Curr Opin Investig Drugs | pmid:11575705 |