tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Akinetic Mutism D000405 1 associated lipids
Albuminuria D000419 18 associated lipids
Alopecia D000505 14 associated lipids
Alopecia Areata D000506 6 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amenorrhea D000568 4 associated lipids
Amputation, Traumatic D000673 2 associated lipids
Anemia D000740 21 associated lipids
Anemia, Aplastic D000741 6 associated lipids
Anemia, Hemolytic D000743 4 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Refractory D000753 3 associated lipids
Anemia, Refractory, with Excess of Blasts D000754 2 associated lipids
Aneurysm, Dissecting D000784 2 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Wiebe C et al. Class II Eplet Mismatch Modulates Tacrolimus Trough Levels Required to Prevent Donor-Specific Antibody Development. 2017 J. Am. Soc. Nephrol. pmid:28729289
Chiramel DM et al. Topical tacrolimus causing gingival hyperplasia: A case report. 2017 Dermatol Ther pmid:27572623
Choi Y et al. A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMET Plus platform. 2017 Pharmacogenomics J. pmid:26882121
Wei L et al. Therapeutic Effects of FK506 on IgA Nephropathy Rat. 2017 Kidney Blood Press. Res. pmid:29179182
Hurtgen BJ et al. Impairment of early fracture healing by skeletal muscle trauma is restored by FK506. 2017 BMC Musculoskelet Disord pmid:28606129
Rummo OO et al. ADHERE: randomized controlled trial comparing renal function in de novo kidney transplant recipients receiving prolonged-release tacrolimus plus mycophenolate mofetil or sirolimus. 2017 Transpl. Int. pmid:27754567
Hou X et al. Overexpression of Fibulin-5 attenuates burn-induced inflammation via TRPV1/CGRP pathway. 2017 Exp. Cell Res. pmid:28602628
Tang JT et al. The pharmacokinetics and pharmacodynamics of mycophenolate mofetil in younger and elderly renal transplant recipients. 2017 Br J Clin Pharmacol pmid:27753146
Kita K and Mano Y Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition. 2017 J Pharm Biomed Anal pmid:28601765
Abongwa C et al. Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient. 2017 Pediatr Blood Cancer pmid:28598573
Wu Z et al. FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. 2017 Eur. J. Clin. Pharmacol. pmid:27747372
Weidinger S et al. A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal. 2017 Br. J. Dermatol. pmid:28868633
Sharma N et al. Myositis-associated Interstitial Lung Disease: Predictors of Failure of Conventional Treatment and Response to Tacrolimus in a US Cohort. 2017 J. Rheumatol. pmid:28864644
Shahidi M Thrombosis and von Willebrand Factor. 2017 Adv. Exp. Med. Biol. pmid:27628010
Miller AK et al. Transmission of Donor-Derived Breast Carcinoma as a Recurrent Mass in a Keratolimbal Allograft. 2017 Cornea pmid:28476053
Nakagawa K et al. Immunosuppressive treatment using tacrolimus promotes pregnancy outcome in infertile women with repeated implantation failures. 2017 Am. J. Reprod. Immunol. pmid:28466977
Eleftheriadis T et al. In human cell cultures, everolimus is inferior to tacrolimus in inhibiting cellular alloimmunity, but equally effective as regards humoral alloimmunity. 2017 Int Urol Nephrol pmid:28508247
Henderson CN et al. Continuous Abdominal Irrigation for Treatment of Tertiary Peritonitis in the Immunosuppressed Patient after Solid Organ Transplant: A Novel Approach. 2017 Am Surg pmid:28424115
Mourad G et al. Incidence of Posttransplantation Diabetes Mellitus in De Novo Kidney Transplant Recipients Receiving Prolonged-Release Tacrolimus-Based Immunosuppression With 2 Different Corticosteroid Minimization Strategies: ADVANCE, A Randomized Controlled Trial. 2017 Transplantation pmid:27547871
Jin SE et al. Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump. 2017 J Vis Exp pmid:28362410
Zhang L et al. Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance. 2017 BMC Biotechnol. pmid:28356086
Bellon H et al. The Effect of Immunosuppression on Airway Integrity. 2017 Transplantation pmid:28471870
Marini BL et al. Risk of graft-versus-host disease with rituximab-containing conditioning regimens in allogeneic hematopoietic stem cell transplant. 2017 J Oncol Pharm Pract pmid:26970572
Monaghan P et al. The antimalarial action of FK506 and rapamycin: evidence for a direct effect on FK506-binding protein PfFKBP35. 2017 Parasitology pmid:28274284
Solari S et al. Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation: a pilot study. 2017 Aliment. Pharmacol. Ther. pmid:28261844
Rodríguez-Perálvarez M et al. Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis. 2017 Cochrane Database Syst Rev pmid:28362060
Cui W et al. Therapy of tacrolimus combined with corticosteroids in idiopathic membranous nephropathy. 2017 Braz. J. Med. Biol. Res. pmid:28355356
Jackson MF et al. Osteoclast precursors do not express CD68: results from CD68 promoter-driven RANK transgenic mice. 2017 FEBS Lett. pmid:28173622
Chakfe N Commentary on "Tacrolimus Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats". 2017 Eur J Vasc Endovasc Surg pmid:28169106
Siponen M et al. Topical tacrolimus, triamcinolone acetonide, and placebo in oral lichen planus: a pilot randomized controlled trial. 2017 Oral Dis pmid:28168769
Vanhove T et al. Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. 2017 Br J Clin Pharmacol pmid:28168728
Gao L et al. Low incidence of acute graft-versus-host disease with short-term tacrolimus in haploidentical hematopoietic stem cell transplantation. 2017 Leuk. Res. pmid:28273549
Mekaj AY et al. Effects of hyaluronic acid and tacrolimus on the prevention of perineural scar formation and on nerve regeneration after sciatic nerve repair in a rabbit model. 2017 Eur J Trauma Emerg Surg pmid:27194249
Qiao M et al. The Natural Course of Atopic Dermatitis and the Association with Asthma. 2017 Inflammation pmid:28063089
Aschauer C et al. Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis. 2017 PLoS ONE pmid:28060893
Dong Y et al. Risk Factors, Clinical Features, and Treatment Outcomes of Recurrent Mooren Ulcers in China. 2017 Cornea pmid:28060068
Ianiri G et al. FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in . 2017 MBio pmid:29066552
de Oliveira JTP et al. Variability index of tacrolimus serum levels in pediatric liver transplant recipients younger than 12 years: Non-adherence or risk of non-adherence? 2017 Pediatr Transplant pmid:29034612
Kim YK et al. New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients. 2017 Drug Des Devel Ther pmid:29033547
Knops N et al. Tacrolimus dose requirements in paediatric renal allograft recipients are characterized by a biphasic course determined by age and bone maturation. 2017 Br J Clin Pharmacol pmid:27966227
Komaki Y et al. Pharmacologic therapies for severe steroid refractory hospitalized ulcerative colitis: A network meta-analysis. 2017 J. Gastroenterol. Hepatol. pmid:27957761
Dutta D et al. Recruitment of calcineurin to the TCR positively regulates T cell activation. 2017 Nat. Immunol. pmid:27941787
Triñanes J et al. Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells. 2017 Am. J. Transplant. pmid:28432716
Suzuki Y et al. Improved Open-Well Stability of Affinity Column-Mediated Immunoassay Reagent for Determining Blood Tacrolimus. 2017 Ther Drug Monit pmid:28282367
Perez LE et al. Visilizumab with tacrolimus and methotrexate for GvHD prevention after allogeneic hematopoietic cell transplantation from mismatched unrelated donors. 2017 Bone Marrow Transplant. pmid:27991896
Lee SM et al. Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28673995
Naicker D et al. Nationwide conversion to generic tacrolimus in pediatric kidney transplant recipients. 2017 Pediatr. Nephrol. pmid:28660366
Wood LA et al. New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision. 2017 J. Cell Biol. pmid:28954824
Sigurgeirsson B and Luger T A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - author response. 2017 Br. J. Dermatol. pmid:28940181
Qi H et al. Integration of parallel C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. 2017 Biotechnol. Bioeng. pmid:27869289