| MeSH term | MeSH ID | Detail |
|---|---|---|
| Scorpion Stings | D065008 | 1 associated lipids |
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Retrognathia | D063173 | 1 associated lipids |
| End Stage Liver Disease | D058625 | 1 associated lipids |
| Candidiasis, Invasive | D058365 | 2 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Thrombotic Microangiopathies | D057049 | 1 associated lipids |
| Central Serous Chorioretinopathy | D056833 | 1 associated lipids |
| Leukoencephalopathies | D056784 | 3 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
| Latent Tuberculosis | D055985 | 1 associated lipids |
| Invasive Pulmonary Aspergillosis | D055744 | 1 associated lipids |
| Keratosis, Actinic | D055623 | 3 associated lipids |
| Multiple Pulmonary Nodules | D055613 | 2 associated lipids |
| Pancreatitis, Graft | D055589 | 1 associated lipids |
| Failed Back Surgery Syndrome | D055111 | 3 associated lipids |
| Primary Graft Dysfunction | D055031 | 1 associated lipids |
| Idiopathic Interstitial Pneumonias | D054988 | 1 associated lipids |
| Dendritic Cell Sarcoma, Interdigitating | D054739 | 1 associated lipids |
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | D054198 | 10 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen CH et al. | Comparison of tuberculosis infection rates in a national database of renal transplant patients with data from a single center in Taiwan. | 2014 | Transplant. Proc. | pmid:24656019 |
| Hattori Y et al. | Influence of cytochrome P450 3A5 polymorphisms on viral infection incidence in kidney transplant patients treated with tacrolimus. | 2014 | Transplant. Proc. | pmid:24656015 |
| Cusinato DA et al. | Relationship of CYP3A5 genotype and ABCB1 diplotype to tacrolimus disposition in Brazilian kidney transplant patients. | 2014 | Br J Clin Pharmacol | pmid:24528196 |
| McCormack PL | Extended-release tacrolimus: a review of its use in de novo kidney transplantation. | 2014 | Drugs | pmid:25352392 |
| Ciancio G et al. | Randomized trial of three induction antibodies in kidney transplantation: long-term results. | 2014 | Transplantation | pmid:24477186 |
| Okada K et al. | [Single institution experience of HLA-haploidentical hematopoietic stem cell transplantation for children: current problems and perspective]. | 2014 | Rinsho Ketsueki | pmid:24492043 |
| Pedroso JA et al. | Elderly kidney transplant recipient with intermittent fever: a case report of leishmaniasis with acute kidney injury during liposomal amphotericin B therapy. | 2014 | Transplant. Proc. | pmid:25242789 |
| Torres IB et al. | The Interplay between inflammation and fibrosis in kidney transplantation. | 2014 | Biomed Res Int | pmid:24991565 |
| Wada A et al. | Ribosome display and photo-cross-linking techniques for in vitro identification of target proteins of bioactive small molecules. | 2014 | Anal. Chem. | pmid:24380432 |
| Yargui L et al. | Metabolic status of 1088 patients after renal transplantation: assessment of twelve years monitoring in Algiers Mustapha Hospital. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434409 |
| Gounden V and Soldin SJ | Tacrolimus measurement: building a better immunoassay. | 2014 | Clin. Chem. | pmid:24415738 |
| Takeuchi T et al. | Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis. | 2014 | Mod Rheumatol | pmid:24261753 |
| Czubkowski P et al. | Cardiovascular risk factors after conversion from cyclosporine to tacrolimus in children after liver transplantation. | 2014 | Ann. Transplant. | pmid:25409773 |
| Guitard J et al. | An unexpected diagnosis in a renal-transplant patient with proteinuria treated with everolimus: AL amyloidosis. | 2014 | Clin. Nephrol. | pmid:24040781 |
| Spagnoletti G et al. | Conversion from Prograf to Advagraf in stable kidney transplant recipients: better renal function after 3-year follow-up. | 2014 | Transplant. Proc. | pmid:25242756 |
| Liu FL et al. | FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines. | 2014 | J. Biosci. | pmid:24499793 |
| Favennec C et al. | Consideration of the switch from twice-daily to once-daily tacrolimus in pediatric kidney transplant in daily clinical practice: pharmacokinetic parameters, patient satisfaction and medical practices. | 2014 | Pediatr Transplant | pmid:25164065 |
| Gupta AK et al. | Efficient neutrophil extracellular trap induction requires mobilization of both intracellular and extracellular calcium pools and is modulated by cyclosporine A. | 2014 | PLoS ONE | pmid:24819773 |
| Schmid S et al. | Volatility of serum creatinine relative to tacrolimus levels predicts kidney transplant rejection. | 2014 | Ann. Transplant. | pmid:25123847 |
| Guillén-Gómez E et al. | Monocyte implication in renal allograft dysfunction. | 2014 | Clin. Exp. Immunol. | pmid:24134783 |
| Farkas K et al. | Ability of different rescue therapies to save the bowel in acute, severe, steroid-refractory ulcerative colitis. | 2014 | Expert Rev Gastroenterol Hepatol | pmid:24738535 |
| Li T et al. | Effect of FK506 nanospheres on regeneration of allogeneic nerve after transplant. | 2014 | Asian Pac J Trop Med | pmid:25066398 |
| Hamilton BK and Kalaycio M | Maximizing the benefits of mycophenolate mofetil as graft-versus-host disease prophylaxis. | 2014 | Biol. Blood Marrow Transplant. | pmid:25065905 |
| Garriga-Companys S and Labrador-Horrillo M | [Chronic spontaneous urticaria]. | 2014 | Med Clin (Barc) | pmid:24120109 |
| Kurzawski M et al. | Impact of PPARA and POR polymorphisms on tacrolimus pharmacokinetics and new-onset diabetes in kidney transplant recipients. | 2014 | Pharmacogenet. Genomics | pmid:24921414 |
| Ji SM et al. | Retrospective evaluation of the effect of mycophenolate mofetil dosage on survival of kidney grafts based on biopsy results. | 2014 | Transplant. Proc. | pmid:25498056 |
| Hosohata K et al. | Association between CYP3A5 genotypes in graft liver and increase in tacrolimus biotransformation from steroid treatment in living-donor liver transplant patients. | 2014 | Drug Metab. Pharmacokinet. | pmid:23955548 |
| Foroncewicz B et al. | Cyclosporine is superior to tacrolimus in liver transplant recipients with recurrent psoriasis. | 2014 | Ann. Transplant. | pmid:25163829 |
| Kern G et al. | Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling. | 2014 | PLoS ONE | pmid:24816588 |
| Ishikawa Y and Bächinger HP | A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis. | 2014 | J. Biol. Chem. | pmid:24821723 |
| Földes G et al. | Immunosuppressive agents modulate function, growth, and survival of cardiomyocytes and endothelial cells derived from human embryonic stem cells. | 2014 | Stem Cells Dev. | pmid:24192059 |
| Heilman RL et al. | Delayed allograft inflammation following alemtuzumab induction for kidney transplantation. | 2013 Sep-Oct | Clin Transplant | pmid:23924146 |
| Benoit S and Hamm H | Psoriasis from a prosthesis: unusual Koebner phenomenon in a girl with autoamputation of the leg. | 2013 Sep-Oct | Pediatr Dermatol | pmid:23360396 |
| Zahdi MR et al. | Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus. | 2013 Sep-Oct | An Bras Dermatol | pmid:24173187 |
| Riva N et al. | [Pharmacovigilance of calcineurin inhibitor in peidatric kidney and liver transplantation]. | 2013 Nov-Dec | Farm Hosp | pmid:24256007 |
| Brodrick B et al. | Influence of treatments on prognosis for vulvar lichen sclerosus: facts and controversies. | 2013 Nov-Dec | Clin. Dermatol. | pmid:24160287 |
| Bloom RD et al. | A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients. | 2013 Nov-Dec | Clin Transplant | pmid:24118450 |
| Labirua-Iturburu A et al. | Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease. | 2013 May-Jun | Clin. Exp. Rheumatol. | pmid:23465087 |
| Chen SY et al. | Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism--a prospective, randomized, controlled study. | 2013 May-Jun | Clin Transplant | pmid:23432535 |
| Ramirez CB et al. | Completely steroid-free immunosuppression in liver transplantation: a randomized study. | 2013 May-Jun | Clin Transplant | pmid:23621629 |
| Krishna N et al. | Tacrolimus-induced paranoid delusions and fugue-like state. | 2013 May-Jun | Gen Hosp Psychiatry | pmid:22959421 |
| He L et al. | Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids. | 2013 May-Jun | J. Nephrol. | pmid:22956434 |
| Kanzelmeyer NK et al. | Correlations with six-month protocol biopsy findings in pediatric transplant recipients on low- and regular-dose CNI regimens. | 2013 Mar-Apr | Clin Transplant | pmid:23414365 |
| Tiwari R et al. | Enhancements in healthcare information technology systems: customizing vendor-supplied clinical decision support for a high-risk patient population. | 2013 Mar-Apr | J Am Med Inform Assoc | pmid:22813760 |
| Albekairy A et al. | Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipients. | 2013 Mar-Apr | Saudi J Gastroenterol | pmid:23481136 |
| LaMattina JC et al. | Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up. | 2013 Mar-Apr | Clin Transplant | pmid:23294013 |
| Alfson ED et al. | Lysis of catatonic withdrawal by propofol in a bone-marrow transplant recipient with adenovirus limbic encephalitis. | 2013 Mar-Apr | Psychosomatics | pmid:22705183 |
| Yoshida EM et al. | Canadian national retrospective chart review comparing the long term effect of cyclosporine vs. tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. | 2013 Mar-Apr | Ann Hepatol | pmid:23396740 |
| Castillo G et al. | [Acute cellular rejection in a liver transplantation patient due to changing the brand of a generic immunosuppressant]. | 2013 Jul-Sep | Rev Gastroenterol Mex | pmid:23866966 |
| Bechstein WO et al. | A comparative, randomized trial of concentration-controlled sirolimus combined with reduced-dose tacrolimus or standard-dose tacrolimus in renal allograft recipients. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953523 |
| Zhao YJ et al. | Late, severe, noninfectious diarrhea after renal transplantation: high-risk factors, therapy, and prognosis. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953533 |
| Weiler N et al. | Tacrolimus effects and side effects after liver transplantation: is there a difference between immediate and extended release? | 2013 Jul-Aug | Transplant. Proc. | pmid:23953543 |
| Stringa P et al. | Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953566 |
| Tachibana A et al. | Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes. | 2013 Jul-Aug | Xenotransplantation | pmid:23683097 |
| Favi E et al. | Tacrolimus plus mycophenolate mofetil vs. cyclosporine plus everolimus in deceased donor kidney transplant recipients: three-yr results of a single-center prospective clinical trial. | 2013 Jul-Aug | Clin Transplant | pmid:23710603 |
| Eberlin M et al. | Increased medication compliance of liver transplant patients switched from a twice-daily to a once-daily tacrolimus-based immunosuppressive regimen. | 2013 Jul-Aug | Transplant. Proc. | pmid:23726723 |
| Satyanarayan HS et al. | Efficacy and tolerability of combined treatment with NB-UVB and topical tacrolimus versus NB-UVB alone in patients with vitiligo vulgaris: a randomized intra-individual open comparative trial. | 2013 Jul-Aug | Indian J Dermatol Venereol Leprol | pmid:23760325 |
| Babalola O and Strober BE | Treatment of atopic dermatitis in pregnancy. | 2013 Jul-Aug | Dermatol Ther | pmid:23914886 |
| Conti R et al. | Jessner-Kanof disease: two effective and sure therapeutic options. | 2013 Jul-Aug | Dermatol Ther | pmid:23914897 |
| Chakkera HA et al. | Genetic differences in Native Americans and tacrolimus dosing after kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375287 |
| Tian Ch et al. | B- and T-lymphocyte attenuator/herpes virus entry mediator as early indicators for acute rejection following kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375291 |
| Yao B et al. | The incidence of posttransplantation diabetes mellitus during follow-up in kidney transplant recipients and relationship to Fok1 vitamin D receptor polymorphism. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375298 |
| Miyazaki T et al. | Two case reports of successful withdrawal of mycofenolate mofetil after living donor lobar lung transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375323 |
| Chang HY et al. | Long-term follow-up of arrhythmia characteristics and clinical outcomes in heart transplant patients. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375324 |
| Al Nahdi N et al. | First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder. | 2013 Jan-Feb | Ann Hepatol | pmid:23293209 |
| Seco-Melantuche R et al. | [Incidence of drug-induced thrombocytopenia in hospitalized patients]. | 2013 Jan-Feb | Farm Hosp | pmid:23461497 |
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| Langone A et al. | Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) Registry. | 2013 Jan-Feb | Clin Transplant | pmid:22861144 |
| Shiba H et al. | Switching from tacrolimus to cyclosporine A to prevent primary biliary cirrhosis recurrence after living-donor liver transplantation. | 2013 Apr-Jun | Int Surg | pmid:23701152 |
| Adamu B et al. | New-onset diabetes after renal transplantation: a case series as seen in a Nigerian kidney transplant population. | 2013 Apr-Jun | Niger J Clin Pract | pmid:23563475 |
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| Becker S et al. | Evaluation of a novel commercial assay for the determination of cyclosporine A, tacrolimus, sirolimus, and everolimus by liquid chromatography-tandem mass spectrometric assay. | 2013 | Ther Drug Monit | pmid:23188181 |
| Narayanan M et al. | Outcomes in African American kidney transplant patients receiving tacrolimus and mycophenolic acid immunosuppression. | 2013 | Transplantation | pmid:23423268 |
| Levitsky J et al. | Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients. | 2013 | Hepatology | pmid:22234876 |
| White M et al. | Cardiac signaling molecules and plasma biomarkers after cardiac transplantation: impact of tacrolimus versus cyclosporine. | 2013 | J. Heart Lung Transplant. | pmid:24263023 |
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| Carmona A et al. | Distinct deleterious effects of cyclosporine and tacrolimus and combined tacrolimus-sirolimus on endothelial cells: protective effect of defibrotide. | 2013 | Biol. Blood Marrow Transplant. | pmid:23845694 |
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| Maguire O et al. | Nuclear translocation of nuclear factor of activated T cells (NFAT) as a quantitative pharmacodynamic parameter for tacrolimus. | 2013 | Cytometry A | pmid:24136923 |
| Thin LW et al. | Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era. | 2013 | Inflamm. Bowel Dis. | pmid:23615528 |
| Chapin RW et al. | Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS). | 2013 | Skeletal Radiol. | pmid:23615775 |
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| MartÃn-Cano FE et al. | mTOR pathway and Ca²⺠stores mobilization in aged smooth muscle cells. | 2013 | Aging (Albany NY) | pmid:23661091 |
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| Viana RA et al. | Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast. | 2013 | Genetics | pmid:23934882 |
| Fuchs U et al. | Clinical outcome in cardiac transplant recipients receiving tacrolimus retard. | 2013 | Transplant. Proc. | pmid:23769094 |
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| Akhi SN et al. | Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus. | 2013 | Fertil. Steril. | pmid:23218920 |
| Miyauchi T et al. | Therapeutic targeting of the axonal and microvascular change associated with repetitive mild traumatic brain injury. | 2013 | J. Neurotrauma | pmid:23796228 |
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