| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Mouth Diseases | D009059 | 5 associated lipids |
| Meningococcal Infections | D008589 | 3 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ierardi E et al. | Oral tacrolimus long-term therapy in patients with Crohn's disease and steroid resistance. | 2001 | Aliment. Pharmacol. Ther. | pmid:11207512 |
| Firpi RJ et al. | Sirolimus-induced hyperlipidaemia in liver transplant recipients is not dose-dependent. | 2004 | Aliment. Pharmacol. Ther. | pmid:15113371 |
| Herrlinger KR et al. | Infliximab as rescue medication for patients with severe ulcerative/indeterminate colitis refractory to tacrolimus. | 2010 | Aliment. Pharmacol. Ther. | pmid:20175769 |
| Solari S et al. | Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation: a pilot study. | 2017 | Aliment. Pharmacol. Ther. | pmid:28261844 |
| Hisanaga Y et al. | Implication of nitric oxide synthase activity in the genesis of water immersion stress-induced gastric lesions in rats: the protective effects of FK506. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971291 |
| Hoshino H et al. | Effects of FK506 on an experimental model of colitis in rats. | 1995 | Aliment. Pharmacol. Ther. | pmid:7544633 |
| Ortiz de Frutos FJ | [New horizons in the treatment of atopic dermatitis]. | Allergol Immunopathol (Madr) | pmid:11988144 | |
| Mori F et al. | Increase of natural killer cells in children with liver transplantation-acquired food allergy. | Allergol Immunopathol (Madr) | pmid:29456038 | |
| Regueiro-GarcÃa A et al. | Haploidentical stem cell transplantation in a boy with chronic granulomatous disease. | Allergol Immunopathol (Madr) | pmid:29373243 | |
| Inoue Y et al. | Food allergy after cord blood stem cell transplantation with tacrolimus therapy in two patients who developed veno-occlusive disease. | 2012 | Allergol Int | pmid:22722810 |
| Tsuji T et al. | Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice. | 2016 | Allergol Int | pmid:26666476 |
| Miyachi Y et al. | Suplatast/tacrolimus combination therapy for refractory facial erythema in adult patients with atopic dermatitis: a meta-analysis study. | 2007 | Allergol Int | pmid:17582208 |
| Ebihara N et al. | Blood level of tacrolimus in patients with severe allergic conjunctivitis treated by 0.1% tacrolimus ophthalmic suspension. | 2012 | Allergol Int | pmid:22361511 |
| Yamamoto M et al. | A novel atopic dermatitis model induced by topical application with dermatophagoides farinae extract in NC/Nga mice. | 2007 | Allergol Int | pmid:17460441 |
| Wollenberg A et al. | Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. | 2008 | Allergy | pmid:18445188 |
| Jensen JM et al. | Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis. | 2012 | Allergy | pmid:22142306 |
| Bieber T et al. | Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis. | 2007 | Allergy | pmid:17298428 |
| Bergstrand H and Lundquist B | Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. | 1992 | Allergy | pmid:1280915 |
| Oldhoff JM et al. | Modulation of the atopy patch test: tacrolimus 0.1% compared with triamcinolone acetonide 0.1%. | 2006 | Allergy | pmid:16629794 |
| Simon D et al. | Inflammatory cell numbers and cytokine expression in atopic dermatitis after topical pimecrolimus treatment. | 2005 | Allergy | pmid:15932386 |