First MR |
Transplantation in the nineties. |
1992 |
Transplantation |
pmid:1370734
|
Naito M et al. |
Reversal of multidrug resistance by an immunosuppressive agent FK-506. |
1992 |
Cancer Chemother. Pharmacol. |
pmid:1370765
|
Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Moutabarrik A et al. |
FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells. |
1992 |
Transpl. Int. |
pmid:14621744
|
Stangl MJ et al. |
The use of FK506 and RS61443 for reversal of small-bowel rejection. |
1992 |
Transpl. Int. |
pmid:14621800
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Matsuzaki T et al. |
Liver transplantation for diethylnitrosamine-induced hepatocellular carcinoma in rats. |
1992 |
Transplant. Proc. |
pmid:1373547
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation using the cuff technique in rats. |
1992 |
Transplant. Proc. |
pmid:1376532
|
Demetris AJ et al. |
Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression. |
1992 |
Lancet |
pmid:1376851
|
Ichihashi T et al. |
Haemolytic uraemic syndrome during FK506 therapy. |
1992 |
Lancet |
pmid:1376852
|
Bergstrand H et al. |
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1281879
|
DiLella AG et al. |
Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1281998
|
Sawada M et al. |
Down regulation of CD4 expression in cultured microglia by immunosuppressants and lipopolysaccharide. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1282000
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs receiving FK 506. |
1992 |
Transplant. Proc. |
pmid:1379754
|
Yoshimura R et al. |
A comparative study of cyclosporine vs FK 506: role of kidney microsomal cytochrome P-450. |
1992 |
Transplant. Proc. |
pmid:1379755
|
Yamada K et al. |
FK 506-induced juxtaglomerular apparatus hyperplasia and tubular damage in rat kidney--morphologic and biologic analysis. |
1992 |
Transplant. Proc. |
pmid:1379756
|
Norris AA et al. |
Protective effects of cyclophosphamide, cyclosporin A and FK506 against antigen-induced lung eosinophilia in guinea-pigs. |
1992 |
Clin. Exp. Immunol. |
pmid:1381297
|
Karpas A et al. |
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1381509
|
Yatscoff RW and Shaw LM |
Therapeutic monitoring of cyclosporine, FK-506, and rapamycin. |
1992 |
Ther Drug Monit |
pmid:1381530
|
Liu J et al. |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. |
1992 |
Int. Arch. Allergy Immunol. |
pmid:1384862
|
Mochizuki M et al. |
Preclinical and clinical study of FK506 in uveitis. |
1992 |
Curr. Eye Res. |
pmid:1385045
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
Jusko WJ and D'Ambrosio R |
Monitoring FK 506 concentrations in plasma and whole blood. |
1991 |
Transplant. Proc. |
pmid:1721260
|
Venkataramanan R et al. |
Pharmacokinetics of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721261
|
Christians U et al. |
High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721262
|
Beysens AJ et al. |
FK 506: monitoring in plasma or in whole blood? |
1991 |
Transplant. Proc. |
pmid:1721263
|
Grenier FC et al. |
A whole blood FK 506 assay for the IMx analyzer. |
1991 |
Transplant. Proc. |
pmid:1721264
|
Friob MC et al. |
A combined HPLC-ELISA evaluation of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721265
|
Machida M et al. |
Effect of temperature and hematocrit on plasma concentration of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721266
|
Akselband Y et al. |
Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts. |
1991 |
Transplant. Proc. |
pmid:1721292
|
Schreiber SL et al. |
Immunophilin-ligand complexes as probes of intracellular signaling pathways. |
1991 |
Transplant. Proc. |
pmid:1721293
|
Ullman KS et al. |
Site of action of cyclosporine and FK 506 in the pathways of communication between the T-lymphocyte antigen receptor and the early activation genes. |
1991 |
Transplant. Proc. |
pmid:1721294
|
Sigal NH et al. |
Is FKBP involved in the immunosuppressive and/or toxic mechanism of action of FK 506? |
1991 |
Transplant. Proc. |
pmid:1721295
|
Bierer BE et al. |
FK 506 and rapamycin: molecular probes of T-lymphocyte activation. |
1991 |
Transplant. Proc. |
pmid:1721296
|
Tanida I et al. |
Yeast cyclophilin-related gene encodes a nonessential second peptidyl-prolyl cis-trans isomerase associated with the secretory pathway. |
1991 |
Transplant. Proc. |
pmid:1721297
|
O'Neill EA et al. |
The FK 506-sensitive nature of the interleukin-2 promoter is derived from a specific array of multiple regulatory elements. |
1991 |
Transplant. Proc. |
pmid:1721298
|
Motta I et al. |
FK 506 favors the generation of memory T cells in vitro. |
1991 |
Transplant. Proc. |
pmid:1721324
|
Nakata S et al. |
Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats. |
1991 |
Transplant. Proc. |
pmid:1721325
|
Cooper MH et al. |
Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect. |
1991 |
Transplant. Proc. |
pmid:1721326
|
Didlake R and Grogan J |
Effect of FK 506 on rat leukocyte chemotaxis. |
1991 |
Transplant. Proc. |
pmid:1721327
|
Hultsch T and Hohman RJ |
Categorizing receptor-signaling pathways with FK 506 and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721328
|
Takai K et al. |
Immunosuppressive effects of FK 506 on rat lymphoid organs. |
1991 |
Transplant. Proc. |
pmid:1721329
|
Whiteside TL et al. |
Serial monitoring of immunologic function and phenotype of lymphocytes in the blood of transplanted patients randomized to cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721356
|
de Paulis A et al. |
Characterization of the anti-inflammatory effect of FK-506 on human mast cells. |
1991 |
J. Immunol. |
pmid:1721644
|
Frayha HH et al. |
Lymphoproliferative disorder in a liver transplant patient on FK 506. |
1991 |
Lancet |
pmid:1703258
|
Van Thiel DH et al. |
Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721357
|
Burman K and Crawford DH |
Effect of FK 506 on Epstein-Barr virus specific cytotoxic T cells. |
1991 |
Lancet |
pmid:1703259
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in adult cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721358
|
Nalesnik MA et al. |
Lymphoproliferative disorders arising under immunosuppression with FK 506: initial observations in a large transplant population. |
1991 |
Transplant. Proc. |
pmid:1703335
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721359
|
Armitage JM et al. |
A clinical trial of FK 506 as primary and rescue immunosuppression in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1703336
|
Dew MA et al. |
Quality-of-life advantages of FK 506 vs conventional immunosuppressive drug therapy in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721360
|
Gordon RD et al. |
Liver transplantation under cyclosporine: a decade of experience. |
1991 |
Transplant. Proc. |
pmid:1703339
|
Shapiro R et al. |
FK 506 in clinical kidney transplantation. |
1991 |
Transplant. Proc. |
pmid:1721361
|
Todo S et al. |
One hundred ten consecutive primary orthotopic liver transplants under FK 506 in adults. |
1991 |
Transplant. Proc. |
pmid:1703340
|
McCauley J et al. |
Renal transplantation under FK 506 in patients with previous loss of renal function due to hemolytic uremic syndrome. |
1991 |
Transplant. Proc. |
pmid:1721362
|
Zeevi A et al. |
Correlation between bioassayed plasma levels of FK 506 and lymphocyte growth from liver transplant biopsies with histological evidence of rejection. |
1991 |
Transplant. Proc. |
pmid:1703341
|
Winkler M et al. |
Association of elevated FK 506 plasma levels with nephrotoxicity in liver-grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721389
|
Schmidt RJ et al. |
Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721390
|
Tze WJ et al. |
Effect of FK 506 on glucose metabolism and insulin secretion in normal rats. |
1991 |
Transplant. Proc. |
pmid:1721391
|
Doi R et al. |
Mechanisms by which FK 506 affects exocrine pancreas in rats. |
1991 |
Transplant. Proc. |
pmid:1721392
|
Rilo HL et al. |
Effect of FK 506 on function of human islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1721393
|
Carroll PB et al. |
Synexin: a target protein for toxic effects of cyclosporine and FK 506 in endocrine cells. |
1991 |
Transplant. Proc. |
pmid:1721394
|
Cooper MH et al. |
The induction of pseudo-graft-versus-host disease following syngeneic bone marrow transplantation using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721419
|
Boggs S et al. |
FK 506 has no short-term effects on endogenous or exogenous myeloid reconstitution in irradiated mice. |
1991 |
Transplant. Proc. |
pmid:1721420
|
Cooper MH et al. |
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721421
|
Yoshimi F et al. |
Canine total orthotopic small bowel transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721422
|
Santiago SF et al. |
Effect of donor pretreatment with FK 506 upon small intestine allotransplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721423
|
Murase N et al. |
Lymphocyte traffic and graft-versus-host disease after fully allogeneic small bowel transplantation. |
1991 |
Transplant. Proc. |
pmid:1721424
|
Hohlfeld R |
[Current therapy of multiple sclerosis: value of cyclosporin A and FK 506]. |
1991 |
Nervenarzt |
pmid:1709725
|
Kay JE et al. |
Inhibition of T and B lymphocyte proliferation by rapamycin. |
1991 |
Immunology |
pmid:1709916
|
Ringe D |
Immunosuppression. Binding by design. |
1991 |
Nature |
pmid:1710317
|
Tropschug M and Hofmann R |
FK506 and protein kinase C. |
1991 |
Nature |
pmid:1710319
|
Albers MW et al. |
Relationship of FKBP to PKCI-2. |
1991 |
Nature |
pmid:1710782
|
Stevens C et al. |
The effects of immunosuppressive agents on in vitro production of human immunoglobulins. |
1991 |
Transplantation |
pmid:1710843
|
Metcalfe S and Milner J |
Evidence that FK506 and rapamycin block T cell activation at different sites relative to early reversible phosphorylation involving the protein phosphatases PP1 and PP2A. |
1991 |
Transplantation |
pmid:1710844
|
Abu-Elmagd K et al. |
Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. |
1991 |
Transplant. Proc. |
pmid:1721451
|
Thomson AW et al. |
Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study. |
1991 |
Transplant. Proc. |
pmid:1721452
|
Sainsbury TS et al. |
Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata. |
1991 |
Transplant. Proc. |
pmid:1721453
|
Fujino Y et al. |
FK 506 treatment of experimental autoimmune uveoretinitis in primates. |
1991 |
Transplant. Proc. |
pmid:1721454
|
Liversidge J et al. |
FK 506 modulates accessory cell adhesion molecule expression and inhibits CD4 lymphocyte adhesion to retinal pigment epithelial cells in vitro: implications for therapy of uveoretinitis. |
1991 |
Transplant. Proc. |
pmid:1721455
|
Mochizuki M et al. |
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behçet's disease. Japanese FK 506 Study Group on Refractory Uveitis. |
1991 |
Transplant. Proc. |
pmid:1721456
|
Roat MI et al. |
Treatment of Cogan's syndrome with FK 506: a case report. |
1991 |
Transplant. Proc. |
pmid:1721457
|
Simmons RL and Wang SC |
New horizons in immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1714645
|
Calne RY |
Immunosuppression for organ grafting. |
1991 |
Transplant. Proc. |
pmid:1714646
|
Starzl TE et al. |
Notes on FK 506. |
1991 |
Transplant. Proc. |
pmid:1714647
|
Haba T et al. |
Pathological and immunohistochemical examination in the rat treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1714649
|
Lautenschlager I et al. |
Efficiency of FK 506 and CyA to prevent acute cellular rejection of pig liver allografts. |
1991 |
Transplant. Proc. |
pmid:1714650
|
Epand RF and Epand RM |
The new potent immunosuppressant FK-506 reverses multidrug resistance in Chinese hamster ovary cells. |
1991 |
Anticancer Drug Des. |
pmid:1714737
|
Christians U et al. |
Isolation of an immunosuppressive metabolite of FK506 generated by human microsome preparations. |
1991 |
Clin. Biochem. |
pmid:1714802
|
Wu J et al. |
Comparative immunoregulatory effects of rapamycin, FK 506 and cyclosporine on mitogen-induced cytokine production and lymphoproliferation. |
1991 |
Transplant. Proc. |
pmid:1703683
|
Sakai K et al. |
[The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents--comparison with cyclosporin A]. |
1991 |
No To Shinkei |
pmid:1716937
|
Yoshimura R et al. |
A comparative study between cyclosporine and FK 506 effects on renal microsomal P-450. |
1991 |
Transplant. Proc. |
pmid:1703686
|
Miyagawa S et al. |
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA. |
1991 |
Transplant. Proc. |
pmid:1703687
|
Carroll PB et al. |
Effect of the immunosuppressant FK 506 on insulin release from adult rat islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1703688
|
Fujino Y et al. |
FK506 treatment of S-antigen induced uveitis in primates. |
1991 |
Curr. Eye Res. |
pmid:1717199
|
Sakr MF et al. |
Protective effect of FK 506 against hepatic ischemia in rats. |
1991 |
Transplant. Proc. |
pmid:1703689
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1703690
|