tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Mouth Diseases D009059 5 associated lipids
Meningococcal Infections D008589 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
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Siniscalchi A et al. Opioid-induced hyperalgesia and rapid opioid detoxification after tacrolimus administration. 2008 Anesth. Analg. pmid:18227327
Brooksbank RL et al. Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture. 1998 Anesthesiology pmid:9743407
Chini EN and Walker H FK506 (tacrolimus) increases halothane-induced Ca2+ release from skeletal muscle sarcoplasmic reticulum. 2000 Anesthesiology pmid:10781282
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Parodi A et al. [Treatment of rosacea]. 2011 Ann Dermatol Venereol pmid:21907876
Mahé E et al. [Plane warts in areas of atopic dermatitis treated with tacrolimus ointment]. 2006 Aug-Sep Ann Dermatol Venereol pmid:17053745
Girault PY et al. [Topical tacrolimus in chronic actinic dermatitis]. 2008 Ann Dermatol Venereol pmid:18929923
Rouxel AM et al. [Tacrolimus mouthwash as second-line treatment for erosive oral lichen planus]. 2010 Ann Dermatol Venereol pmid:20932447
Skowron F et al. [Important systemic absorption of topical tacrolimus during treatment of severe pemphigus vulgaris]. 2005 Ann Dermatol Venereol pmid:15924053
Nouchi A et al. [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. 2015 Ann Dermatol Venereol pmid:25778634
Reynaert G et al. [Streptococcal impetigo at topical tacrolimus application sites in a woman with atopic dermatitis]. 2007 Ann Dermatol Venereol pmid:17389853
Paul C [Science, marketing and pharmacovigilance: the example of topical calcineurin inhibitors]. 2007 Ann Dermatol Venereol pmid:18033059
Al Gain M et al. [Sirolimus-induced lymphedema in a kidney-transplant recipient: Partial recovery after changeover to tacrolimus]. 2015 Ann Dermatol Venereol pmid:25683011
Chiheb S et al. [Behçet's disease]. 2003 Jun-Jul Ann Dermatol Venereol pmid:13679709
Baubion E et al. [Oral lichen planus and treatment with topical tacrolimus rinse]. 2009 Ann Dermatol Venereol pmid:19328313
Schmutz JL et al. [Kaposi's sarcoma in an AIDS patient after application of tacrolimus (Protopic)]. 2006 Ann Dermatol Venereol pmid:16800194
Henno A et al. [Improvement of Netherton syndrome associated erythroderma in two adult sisters through use of topical pimecrolimus]. 2006 Ann Dermatol Venereol pmid:16495860
Michel JL and Gain P [Topical tacrolimus treatment for ocular cicatricial pemphigoid]. 2006 Ann Dermatol Venereol pmid:16508602
Lacour JP [Topical tacrolimus in dermatology: what can one expect?]. 2001 Ann Dermatol Venereol pmid:11908129
Macario-Barrel A et al. [Mouth ulcers in patients receiving tacrolimus]. 2001 Ann Dermatol Venereol pmid:11908135
Firmin D et al. [Tacrolimus ointment in the treatment of chronic cutaneous graft-versus-host disease]. 2008 Ann Dermatol Venereol pmid:18374862
Ferraro V et al. [Efficacy of topical tacrolimus in Hailey-Hailey disease]. 2006 Ann Dermatol Venereol pmid:16760841
Fery-Blanco C et al. [Disseminated molluscum contagiosum during topical treatment of atopic dermatitis with tacrolimus: efficacy of cidofovir]. 2007 Ann Dermatol Venereol pmid:17507844
Schmutz J et al. [Gingival hypertrophy and tacrolimus]. 2000 Jun-Jul Ann Dermatol Venereol pmid:10930868
Lübbe J and Saurat JH [A monograph on topical tacrolimus (Protopic]. 2003 Ann Dermatol Venereol pmid:12700537
de Prost Y [The value of topical immunosuppressors in the treatment of atopic dermatitis in children]. 2005 Ann Dermatol Venereol pmid:15984296
de Prost Y [Can the precautionary principle obstruct therapeutic progress?]. 2005 Aug-Sep Ann Dermatol Venereol pmid:16230911