tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Mouth Diseases D009059 5 associated lipids
Meningococcal Infections D008589 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Schmutz JL et al. [Contact allergy with tacrolimus then pimecrolimus]. 2008 Ann Dermatol Venereol pmid:18342086
de Prost Y [The value of topical immunosuppressors in the treatment of atopic dermatitis in children]. 2005 Ann Dermatol Venereol pmid:15984296
Nicolie B [What is the treatment for atopic dermatitis flares in children?]. 2005 Ann Dermatol Venereol pmid:15984308
Abbott KC et al. Differing manifestations of hepatitis C and tacrolimus on hospitalized diabetes mellitus occurring after kidney transplantation. 2005 Ann Epidemiol pmid:16118000
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Al Nahdi N et al. First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder. 2013 Jan-Feb Ann Hepatol pmid:23293209
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Yoshida EM et al. Canadian national retrospective chart review comparing the long term effect of cyclosporine vs. tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. 2013 Mar-Apr Ann Hepatol pmid:23396740
Qin X et al. Multi-center Performance Evaluations of Tacrolimus and Cyclosporine Electrochemiluminescence Immunoassays in the Asia-Pacific Region. 2018 Ann Lab Med pmid:29214751
Ikitimur B et al. Long-Term Impact of Different Immunosuppressive Drugs on QT and PR Intervals in Renal Transplant Patients. 2015 Ann Noninvasive Electrocardiol pmid:25367596
Yalçindag FN et al. Effectiveness of tacrolimus in high-risk limbal allo-graft transplantation. 2008 Fall-Winter Ann Ophthalmol (Skokie) pmid:19230352
Yalçindağ FN et al. Penetration of topically applied tacrolimus into the aqueous humor in Behçet's disease. 2007 Ann Ophthalmol (Skokie) pmid:17914200
Goldust M et al. Treatment of seborrheic dermatitis: the efficiency of sertaconazole 2% cream vs. tacrolimus 0.03% cream. 2013 Ann Parasitol pmid:24171300
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Hanf W et al. [An unusual native kidney neoplasm presenting in a kidney graft recipient]. 2012 Ann Pathol pmid:23010406
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Copacia JA et al. 70% Ethanol for Decontamination of Central Venous Lines Exposed to Calcineurin Inhibitors. 2018 Ann Pharmacother pmid:28838253
Hui RL et al. Association between exposure to topical tacrolimus or pimecrolimus and cancers. 2009 Ann Pharmacother pmid:19903860
Mathis AS Comment: delayed wound healing with sirolimus after liver transplant. 2003 Ann Pharmacother pmid:12639183
Shaeffer MS et al. Interaction between FK506 and erythromycin. 1994 Ann Pharmacother pmid:7513563
Su VCh et al. Impact of Mycophenolate Mofetil Dose Reduction on Allograft Outcomes in Kidney Transplant Recipients on Tacrolimus-Based Regimens: A Systematic Review. 2011 Ann Pharmacother pmid:21304036
Chenhsu RY et al. Renal allograft dysfunction associated with rifampin-tacrolimus interaction. 2000 Ann Pharmacother pmid:10669182
Coley KC et al. Lack of tacrolimus-induced cardiomyopathy. 2001 Ann Pharmacother pmid:11573873
Takahashi K et al. Lansoprazole-tacrolimus interaction in Japanese transplant recipient with CYP2C19 polymorphism. 2004 Ann Pharmacother pmid:15010519
Guerra AA et al. Cyclosporine versus tacrolimus in immunosuppressive maintenance regimens in renal transplants in Brazil: survival analysis from 2000 to 2004. 2010 Ann Pharmacother pmid:20009005
Murray M et al. Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. 1998 Ann Pharmacother pmid:9640479
Hebert MF and Lam AY Diltiazem increases tacrolimus concentrations. 1999 Ann Pharmacother pmid:10410178
Pierce DA and Reeves-Daniel AM Ranolazine-tacrolimus interaction. 2010 Ann Pharmacother pmid:20876828
Lam S et al. Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction? 2008 Ann Pharmacother pmid:18594053
Hooks MA Tacrolimus, a new immunosuppressant--a review of the literature. 1994 Ann Pharmacother pmid:7518710
Morris RG Immunosuppressant drug monitoring: is the laboratory meeting clinical expectations? 2005 Ann Pharmacother pmid:15590877
Skaehill PA Tacrolimus in dermatologic disorders. 2001 Ann Pharmacother pmid:11346066
Gianni LM and Sulli MM Topical tacrolimus in the treatment of atopic dermatitis. 2001 Jul-Aug Ann Pharmacother pmid:11485148
Seifeldin RA et al. Nifedipine interaction with tacrolimus in liver transplant recipients. 1997 Ann Pharmacother pmid:9161650
Kaushik P et al. Miller fisher variant of guillain-barre syndrome requiring a cardiac pacemaker in a patient on tacrolimus after liver transplantation. 2005 Ann Pharmacother pmid:15855240
Page RL et al. Potential elevation of tacrolimus trough concentrations with concomitant metronidazole therapy. 2005 Ann Pharmacother pmid:15855244
Bax K et al. Rapid resolution of tacrolimus intoxication-induced AKI with a corticosteroid and phenytoin. 2014 Ann Pharmacother pmid:25104567
Ibrahim RB et al. Tacrolimus-clarithromycin interaction in a patient receiving bone marrow transplantation. 2002 Ann Pharmacother pmid:12452763
Schonder KS et al. Tacrolimus and lopinavir/ritonavir interaction in liver transplantation. 2003 Ann Pharmacother pmid:14632538
Outeda Macías M et al. Tacrolimus-itraconazole interaction in a kidney transplant patient. 2000 Ann Pharmacother pmid:10772445
Chisholm MA and Middleton MD Modified-release tacrolimus. 2006 Ann Pharmacother pmid:16449540
Hiraoka S et al. Readministration of calcineurin inhibitors for ulcerative colitis. 2012 Ann Pharmacother pmid:23032660
Ibrahim RB et al. Tacrolimus disposition in the ascitic fluid of a bone marrow transplant patient. 2010 Ann Pharmacother pmid:20371750
Thompson PA and Mosley CA Tacrolimus-phenytoin interaction. 1996 Ann Pharmacother pmid:8740340
Guilbeau JM Delayed wound healing with sirolimus after liver transplant. 2002 Ann Pharmacother pmid:12196058
Capone D et al. Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient. 1999 Ann Pharmacother pmid:10534229
Lee TJ and Kennedy LA Tacrolimus: an alternative for graft-versus-host disease prevention. 2000 Ann Pharmacother pmid:10917386