| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Mouth Diseases | D009059 | 5 associated lipids |
| Meningococcal Infections | D008589 | 3 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tang S and Lai KN | Quiz page. Posttransplantation lymphoproliferative disorder (PTLD) involving the brain and the allograft. | 2005 | Am. J. Kidney Dis. | pmid:15806458 |
| Rao PS | Nephrotic syndrome in patients with peripheral blood stem cell transplant. | 2005 | Am. J. Kidney Dis. | pmid:15806483 |
| de Mattos AM et al. | Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. | 2000 | Am. J. Kidney Dis. | pmid:10676738 |
| Kooman JP et al. | A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy. | 2001 | Am. J. Kidney Dis. | pmid:11382685 |
| Choudhry S et al. | Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. | 2009 | Am. J. Kidney Dis. | pmid:19268410 |
| Birdwell KA et al. | Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study. | 2009 | Am. J. Kidney Dis. | pmid:19185404 |
| Haas M et al. | Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicity. | 1999 | Am. J. Kidney Dis. | pmid:10401019 |
| Wong TY et al. | Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus. | 1999 | Am. J. Kidney Dis. | pmid:10585325 |
| Rostaing L et al. | Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial. | 2016 | Am. J. Kidney Dis. | pmid:26717860 |
| Hricik DE | Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583939 |
| Pescovitz MD and Govani M | Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583940 |
| Tang S et al. | Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. | 2003 | Am. J. Kidney Dis. | pmid:14582073 |
| Pham PT et al. | Cyclosporine and tacrolimus-associated thrombotic microangiopathy. | 2000 | Am. J. Kidney Dis. | pmid:11007689 |
| Revelo MP et al. | A 14-year-old boy with kidney allograft failure in the first month after transplantation. | 2000 | Am. J. Kidney Dis. | pmid:11007695 |
| Vischini G et al. | Increased plasma levels of tacrolimus after ingestion of green tea. | 2011 | Am. J. Kidney Dis. | pmid:21787983 |
| van Duijnhoven EM et al. | A late episode of post-transplant diabetes mellitus during active hepatitis C infection in a renal allograft recipient using tacrolimus. | 2002 | Am. J. Kidney Dis. | pmid:12087579 |
| Moes AD et al. | Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial. | 2017 | Am. J. Kidney Dis. | pmid:28259499 |
| Wong KM et al. | Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. | 2000 | Am. J. Kidney Dis. | pmid:10739787 |
| Böhmig GA et al. | Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft. | 2000 | Am. J. Kidney Dis. | pmid:10739788 |
| Starzl TE et al. | Tacrolimus (FK506) and the pharmaceutical/academic/regulatory gauntlet. | 1998 | Am. J. Kidney Dis. | pmid:9631858 |
| Lum EL et al. | Acute Kidney Allograft Rejection Precipitated by Lenalidomide Treatment for Multiple Myeloma. | 2017 | Am. J. Kidney Dis. | pmid:28189378 |
| Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
| Chen W et al. | Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: A multicenter randomized clinical trial. | 2011 | Am. J. Kidney Dis. | pmid:21177013 |
| First MR | Renal transplantation for the nephrologist: new immunosuppressive drugs. | 1992 | Am. J. Kidney Dis. | pmid:1371201 |
| Paoletti E et al. | ACE inhibitors and persistent left ventricular hypertrophy after renal transplantation: a randomized clinical trial. | 2007 | Am. J. Kidney Dis. | pmid:17591533 |
| Mertz D et al. | Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus. | 2009 | Am. J. Kidney Dis. | pmid:19346040 |
| Israni A et al. | Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. | 2002 | Am. J. Kidney Dis. | pmid:11877596 |
| Soi V et al. | Altered mental status in a kidney transplant recipient receiving tacrolimus. | 2008 | Am. J. Kidney Dis. | pmid:18155524 |
| Reese PP et al. | Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial. | 2017 | Am. J. Kidney Dis. | pmid:27940063 |
| Tsinalis D et al. | Acute renal failure in a renal allograft recipient treated with intravenous immunoglobulin. | 2002 | Am. J. Kidney Dis. | pmid:12200824 |
| Asif A et al. | Peritoneoscopic placement of peritoneal dialysis catheter and bowel perforation: experience of an interventional nephrology program. | 2003 | Am. J. Kidney Dis. | pmid:14655200 |
| Grinyó JM et al. | Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial. | 2017 | Am. J. Kidney Dis. | pmid:27889299 |
| Lien YH | Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. | 2016 | Am. J. Med. | pmid:26714210 |
| Bar J et al. | Is immunosuppression therapy in renal allograft recipients teratogenic? A single-center experience. | 2003 | Am. J. Med. Genet. A | pmid:12476448 |
| Perez-Aytes A et al. | In utero exposure to mycophenolate mofetil: a characteristic phenotype? | 2008 | Am. J. Med. Genet. A | pmid:18074358 |
| Chen W et al. | Outcomes of tacrolimus therapy in adults with refractory membranous nephrotic syndrome: a prospective, multicenter clinical trial. | 2013 | Am. J. Med. Sci. | pmid:22627258 |
| Hsu MS et al. | Clinical features and outcome of tuberculosis in solid organ transplant recipients. | 2007 | Am. J. Med. Sci. | pmid:17700199 |
| Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
| Chen M et al. | Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. | 2010 | Am. J. Med. Sci. | pmid:20220333 |
| Araujo LP et al. | Interaction of the anti-inflammatory annexin A1 protein and tacrolimus immunosuppressant in the renal function of rats. | 2010 | Am. J. Nephrol. | pmid:20484890 |
| Ferreira A et al. | Donor-Specific Anti-Human Leukocyte Antigens Antibodies, Acute Rejection, Renal Function, and Histology in Kidney Transplant Recipients Receiving Tacrolimus and Everolimus. | 2017 | Am. J. Nephrol. | pmid:28511172 |
| Issa N et al. | Calcineurin inhibitor nephrotoxicity: a review and perspective of the evidence. | 2013 | Am. J. Nephrol. | pmid:23796509 |
| Vural A et al. | Assessment of oxidative stress in the early posttransplant period: comparison of cyclosporine A and tacrolimus-based regimens. | 2005 May-Jun | Am. J. Nephrol. | pmid:15925859 |
| Li J et al. | Evaluation of mycophenolic acid exposure using a limited sampling strategy in renal transplant recipients. | 2013 | Am. J. Nephrol. | pmid:23689735 |
| Lee CT et al. | Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism. | 2011 | Am. J. Nephrol. | pmid:21691056 |
| Soubhia RM et al. | Tacrolimus and nonsteroidal anti-inflammatory drugs: an association to be avoided. | 2005 Jul-Aug | Am. J. Nephrol. | pmid:15976495 |
| Dai DS et al. | Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. | 2015 | Am. J. Nephrol. | pmid:26439819 |
| El-Dahshan KF et al. | Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study. | 2006 | Am. J. Nephrol. | pmid:16804292 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Weir MR et al. | Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. | 2004 Jul-Aug | Am. J. Nephrol. | pmid:15237243 |