Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gerber DA et al. | Immunosuppressive agents: recent developments in molecular action and clinical application. | 1998 | Transplant. Proc. | pmid:9636637 |
Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |
Resch K and Szamel M | Molecular mechanisms of the immunosuppressive action of cyclosporin A. | 1997 Sep-Oct | Int. J. Immunopharmacol. | pmid:9637358 |
Baldari CT et al. | NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. | 1998 | Biologicals | pmid:9637743 |
Abraham RT | Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. | 1998 | Curr. Opin. Immunol. | pmid:9638370 |
Takahara S et al. | A comparative study of FK506 granules and capsules in renal transplant recipients. | 1998 | Transpl. Int. | pmid:9638846 |
Morris-Stiff G and Jurewicz WA | Single centre experience with mycophenolate mofetil for refractory rejection in cadaveric renal transplantation. | 1998 | Transpl. Int. | pmid:9638849 |
Murray M et al. | Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. | 1998 | Ann Pharmacother | pmid:9640479 |
Kuwata T et al. | A role of calcineurin in coreceptor regulation during differentiation of Cd4+Cd8+ T cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9642110 |
Gruessner RW et al. | Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. | 1998 | Clin Transplant | pmid:9642520 |
Gabe SM et al. | The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. | 1998 | Gastroenterology | pmid:9649460 |
Canzanello VJ et al. | Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506). | 1998 | Liver Transpl Surg | pmid:9649648 |
Friberg H et al. | Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. | 1998 | J. Neurosci. | pmid:9651198 |
Tarumi K et al. | The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. | 1998 | Immunopharmacol Immunotoxicol | pmid:9653668 |
Kommers T et al. | Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. | 1998 | Neurosci. Lett. | pmid:9654363 |
Cetinkale O et al. | Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. | 1998 | Plast. Reconstr. Surg. | pmid:9655420 |
Matsui H et al. | [Physiological role of calcineurin in central nervous system]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655961 |
Tamura K | [Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655970 |
Morozumi K et al. | [Current topics of the rejection pathology in human renal allografts]. | 1998 | Hinyokika Kiyo | pmid:9656109 |
Nishioka T et al. | [Is tacrolimus effective for ongoing renal allograft rejection?]. | 1998 | Hinyokika Kiyo | pmid:9656112 |