tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Alzheimer Disease D000544 76 associated lipids
Stomach Ulcer D013276 75 associated lipids
Leukemia D007938 74 associated lipids
Hyperlipidemias D006949 73 associated lipids
Melanoma D008545 69 associated lipids
Colitis D003092 69 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Osteosarcoma D012516 50 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Precancerous Conditions D011230 48 associated lipids
Psoriasis D011565 47 associated lipids
Leukemia P388 D007941 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hyperalgesia D006930 42 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Kim SK et al. Inflammatory mimetic microfluidic chip by immobilization of cell adhesion molecules for T cell adhesion. 2012 Analyst pmid:22822477
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Lang-Lazdunski L et al. The effects of FK506 on neurologic and histopathologic outcome after transient spinal cord ischemia induced by aortic cross-clamping in rats. 2001 Anesth. Analg. pmid:11323353
Siniscalchi A et al. Opioid-induced hyperalgesia and rapid opioid detoxification after tacrolimus administration. 2008 Anesth. Analg. pmid:18227327
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Moncourier M et al. [Granulomatous periocular eruption]. Ann Dermatol Venereol pmid:28410769
Elloudi S et al. [Frontal fibrosing alopecia: A prospective study of 20 cases]. Ann Dermatol Venereol pmid:28258757
Mirkamali A et al. [Ulcerated necrobiosis lipoidica: successful treatment with topical tacrolimus and hydroxychloroquine]. 2010 Aug-Sep Ann Dermatol Venereol pmid:20804904
Parodi A et al. Treatment of rosacea. 2011 Ann Dermatol Venereol pmid:22183101
Schmutz JL et al. [Pimecrolimus and vaccinations]. 2007 Jun-Jul Ann Dermatol Venereol pmid:17702119
Alquier-Bouffard A et al. [Chronic actinic dermatitis: treatment with topical tacrolimus (two cases)]. 2007 Jun-Jul Ann Dermatol Venereol pmid:17657183
Schmutz JL [No increased risk of cancer under pimecrolimus]. 2016 Ann Dermatol Venereol pmid:26708204
Parodi A et al. [Treatment of rosacea]. 2011 Ann Dermatol Venereol pmid:21907876
Mahé E et al. [Plane warts in areas of atopic dermatitis treated with tacrolimus ointment]. 2006 Aug-Sep Ann Dermatol Venereol pmid:17053745
Girault PY et al. [Topical tacrolimus in chronic actinic dermatitis]. 2008 Ann Dermatol Venereol pmid:18929923
Rouxel AM et al. [Tacrolimus mouthwash as second-line treatment for erosive oral lichen planus]. 2010 Ann Dermatol Venereol pmid:20932447
Schmutz JL et al. [Contact allergy with tacrolimus then pimecrolimus]. 2008 Ann Dermatol Venereol pmid:18342086
Skowron F et al. [Important systemic absorption of topical tacrolimus during treatment of severe pemphigus vulgaris]. 2005 Ann Dermatol Venereol pmid:15924053
Martel J et al. [Subcutaneous mycosis due to Scopulariopsis brevicaulis in an immunocompromised patient]. 2001 Ann Dermatol Venereol pmid:11275588
Nouchi A et al. [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. 2015 Ann Dermatol Venereol pmid:25778634
Reynaert G et al. [Streptococcal impetigo at topical tacrolimus application sites in a woman with atopic dermatitis]. 2007 Ann Dermatol Venereol pmid:17389853
Paul C [Science, marketing and pharmacovigilance: the example of topical calcineurin inhibitors]. 2007 Ann Dermatol Venereol pmid:18033059
Chiheb S et al. [Behçet's disease]. 2003 Jun-Jul Ann Dermatol Venereol pmid:13679709
Baubion E et al. [Oral lichen planus and treatment with topical tacrolimus rinse]. 2009 Ann Dermatol Venereol pmid:19328313
Schmutz JL et al. [Kaposi's sarcoma in an AIDS patient after application of tacrolimus (Protopic)]. 2006 Ann Dermatol Venereol pmid:16800194
Henno A et al. [Improvement of Netherton syndrome associated erythroderma in two adult sisters through use of topical pimecrolimus]. 2006 Ann Dermatol Venereol pmid:16495860
Michel JL and Gain P [Topical tacrolimus treatment for ocular cicatricial pemphigoid]. 2006 Ann Dermatol Venereol pmid:16508602
Lacour JP [Topical tacrolimus in dermatology: what can one expect?]. 2001 Ann Dermatol Venereol pmid:11908129
Macario-Barrel A et al. [Mouth ulcers in patients receiving tacrolimus]. 2001 Ann Dermatol Venereol pmid:11908135
Firmin D et al. [Tacrolimus ointment in the treatment of chronic cutaneous graft-versus-host disease]. 2008 Ann Dermatol Venereol pmid:18374862
Ferraro V et al. [Efficacy of topical tacrolimus in Hailey-Hailey disease]. 2006 Ann Dermatol Venereol pmid:16760841
Lübbe J and Saurat JH [A monograph on topical tacrolimus (Protopic]. 2003 Ann Dermatol Venereol pmid:12700537
de Prost Y [The value of topical immunosuppressors in the treatment of atopic dermatitis in children]. 2005 Ann Dermatol Venereol pmid:15984296
Nicolie B [What is the treatment for atopic dermatitis flares in children?]. 2005 Ann Dermatol Venereol pmid:15984308
de Prost Y [Can the precautionary principle obstruct therapeutic progress?]. 2005 Aug-Sep Ann Dermatol Venereol pmid:16230911