Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Moon BJ et al. | Effect of chronic rhinosinusitis on liver transplant patients. | 2009 Sep-Oct | Am J Rhinol Allergy | pmid:19807981 |
Reams BD and Palmer SM | Sublingual tacrolimus for immunosuppression in lung transplantation: a potentially important therapeutic option in cystic fibrosis. | 2002 | Am J Respir Med | pmid:14720063 |
Lee J et al. | Inpatient rehabilitation challenges in a quadrimembral amputee after bilateral hand transplantation. | 2011 | Am J Phys Med Rehabil | pmid:21765280 |
Laifer SA et al. | Pregnancy after cardiac transplantation. | 1994 | Am J Perinatol | pmid:7519426 |
Tulaci KG et al. | The effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model. | Am J Otolaryngol | pmid:27465503 | |
Knott PD et al. | Induction with T-cell receptor antibody leads to long-term laryngeal allograft function. | 2008 Nov-Dec | Am J Otolaryngol | pmid:19144301 |
Yang GS et al. | Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. | 2000 | Am J Otol | pmid:10912694 |
Pezze JL and Whiteman K | Transplantation's newest weapon FK 506. | 1991 | Am J Nurs | pmid:1716857 |
Taormina D et al. | Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. | 1992 | Am J Hosp Pharm | pmid:1373936 |
Min DI et al. | Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. | 1992 | Am J Hosp Pharm | pmid:1282779 |
Tacrolimus introduced for use in liver transplantation. | 1994 | Am J Hosp Pharm | pmid:7524317 | |
Przepiorka D et al. | Blood tacrolimus concentration unchanged by plasmapheresis. | 1994 | Am J Hosp Pharm | pmid:7524318 |
Matsunami H et al. | New technique for measuring tacrolimus concentrations in blood. | 1994 | Am J Hosp Pharm | pmid:7510929 |
Heavner MS et al. | Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. | 2013 | Am J Health Syst Pharm | pmid:23943182 |
Curtin BF et al. | Unusually late-onset mycophenolate mofetil-related colitis. | 2014 | Am J Health Syst Pharm | pmid:25320135 |
Bonhomme-Faivre L et al. | Effect of the ABCB1 3435C>T polymorphism on tacrolimus concentrations and dosage requirements in liver transplant recipients. | 2009 | Am J Health Syst Pharm | pmid:19729569 |
Tacrolimus. | 2001 | Am J Health Syst Pharm | pmid:11794952 | |
Tsapepas DS et al. | Managing the atazanavir-tacrolimus drug interaction in a renal transplant recipient. | 2011 | Am J Health Syst Pharm | pmid:21200061 |
Myers AL et al. | Stability of tacrolimus injection diluted in 0.9% sodium chloride injection and stored in Excel bags. | 2016 | Am J Health Syst Pharm | pmid:27919876 |
Grouzmann E et al. | Misleading tacrolimus concentration value in blood taken from a catheter used for tacrolimus administration. | 2008 | Am J Health Syst Pharm | pmid:18216007 |