tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ku YM et al. | Compatibility of tacrolimus injection with cimetidine hydrochloride injection in 0.9% sodium chloride injection. | 1995 | Am J Health Syst Pharm | pmid:8528874 |
| Greanya ED et al. | Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen. | 2012 | Am J Health Syst Pharm | pmid:22215359 |
| Heavner MS et al. | Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. | 2013 | Am J Health Syst Pharm | pmid:23943182 |
| Curtin BF et al. | Unusually late-onset mycophenolate mofetil-related colitis. | 2014 | Am J Health Syst Pharm | pmid:25320135 |
| Bonhomme-Faivre L et al. | Effect of the ABCB1 3435C>T polymorphism on tacrolimus concentrations and dosage requirements in liver transplant recipients. | 2009 | Am J Health Syst Pharm | pmid:19729569 |
| Tacrolimus. | 2001 | Am J Health Syst Pharm | pmid:11794952 | |
| Utecht KN et al. | Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors. | 2006 | Am J Health Syst Pharm | pmid:17106006 |
| MacDonald AS and Sketris IS | Tacrolimus in transplantation. | 1995 | Am J Health Syst Pharm | pmid:7552906 |
| Tsapepas DS et al. | Managing the atazanavir-tacrolimus drug interaction in a renal transplant recipient. | 2011 | Am J Health Syst Pharm | pmid:21200061 |
| Myers AL et al. | Stability of tacrolimus injection diluted in 0.9% sodium chloride injection and stored in Excel bags. | 2016 | Am J Health Syst Pharm | pmid:27919876 |
| Grouzmann E et al. | Misleading tacrolimus concentration value in blood taken from a catheter used for tacrolimus administration. | 2008 | Am J Health Syst Pharm | pmid:18216007 |
| Kasper RC et al. | Anetoderma arising in cutaneous B-cell lymphoproliferative disease. | 2001 | Am J Dermatopathol | pmid:11285407 |
| Breuer K et al. | Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. | 2005 | Am J Clin Dermatol | pmid:15799678 |
| Kalavala M and Dohil MA | Calcineurin inhibitors in pediatric atopic dermatitis: a review of current evidence. | 2011 | Am J Clin Dermatol | pmid:21067248 |
| Patel TS et al. | Cancer concerns with topical immunomodulators in atopic dermatitis: overview of data and recommendations to clinicians. | 2007 | Am J Clin Dermatol | pmid:17645374 |
| Iskedjian M et al. | Topical calcineurin inhibitors in the treatment of atopic dermatitis: a meta-analysis of current evidence. | 2004 | Am J Clin Dermatol | pmid:15301573 |
| Tjioe M et al. | Topical macrolide immunomodulators: a role in the treatment of vitiligo? | 2006 | Am J Clin Dermatol | pmid:16489839 |
| Ingram JR et al. | Impact of topical calcineurin inhibitors on quality of life in patients with atopic dermatitis. | 2009 | Am J Clin Dermatol | pmid:19489656 |
| Reitamo S et al. | Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113647 |
| Wellington K and Jarvis B | Spotlight on topical pimecrolimus in atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113651 |