Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jackson Cullison SR and Siegfried EC | Paradoxic eczema in infants after heart transplantation. | 2018 | Pediatr Dermatol | pmid:29194735 |
Zhang H et al. | Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:28945011 |
Ayala E et al. | Haploidentical transplantation as a promising therapy for relapsed hemophagocytic lymphohistiocytosis in an older adult patient. | 2018 | Hematol Oncol Stem Cell Ther | pmid:27352259 |
Zaman M et al. | Application of quasi-emulsification and modified double emulsification techniques for formulation of tacrolimus microsponges. | 2018 | Int J Nanomedicine | pmid:30127605 |
Wang JL et al. | Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy. | 2018 | Biomater Sci | pmid:29850666 |
Ling G et al. | Mycophenolate Mofetil Alone and in Combination with Tacrolimus Inhibits the Proliferation of HT-29 Human Colonic Adenocarcinoma Cell Line and Might Interfere with Colonic Tumorigenesis. | 2018 | Anticancer Res. | pmid:29848681 |
Geng L et al. | Lower tacrolimus trough levels in the late period after living donor liver transplantation contribute to improvements in long-term clinical outcomes. | 2018 | HBPD INT | pmid:29807766 |
Grenzi PC et al. | Influence of immunosuppressive drugs on the CD30 molecule in kidney transplanted patients. | 2018 | Hum. Immunol. | pmid:29656112 |
Altwegg R et al. | Effectiveness and safety of anti-TNF therapy for inflammatory bowel disease in liver transplant recipients for primary sclerosing cholangitis: A nationwide case series. | 2018 | Dig Liver Dis | pmid:29655972 |
Freriksen JJM et al. | Placental disposition of the immunosuppressive drug tacrolimus in renal transplant recipients and in ex vivo perfused placental tissue. | 2018 | Eur J Pharm Sci | pmid:29655601 |
Udomkarnjananun S et al. | An Unusual Manifestation of Calcineurin Inhibitor-Induced Pain Syndrome in Kidney Transplantation: A Case Report and Literature Review. | 2018 | Am J Case Rep | pmid:29654227 |
Gupta AS et al. | Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant. | 2018 | Wounds | pmid:29481333 |
Romano P et al. | UPLC-MS/MS assay validation for tacrolimus quantitative determination in peripheral blood T CD4+ and B CD19+ lymphocytes. | 2018 | J Pharm Biomed Anal | pmid:29471254 |
Lloberas N et al. | Detection of a rare CYP3A4 variant in a transplant patient characterized by a tacrolimus poor metabolizer phenotype. | 2018 | Pharmacogenomics | pmid:29469606 |
Li Y and Feng X | Efficacy and safety of tacrolimus in systemic lupus erythematosus patients with refractory thrombocytopenia: a retrospective study. | 2018 | Lupus | pmid:28566017 |
Wojarski J et al. | Immunosuppressive Treatment and Its Effect on the Occurrence of Pneumocystis jiroveci, Mycoplasma pneumoniae, Chlamydophila pnemoniae, and Legionella pneumophila Infections/Colonizations Among Lung Transplant Recipients. | 2018 | Transplant. Proc. | pmid:30177108 |
Yoshizawa S et al. | Exosomal miRNA Signatures for Late-Onset Acute Graft-Versus-Host Disease in Allogenic Hematopoietic Stem Cell Transplantation. | 2018 | Int J Mol Sci | pmid:30142940 |
Lindström L et al. | Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study. | 2018 | Scand. J. Gastroenterol. | pmid:29301479 |
Schutte-Nutgen K et al. | Tacrolimus - Pharmacokinetic Considerations for Clinicians. | 2018 | Curr. Drug Metab. | pmid:29298646 |
Wang HD et al. | Desensitization and Prevention of Antibody-Mediated Rejection in Vascularized Composite Allotransplantation by Syngeneic Hematopoietic Stem Cell Transplantation. | 2018 | Transplantation | pmid:29298238 |