Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dury S et al. | Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study. | 2015 | BMC Pulm Med | pmid:26545860 |
Obayashi N et al. | Management of tacrolimus-associated food allergy after liver transplantation. | 2015 | Pediatr Int | pmid:26541649 |
Kwon M et al. | Bioequivalence of tacrolimus formulations with different dynamic solubility and in-vitro dissolution profiles. | 2015 | Arch. Pharm. Res. | pmid:24627339 |
Tang T et al. | Roles of the tacrolimus-dependent transcription factor IRF4 in acute rejection after liver transplantation. | 2015 | Int. Immunopharmacol. | pmid:26093273 |
Hu L et al. | Severe Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines. | 2015 | J Drugs Dermatol | pmid:26091390 |
Melilli E et al. | De novo use of a generic formulation of tacrolimus versus reference tacrolimus in kidney transplantation: evaluation of the clinical results, histology in protocol biopsies, and immunological monitoring. | 2015 | Transpl. Int. | pmid:26088437 |
Boukoum H et al. | BK and JC polyomavirus infections in Tunisian renal transplant recipients. | 2015 | J. Med. Virol. | pmid:25952258 |
Miura M et al. | Tacrolimus reduction with everolimus addition for calcineurin inhibitor-induced arteriolopathy in kidney allografts. | 2015 | Nephrology (Carlton) | pmid:26031588 |
Yagisawa T et al. | Arteriosclerosis in zero-time biopsy is a risk factor for tacrolimus-induced chronic nephrotoxicity. | 2015 | Nephrology (Carlton) | pmid:26031587 |
Lim EJ et al. | Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation. | 2015 | PLoS ONE | pmid:26390404 |
Shu WY et al. | Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population. | 2015 | Acta Pharmacol. Sin. | pmid:25891088 |
Baird K et al. | Imatinib mesylate for the treatment of steroid-refractory sclerotic-type cutaneous chronic graft-versus-host disease. | 2015 | Biol. Blood Marrow Transplant. | pmid:25771402 |
Shuker N et al. | Conversion from twice-daily to once-daily tacrolimus does not reduce intrapatient variability in tacrolimus exposure. | 2015 | Ther Drug Monit | pmid:25265255 |
Soto GAC et al. | Dose increase needed in most cystic fibrosis lung transplantation patients when changing from twice- to once-daily tacrolimus oral administration. | 2015 | Eur. J. Clin. Pharmacol. | pmid:25953736 |
Rojas L et al. | Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies. | 2015 | Pharmacogenomics J. | pmid:25201288 |
Daunton A et al. | A cutaneous presentation of a common condition. | 2015 | BMJ | pmid:26681202 |
Yang SS et al. | A single center, open-label, randomized pilot study to evaluate the safety and efficacy of tacrolimus modified release, Advagraf, versus tacrolimus twice daily, Prograf, in stable renal recipients (single). | 2015 | Transplant. Proc. | pmid:25891697 |
Ã…berg F et al. | Asymptomatic De Novo Inflammatory Bowel Disease Late After Liver Transplantation for Primary Sclerosing Cholangitis: A Case Report. | 2015 | Transplant. Proc. | pmid:26680092 |
Rojanathammanee L et al. | Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition. | 2015 | J Neuroinflammation | pmid:25889879 |
Hempen CM et al. | Hematocrit-independent recovery of immunosuppressants from DBS using heated flow-through desorption. | 2015 | Bioanalysis | pmid:26327182 |
Reig Mezquida JP et al. | Thrombotic microangiopathy associated with tacrolimus in lung transplantation. | 2015 | Arch. Bronconeumol. | pmid:25138798 |
Rajaganapathy BR et al. | Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. | 2015 | J. Urol. | pmid:25839382 |
Nagashima T and Minota S | Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. | 2015 | Rheumatology (Oxford) | pmid:25832615 |
Vollmar J et al. | Efficacy and safety of a conversion from the original tacrolimus and mycophenolate mofetil to the generics Tacpan and Mowel after liver transplantation. | 2015 | Drug Des Devel Ther | pmid:26604701 |
Yasuda S et al. | Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis: reply. | 2015 | Rheumatology (Oxford) | pmid:25832614 |
Wang YY et al. | Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. | 2015 | Protein Pept. Lett. | pmid:25267255 |
Adotama P et al. | Patient satisfaction with different treatment modalities for vitiligo. | 2015 | J. Am. Acad. Dermatol. | pmid:25773415 |
Cendales L et al. | Tacrolimus to Belatacept Conversion Following Hand Transplantation: A Case Report. | 2015 | Am. J. Transplant. | pmid:25773260 |
Singh N et al. | Extended release once a day tacrolimus. | 2015 | Curr Opin Organ Transplant | pmid:26536429 |
Mahajan R et al. | Co-localization of agminated congenital melanocytic nevi with vitiligo vulgaris: an unusual presentation. | 2015 | Int. J. Dermatol. | pmid:25039486 |
Zitelli K et al. | Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review. | 2015 | Int. J. Dermatol. | pmid:25039354 |
Guethoff S et al. | De novo sirolimus with low-dose tacrolimus versus full-dose tacrolimus with mycophenolate mofetil after heart transplantation--8-year results. | 2015 | J. Heart Lung Transplant. | pmid:25701373 |
Kim M et al. | Nail lichen striatus: report of seven cases and review of the literature. | 2015 | Int. J. Dermatol. | pmid:26474189 |
Cen J et al. | The new immunosuppressant, isogarcinol, binds directly to its target enzyme calcineurin, unlike cyclosporin A and tacrolimus. | 2015 | Biochimie | pmid:25701551 |
Ferjani H et al. | Tacrolimus and mycophenolate mofetil associations: Induction of oxidative stress or antioxidant effect? | 2015 | Hum Exp Toxicol | pmid:25645822 |
RodrÃguez-Perálvarez M et al. | Everolimus is safe within the first month after liver transplantation. | 2015 | Transpl. Immunol. | pmid:26392195 |
Knops N et al. | The functional implications of common genetic variation in CYP3A5 and ABCB1 in human proximal tubule cells. | 2015 | Mol. Pharm. | pmid:25590378 |
Pallet N et al. | Kidney transplant recipients carrying the CYP3A4*22 allelic variant have reduced tacrolimus clearance and often reach supratherapeutic tacrolimus concentrations. | 2015 | Am. J. Transplant. | pmid:25588704 |
Yoo MC et al. | Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients. | 2015 | Transplantation | pmid:25539464 |
Offer K et al. | Efficacy of tacrolimus/mycophenolate mofetil as acute graft-versus-host disease prophylaxis and the impact of subtherapeutic tacrolimus levels in children after matched sibling donor allogeneic hematopoietic cell transplantation. | 2015 | Biol. Blood Marrow Transplant. | pmid:25536217 |
Ramachandran R et al. | Role of Tacrolimus only therapy in modified Ponticelli regimen resistant idiopathic membranous glomerulonephritis. | 2015 | Nephrology (Carlton) | pmid:25535867 |
Kim SH et al. | Conversion of twice-daily to once-daily tacrolimus is safe in stable adult living donor liver transplant recipients. | 2015 | HBPD INT | pmid:26256081 |
Duvoux C et al. | Sustained virological response to antiviral therapy in a randomized trial of cyclosporine versus tacrolimus in liver transplant patients with recurrent hepatitis C infection. | 2015 | Ann. Transplant. | pmid:25588713 |
Hoerning A et al. | Pharmacodynamic monitoring of mammalian target of rapamycin inhibition by phosphoflow cytometric determination of p70S6 kinase activity. | 2015 | Transplantation | pmid:25099702 |
Valke LL et al. | Soluble CD30 does not predict late acute rejection or safe tapering of immunosuppression in renal transplantation. | 2015 | Transpl. Immunol. | pmid:25446808 |
Huang G et al. | Monitoring of polyomavirus BK replication and impact of preemptive immunosuppression reduction in renal-transplant recipients in China: a 5-year single-center analysis. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25445121 |
Spiekerkoetter E et al. | Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26177174 |
Mandelbrot DA et al. | Effect of Ramipril on Urinary Protein Excretion in Maintenance Renal Transplant Patients Converted to Sirolimus. | 2015 | Am. J. Transplant. | pmid:26176342 |
Guo CL et al. | Efficacy of Topical Tacrolimus for Erosive Oral Lichen Planus: A Meta-analysis. | 2015 | Chin. Med. Sci. J. | pmid:26960301 |
Apalla Z et al. | Psoriatic cheilitis: a report of 2 cases treated successfully with topical tacrolimus and a review of the literature. | 2015 | Actas Dermosifiliogr | pmid:26164836 |