tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lyon CC et al. | Recalcitrant pyoderma gangrenosum treated with systemic tacrolimus. | 1999 | Br. J. Dermatol. | pmid:10233300 |
| Vente C et al. | Erosive mucosal lichen planus: response to topical treatment with tacrolimus. | 1999 | Br. J. Dermatol. | pmid:10233234 |
| Johnston A and Holt DW | Therapeutic drug monitoring of immunosuppressant drugs. | 1999 | Br J Clin Pharmacol | pmid:10233195 |
| Uno T et al. | Pharmacokinetic advantages of a newly developed tacrolimus oil-in-water-type emulsion via the enteral route. | 1999 | Lipids | pmid:10230718 |
| Göthel SF and Marahiel MA | Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts. | 1999 | Cell. Mol. Life Sci. | pmid:10228556 |
| Torocsik HV et al. | FK506-induced leukoencephalopathy in children with organ transplants. | 1999 | Neurology | pmid:10227644 |
| Taylor DO et al. | A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus. | 1999 | J. Heart Lung Transplant. | pmid:10226898 |
| Charco R et al. | Serum cholesterol changes in long-term survivors of liver transplantation: a comparison between cyclosporine and tacrolimus therapy. | 1999 | Liver Transpl Surg | pmid:10226111 |
| Herr I et al. | FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. | 1999 | Brain Res. | pmid:10224298 |
| Ferrari D et al. | P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells. | 1999 | J. Biol. Chem. | pmid:10224077 |
| Green MD and Michaels MG | Tacrolimus: effects and side effects. | 1999 | Pediatr. Infect. Dis. J. | pmid:10223694 |
| Knoll GA and Bell RC | Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials. | 1999 | BMJ | pmid:10213717 |
| Jani A et al. | Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve. | 1999 | Hum. Gene Ther. | pmid:10210146 |
| Lütkes P et al. | [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. | 1999 | Zentralbl Chir | pmid:10209841 |
| Cetinkale O et al. | Modulating the functions of neutrophils and lipid peroxidation by FK506 in a rat model of thermal injury. | 1999 | Burns | pmid:10208383 |
| Hortelano S et al. | Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. | 1999 | Br. J. Pharmacol. | pmid:10205001 |
| Nagasaki Y et al. | Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. | 1999 | Pediatr. Res. | pmid:10203136 |
| Sloper CM et al. | Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. | 1999 | Ophthalmology | pmid:10201592 |
| De Lima JJ et al. | Effects of FK506 in rat and human resistance arteries. | 1999 | Kidney Int. | pmid:10201018 |
| Mollison KW et al. | Discovery of ascomycin analogs with potent topical but weak systemic activity for treatment of inflammatory skin diseases. | 1998 | Curr. Pharm. Des. | pmid:10197049 |