tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Cervical Intraepithelial Neoplasia D018290 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Porokeratosis D017499 1 associated lipids
Lentigo D007911 1 associated lipids
Mutism D009155 1 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Meningitis, Fungal D016921 1 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Flaviviridae Infections D018178 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Antonini TM et al. Therapy with boceprevir or telaprevir in HIV/hepatitis C virus co-infected patients to treat recurrence of hepatitis C virus infection after liver transplantation. 2015 AIDS pmid:25387314
Nowak P et al. Follow-up of antiretroviral treatment in liver transplant recipients with primary and chronic HIV type 1 infection. 2003 AIDS Res. Hum. Retroviruses pmid:12581512
Sklar EM Post-transplant neurotoxicity: what role do calcineurin inhibitors actually play? 2006 AJNR Am J Neuroradiol pmid:16971594
Bargalló N et al. Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy. 2000 AJNR Am J Neuroradiol pmid:10730638
Bartynski WS et al. Etiology of cortical and white matter lesions in cyclosporin-A and FK-506 neurotoxicity. 2001 Nov-Dec AJNR Am J Neuroradiol pmid:11733324
Bartynski WS et al. Pretransplantation conditioning influence on the occurrence of cyclosporine or FK-506 neurotoxicity in allogeneic bone marrow transplantation. 2004 AJNR Am J Neuroradiol pmid:14970028
Bartynski WS et al. Posterior reversible encephalopathy syndrome after solid organ transplantation. 2008 AJNR Am J Neuroradiol pmid:18272559
Schuuring J et al. Severe tacrolimus leukoencephalopathy after liver transplantation. 2003 Nov-Dec AJNR Am J Neuroradiol pmid:14625238
Oliverio PJ et al. Reversible tacrolimus-induced neurotoxicity isolated to the brain stem. 2000 AJNR Am J Neuroradiol pmid:10954277
Appignani BA et al. Neuroimaging findings in patients on immunosuppressive therapy: experience with tacrolimus toxicity. 1996 AJR Am J Roentgenol pmid:8623651
Firpi RJ et al. Sirolimus-induced hyperlipidaemia in liver transplant recipients is not dose-dependent. 2004 Aliment. Pharmacol. Ther. pmid:15113371
Herrlinger KR et al. Infliximab as rescue medication for patients with severe ulcerative/indeterminate colitis refractory to tacrolimus. 2010 Aliment. Pharmacol. Ther. pmid:20175769
Hisanaga Y et al. Implication of nitric oxide synthase activity in the genesis of water immersion stress-induced gastric lesions in rats: the protective effects of FK506. 1996 Aliment. Pharmacol. Ther. pmid:8971291
Trotter JF et al. Effect of hepatitis C infection on tacrolimus doses and blood levels in liver transplantation recipients. 2005 Aliment. Pharmacol. Ther. pmid:15963078
Hoshino H et al. Effects of FK506 on an experimental model of colitis in rats. 1995 Aliment. Pharmacol. Ther. pmid:7544633
Liberal R et al. Expert clinical management of autoimmune hepatitis in the real world. 2017 Aliment. Pharmacol. Ther. pmid:28004405
Segal JP et al. Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm. 2017 Aliment. Pharmacol. Ther. pmid:28008631
Yamamoto T et al. Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis--authors' reply. 2016 Aliment. Pharmacol. Ther. pmid:27040167
Taylor KM and Sparrow MP Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis. 2016 Aliment. Pharmacol. Ther. pmid:27040166
Nakase H et al. Cytomegalovirus affects clinical outcome of infliximab in ulcerative colitis refractory to tacrolimus. 2010 Aliment. Pharmacol. Ther. pmid:20636704