| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thrombosis | D013927 | 49 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Hemorrhage | D006470 | 15 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Femur Head Necrosis | D005271 | 5 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Eye Diseases | D005128 | 12 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dickerson JA et al. | Tacrolimus and sirolimus in capillary dried blood spots allows for remote monitoring. | 2015 | Pediatr Transplant | pmid:25414084 |
| Rivelli RF et al. | Early withdrawal of calcineurin inhibitor from a sirolimus-based immunosuppression stabilizes fibrosis and the transforming growth factor-β signalling pathway in kidney transplant. | 2015 | Nephrology (Carlton) | pmid:25404086 |
| Jahan A et al. | Clinical efficacy and pharmacokinetics of tacrolimus in children with steroid-resistant nephrotic syndrome. | 2015 | Pediatr. Nephrol. | pmid:26135137 |
| Marquezan MC et al. | Effect of Topical Tacrolimus in the Treatment of Thygeson's Superficial Punctate Keratitis. | 2015 | Am. J. Ophthalmol. | pmid:26133248 |
| Birdwell KA et al. | Assessment of arterial stiffness using pulse wave velocity in tacrolimus users the first year post kidney transplantation: a prospective cohort study. | 2015 | BMC Nephrol | pmid:26133166 |
| Cury Martins J et al. | Topical tacrolimus for atopic dermatitis. | 2015 | Cochrane Database Syst Rev | pmid:26132597 |
| Izumi Y et al. | Two cases of refractory polymyositis accompanied with steroid myopathy. | 2015 | Mod Rheumatol | pmid:24533547 |
| Huang X and Xu B | Efficacy and Safety of Tacrolimus versus Pimecrolimus for the Treatment of Atopic Dermatitis in Children: A Network Meta-Analysis. | 2015 | Dermatology (Basel) | pmid:26043855 |
| Milam EC et al. | Treatment of Scarring Alopecia in Discoid Variant of Chronic Cutaneous Lupus Erythematosus With Tacrolimus Lotion, 0.3. | 2015 | JAMA Dermatol | pmid:26039539 |
| Argudo A et al. | Liver Transplant Patient Carriers of Polymorphism Cyp3a5*1 Donors May Need More Doses of Tacrolimus From the First Month After Transplantation. | 2015 | Transplant. Proc. | pmid:26518936 |
| Xia Z et al. | Refractory Dyslipidemia After Liver Transplant: Case Study With Successive Histologic Investigations. | 2015 | Exp Clin Transplant | pmid:25924105 |
| Zheng L et al. | Simultaneous determination of cortisol, cortisone, 6β-hydroxycortisol and 6β-hydroxycortisone by HPLC. | 2015 | J Chromatogr Sci | pmid:25628347 |
| Gupta G et al. | Safe Conversion From Tacrolimus to Belatacept in High Immunologic Risk Kidney Transplant Recipients With Allograft Dysfunction. | 2015 | Am. J. Transplant. | pmid:25988397 |
| Söderlund C and Rådegran G | Safety and efficacy of the switch to generic mycophenolate mofetil and tacrolimus in heart transplant patients. | 2015 | Clin Transplant | pmid:25981927 |
| Yahng SA et al. | A well-tolerated regimen of 800 cGy TBI-fludarabine-busulfan-ATG for reliable engraftment after unmanipulated haploidentical peripheral blood stem cell transplantation in adult patients with acute myeloid leukemia. | 2015 | Biol. Blood Marrow Transplant. | pmid:25300871 |
| van Boekel GA et al. | Limited sampling strategy for prolonged-release tacrolimus in renal transplant patients by use of the dried blood spot technique. | 2015 | Eur. J. Clin. Pharmacol. | pmid:25980838 |
| de Jonge H et al. | The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients. | 2015 | Pharmacogenomics J. | pmid:25287072 |
| Lin YK et al. | Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. | 2015 | PLoS ONE | pmid:26355594 |
| Andrews LM et al. | Dosing algorithms for initiation of immunosuppressive drugs in solid organ transplant recipients. | 2015 | Expert Opin Drug Metab Toxicol | pmid:25865963 |
| Murata M | Prophylactic and therapeutic treatment of graft-versus-host disease in Japan. | 2015 | Int. J. Hematol. | pmid:25864188 |
| Cuervas-Mons V et al. | Impact of tacrolimus and mycophenolate mofetil regimen vs. a conventional therapy with steroids on cardiovascular risk in liver transplant patients. | 2015 | Clin Transplant | pmid:25924549 |
| Hategan A and Bourgeois JA | Tacrolimus neurotoxicity and the role of the Renin-Angiotensin system. | 2015 | J Neuropsychiatry Clin Neurosci | pmid:25923858 |
| Li JS et al. | Angiopoietin-Like-4, a Potential Target of Tacrolimus, Predicts Earlier Podocyte Injury in Minimal Change Disease. | 2015 | PLoS ONE | pmid:26352670 |
| Lin S et al. | Interleukin-2 receptor antagonist therapy leads to increased tacrolimus levels after kidney transplantation. | 2015 | Ther Drug Monit | pmid:25162212 |
| Jiang H et al. | An acyltransferase domain of FK506 polyketide synthase recognizing both an acyl carrier protein and coenzyme A as acyl donors to transfer allylmalonyl and ethylmalonyl units. | 2015 | FEBS J. | pmid:25865045 |
| Josephson MA et al. | American society of Nephrology Quiz and Questionnaire 2014: transplantation. | 2015 | Clin J Am Soc Nephrol | pmid:25862775 |
| Liu S et al. | Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study. | 2015 | BMC Nephrol | pmid:26637482 |
| Watanabe K et al. | The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease. | 2015 | Mol Brain | pmid:26637371 |
| Sigurgeirsson B et al. | Safety and efficacy of pimecrolimus in atopic dermatitis: a 5-year randomized trial. | 2015 | Pediatrics | pmid:25802354 |
| Kurita T et al. | The efficacy of calcineurin inhibitors for the treatment of interstitial lung disease associated with polymyositis/dermatomyositis. | 2015 | Lupus | pmid:25297551 |
| Birdwell KA et al. | Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing. | 2015 | Clin. Pharmacol. Ther. | pmid:25801146 |
| Shokati T et al. | Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS. | 2015 | J Vis Exp | pmid:26575262 |
| Furie R et al. | Lessons Learned From the Clinical Trials of Novel Biologics and Small Molecules in Lupus Nephritis. | 2015 | Semin. Nephrol. | pmid:26573553 |
| Abe Y et al. | Successful Management of Lupus Nephritis with High Titers of Myeloperoxidase Anti-Neutrophil Cytoplasmic Antibodies Using Tacrolimus. | 2015 | Intern. Med. | pmid:26568012 |
| William BM and de Lima M | Sirolimus plus calcineurin inhibitors and methotrexate: is more necessarily better? | 2015 | Leuk. Lymphoma | pmid:25065702 |
| Gu L et al. | A retrospective study to compare the use of tacrolimus and cyclosporine in combination with adriamycin in post-transplant liver cancer patients. | 2015 | Cell Biochem. Biophys. | pmid:25287673 |
| Ambrosioni J et al. | Role of rhinovirus load in the upper respiratory tract and severity of symptoms in lung transplant recipients. | 2015 | J. Clin. Virol. | pmid:25728070 |
| Marcus EA et al. | Successful term pregnancy in an intestine-pancreas transplant recipient with chronic graft dysfunction and parenteral nutrition dependence: a case report. | 2015 | Transplant. Proc. | pmid:25724255 |
| Youbin Z et al. | Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Gene Overexpression Prolongs the Survival of Rat Allogeneic Heart Allografts. | 2015 | Transplant. Proc. | pmid:26518962 |
| Schwarz C et al. | Tacrolimus, Mycophenolate Mofetil, and Low-Dose Steroids With or Without Interleukin-2 Receptor Antibody Induction Therapy: A Retrospective Cohort Analysis. | 2015 | Transplant. Proc. | pmid:26518948 |
| Ko MS et al. | Tacrolimus therapy causes hepatotoxicity in patients with a history of liver disease. | 2015 | Int J Clin Pharmacol Ther | pmid:25740263 |
| Townamchai N et al. | A Simple Novel Technique to Estimate Tacrolimus Dosages During the Early Post Kidney Transplantation Period. | 2015 | Transplant. Proc. | pmid:26518946 |
| Cotton D | Celebrating the ACP centennial: from the Annals archive. | 2015 | Ann. Intern. Med. | pmid:25560715 |
| Zhao L et al. | Bovine serum albumin nanoparticles for delivery of tacrolimus to reduce its kidney uptake and functional nephrotoxicity. | 2015 | Int J Pharm | pmid:25681723 |
| Ramesh M et al. | A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells. | 2015 | J. Biol. Chem. | pmid:25681440 |
| Pascher A et al. | Protein kinase C inhibitor sotrastaurin in de novo liver transplant recipients: a randomized phase II trial. | 2015 | Am. J. Transplant. | pmid:25677074 |
| Tavira B et al. | The donor ABCB1 (MDR-1) C3435T polymorphism is a determinant of the graft glomerular filtration rate among tacrolimus treated kidney transplanted patients. | 2015 | J. Hum. Genet. | pmid:25673014 |
| Wang Y et al. | Justification of noninferiority margin: methodology considerations in an exposure-response analysis. | 2015 | Clin. Pharmacol. Ther. | pmid:25670256 |
| Kikuchi T et al. | Outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for multiple myeloma. | 2015 | Int. J. Hematol. | pmid:26440970 |
| Dai DS et al. | Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. | 2015 | Am. J. Nephrol. | pmid:26439819 |
| Ceberio I et al. | Sirolimus, tacrolimus and low-dose methotrexate based graft-versus-host disease prophylaxis after non-ablative or reduced intensity conditioning in related and unrelated donor allogeneic hematopoietic cell transplant. | 2015 | Leuk. Lymphoma | pmid:24913499 |
| Aouam K et al. | Development of Limited Sampling Strategies for the Estimation of Tacrolimus Area Under the Curve in Adult Kidney Transplant Recipients According to the Posttransplantation Time. | 2015 | Ther Drug Monit | pmid:25627405 |
| Farhangian ME et al. | Treatment of Alopecia Areata in the United States: A Retrospective Cross-Sectional Study. | 2015 | J Drugs Dermatol | pmid:26355621 |
| Kawahara T et al. | The role of NFATc1 in prostate cancer progression: cyclosporine A and tacrolimus inhibit cell proliferation, migration, and invasion. | 2015 | Prostate | pmid:25631176 |
| Palanisamy AP et al. | Induction therapy: clinical and quality of life outcomes in aged renal transplant recipients. | 2015 | Clin Transplant | pmid:25557762 |
| Luger T et al. | Pimecrolimus in atopic dermatitis: consensus on safety and the need to allow use in infants. | 2015 | Pediatr Allergy Immunol | pmid:25557211 |
| Tedesco-Silva H et al. | Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus and Reduced Tacrolimus Doses. | 2015 | Am. J. Transplant. | pmid:25988935 |
| Al-Harbi NO et al. | Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats. | 2015 | J Renin Angiotensin Aldosterone Syst | pmid:24737642 |
| Jung JW et al. | Long-term result of maintenance treatment with tacrolimus ointment in chronic ocular graft-versus-host disease. | 2015 | Am. J. Ophthalmol. | pmid:25498356 |
| Lawrence MC et al. | NFAT targets signaling molecules to gene promoters in pancreatic β-cells. | 2015 | Mol. Endocrinol. | pmid:25496032 |
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| Denardi LB et al. | Synergistic effects of tacrolimus and azole antifungal compounds in fluconazole-susceptible and fluconazole-resistant Candida glabrata isolates. | 2015 | Braz. J. Microbiol. | pmid:26221097 |
| Scholz FM et al. | Focal metatarsal fistulae syndrome affecting a greyhound dog successfully treated with topical 0.1% tacrolimus ointment. | 2015 | Vet. Dermatol. | pmid:26216245 |
| Koster RA et al. | The performance of five different dried blood spot cards for the analysis of six immunosuppressants. | 2015 | Bioanalysis | pmid:26045003 |
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| Misra DP et al. | Pulmonary co-infection with Nocardia and Aspergillus in a patient with adult-onset Still's disease receiving steroids and tacrolimus. | 2014 | BMJ Case Rep | pmid:25398925 |
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| Jain A et al. | Delayed introduction of tacrolimus postliver transplant with intravenous mycophenolate mofetil preserves renal function without incurring rejection. | 2014 | Transplantation | pmid:25285953 |
| Protic M et al. | The effectiveness and safety of rescue treatments in 108 patients with steroid-refractory ulcerative colitis with sequential rescue therapies in a subgroup of patients. | 2014 | J Crohns Colitis | pmid:24908178 |
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| Lin BW et al. | Effect of 0.025% FK-506 eyedrops on botulinum toxin B-induced mouse dry eye. | 2014 | Invest. Ophthalmol. Vis. Sci. | pmid:25491293 |
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