Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mayba JN and Gooderham MJ | Review of Atopic Dermatitis and Topical Therapies. | J Cutan Med Surg | pmid:28300440 | |
Elloudi S et al. | [Frontal fibrosing alopecia: A prospective study of 20Â cases]. | Ann Dermatol Venereol | pmid:28258757 | |
Payabvash S et al. | Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. | J Postgrad Med | pmid:25370549 | |
Akoglu H et al. | Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors. | J. Nephrol. | pmid:23147686 | |
pmid:19200227 | ||||
Bethke G et al. | Swiss Dent J | pmid:28639684 | ||
Luger T et al. | Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs to a new treatment algorithm. | Eur J Dermatol | pmid:24185493 | |
Park J et al. | Persistent generalized lichen nitidus successfully treated with 0.03% tacrolimus ointment. | Eur J Dermatol | pmid:24184632 | |
Henrique Pinto C et al. | Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation. | Braz J Infect Dis | pmid:27643978 | |
Fernández C et al. | Kidney transplantation from HLA-incompatible live donors: Efficiency and outcome of 32 patients after desensitisation. | Nefrologia | pmid:28734583 | |
Menéndez Valladares P et al. | [Increased lipoprotein(a) in a paediatric patient associated with nephrotic syndrome]. | Clin Investig Arterioscler | pmid:27623226 | |
Errichetti E et al. | Annular elastolytic giant cell granuloma treated with topical pimecrolimus. | Indian J Dermatol Venereol Leprol | pmid:25201861 | |
Sathyan S et al. | Prevention of recurrent episodes of rhabdomyolysis with tacrolimus in a transplant recipient with myopathy. | Am J Ther | pmid:23429166 | |
Huang CT et al. | Higher Variability of Tacrolimus Trough Level Increases Risk of Acute Rejection in Kidney Transplant Recipients. | Transplant. Proc. | pmid:27569931 | |
Ge J et al. | Impact of FOXP3 Polymorphisms on the Blood Level of Tacrolimus in Renal Transplant Recipients. | Transplant. Proc. | pmid:27569929 | |
Yigitaslan S et al. | The Effect of P-Glycoprotein Inhibition and Activation on the Absorption and Serum Levels of Cyclosporine and Tacrolimus in Rats. | Adv Clin Exp Med | pmid:27627555 | |
Kathuria S et al. | Segmental vitiligo: a randomized controlled trial to evaluate efficacy and safety of 0.1% tacrolimus ointment vs 0.05% fluticasone propionate cream. | Indian J Dermatol Venereol Leprol | pmid:22199063 | |
Hirohata A et al. | Oral tacrolimus for the treatment of generalized morphea. | Eur J Dermatol | pmid:26679400 | |
Ortiz de Frutos FJ | [New horizons in the treatment of atopic dermatitis]. | Allergol Immunopathol (Madr) | pmid:11988144 | |
Gómez-Sánchez ME et al. | Intralymphatic Histiocytosis: A Report of 2 Cases. | Actas Dermosifiliogr | pmid:28256202 | |
López-Oliva MO et al. | Switch to belatacept in kidney graft recipients. | Nefrologia | pmid:28233569 | |
Sarvary E et al. | De novo Prograf versus de novo Advagraf: are trough level profile curves similar? | Transplant. Proc. | pmid:25131131 | |
Borda B et al. | Early histopathological changes in new-onset diabetes after kidney transplantation. | Transplant. Proc. | pmid:25131129 | |
Tulaci KG et al. | The effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model. | Am J Otolaryngol | pmid:27465503 | |
Cakici O et al. | Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus. | An Bras Dermatol | pmid:28300917 | |
Alokaily F et al. | Takayasu's arteritis and liver transplantation: Association and implications. | Saudi J Gastroenterol | pmid:26458863 | |
pmid:9123237 | ||||
Park JS et al. | Combinatory treatment using tacrolimus and a STAT3 inhibitor regulate Treg cells and plasma cells. | Int J Immunopathol Pharmacol | pmid:29873267 | |
Ülkümen PK et al. | Annular lichenoid dermatitis of youth in a 15-year-old boy: Topical tacrolimus as a treatment option. | Indian J Dermatol Venereol Leprol | pmid:27279324 | |
pmid:10773614 | ||||
Takahashi Y et al. | Pharmacokinetic Profile of Twice- and Once-daily Tacrolimus in Pediatric Kidney Transplant Recipients. | Transplant. Proc. | pmid:28104153 | |
Shi Y et al. | Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. | Transplant. Proc. | pmid:28104150 | |
Pan D et al. | Tacrolimus-associated Diffuse Gastrointestinal Ulcerations and Pathergy: A Case Report. | Transplant. Proc. | pmid:28104141 | |
Ash MM and Jolly PS | A Case Report of the Resolution of Multiple Recalcitrant Verrucae in a Renal Transplant Recipient After a Mycophenolate Mofetil Dose Reduction. | Transplant. Proc. | pmid:28104140 | |
Nayeri A et al. | Acute Calcineurin Inhibitor Nephrotoxicity Secondary to Turmeric Intake: A Case Report. | Transplant. Proc. | pmid:28104136 | |
Tahir W et al. | Diffuse Alveolar haemorrhage: a fatal complication after alemtuzumab induction therapy in renal transplantation. | Transplant. Proc. | pmid:25645795 | |
Jiménez-Pérez M et al. | Everolimus plus mycophenolate mofetil as initial immunosuppression in liver transplantation. | Transplant. Proc. | pmid:25645779 | |
Polanco N et al. | Everolimus-based immunosuppression therapy for BK virus nephropathy. | Transplant. Proc. | pmid:25645770 | |
Britto-Williams P and Pansare M | Management of chronic idiopathic urticaria in childhood: are we on the same page? | J Allergy Clin Immunol Pract | pmid:24565627 | |
Nunokawa T et al. | Late-onset scleroderma renal crisis induced by tacrolimus and prednisolone: a case report. | Am J Ther | pmid:22836123 | |
Nojima M et al. | Immunosuppression Modification by Everolimus With Minimization of Calcineurin Inhibitors Recovers Kidney Graft Function Even in Patients With Very Late Conversion and Also With Poor Graft Function. | Transplant. Proc. | pmid:28104155 | |
Paul GM et al. | Qualitative analysis of the deposit of collagen in bladder suture of rats treated with tacrolimus combined with mycophenolate-mofetil. | Int Braz J Urol | pmid:24856494 | |
López-Vilella R et al. | Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor. | Transplant. Proc. | pmid:25645789 | |
Tinoco R et al. | [A case of de novo inflammatory bowel disease after liver transplantation for cryptogenic cirrhosis]. | Gastroenterol Hepatol | pmid:26321322 | |
Mori F et al. | Increase of natural killer cells in children with liver transplantation-acquired food allergy. | Allergol Immunopathol (Madr) | pmid:29456038 | |
Hoverson K et al. | Dermestid Dermatitis in a 2-Year-Old Girl: Case Report and Review of the Literature. | Pediatr Dermatol | pmid:26250481 | |
pmid:28590598 | ||||
Torres A et al. | Mineral metabolism disorders, vertebral fractures and aortic calcifications in stable kidney transplant recipients: The role of gender (EMITRAL study). | Nefrologia | pmid:27133898 | |
pmid:28422431 | ||||
Al-Amri AM et al. | Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. | Middle East Afr J Ophthalmol | pmid:26957853 |