Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:8615615 | ||||
Mayba JN and Gooderham MJ | Review of Atopic Dermatitis and Topical Therapies. | J Cutan Med Surg | pmid:28300440 | |
Elloudi S et al. | [Frontal fibrosing alopecia: A prospective study of 20Â cases]. | Ann Dermatol Venereol | pmid:28258757 | |
Payabvash S et al. | Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. | J Postgrad Med | pmid:25370549 | |
Akoglu H et al. | Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors. | J. Nephrol. | pmid:23147686 | |
pmid:19200227 | ||||
Qu W et al. | Correlation Between Immunosuppressive Therapy and CD4(+) T-Cell Intracellular Adenosine Triphosphate Levels in Liver Transplant Recipients. | Transplant. Proc. | pmid:27569951 | |
Mlinšek G et al. | The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. | Clin. Nephrol. | pmid:28655393 | |
Bonatti HJR et al. | Clostridium difficile-Associated Colitis Post-Transplant Is Not Associated with Elevation of Tacrolimus Concentrations. | Surg Infect (Larchmt) | pmid:28650734 | |
Bethke G et al. | Swiss Dent J | pmid:28639684 | ||
Luger T et al. | Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs to a new treatment algorithm. | Eur J Dermatol | pmid:24185493 | |
Henrique Pinto C et al. | Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation. | Braz J Infect Dis | pmid:27643978 | |
Fernández C et al. | Kidney transplantation from HLA-incompatible live donors: Efficiency and outcome of 32 patients after desensitisation. | Nefrologia | pmid:28734583 | |
Liendo VL et al. | Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children. | Arq Bras Oftalmol | pmid:28954018 | |
Johnson JL et al. | Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis. | Pediatr Dermatol | pmid:23535023 | |
Errichetti E et al. | Annular elastolytic giant cell granuloma treated with topical pimecrolimus. | Indian J Dermatol Venereol Leprol | pmid:25201861 | |
Sathyan S et al. | Prevention of recurrent episodes of rhabdomyolysis with tacrolimus in a transplant recipient with myopathy. | Am J Ther | pmid:23429166 | |
Moreno Gonzales M et al. | Sublingual Tacrolimus in Liver Transplantation: A Valid Option? | Transplant. Proc. | pmid:27569953 | |
Ciancio G et al. | Pilot Randomized Trial of Tacrolimus/Everolimus vs Tacrolimus/Enteric-Coated Mycophenolate Sodium in Adult, Primary Kidney Transplant Recipients at a Single Center. | Transplant. Proc. | pmid:27569936 | |
Huang CT et al. | Higher Variability of Tacrolimus Trough Level Increases Risk of Acute Rejection in Kidney Transplant Recipients. | Transplant. Proc. | pmid:27569931 | |
Ge J et al. | Impact of FOXP3 Polymorphisms on the Blood Level of Tacrolimus in Renal Transplant Recipients. | Transplant. Proc. | pmid:27569929 | |
Hirohata A et al. | Oral tacrolimus for the treatment of generalized morphea. | Eur J Dermatol | pmid:26679400 | |
Ortiz de Frutos FJ | [New horizons in the treatment of atopic dermatitis]. | Allergol Immunopathol (Madr) | pmid:11988144 | |
Gómez-Sánchez ME et al. | Intralymphatic Histiocytosis: A Report of 2 Cases. | Actas Dermosifiliogr | pmid:28256202 | |
López-Oliva MO et al. | Switch to belatacept in kidney graft recipients. | Nefrologia | pmid:28233569 | |
Cakici O et al. | Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus. | An Bras Dermatol | pmid:28300917 | |
pmid:9123014 | ||||
Ming M et al. | Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response. | Photochem. Photobiol. | pmid:25039758 | |
Park JS et al. | Combinatory treatment using tacrolimus and a STAT3 inhibitor regulate Treg cells and plasma cells. | Int J Immunopathol Pharmacol | pmid:29873267 | |
pmid: | ||||
Takahashi Y et al. | Pharmacokinetic Profile of Twice- and Once-daily Tacrolimus in Pediatric Kidney Transplant Recipients. | Transplant. Proc. | pmid:28104153 | |
Shi Y et al. | Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. | Transplant. Proc. | pmid:28104150 | |
Tahir W et al. | Diffuse Alveolar haemorrhage: a fatal complication after alemtuzumab induction therapy in renal transplantation. | Transplant. Proc. | pmid:25645795 | |
Jiménez-Pérez M et al. | Everolimus plus mycophenolate mofetil as initial immunosuppression in liver transplantation. | Transplant. Proc. | pmid:25645779 | |
Polanco N et al. | Everolimus-based immunosuppression therapy for BK virus nephropathy. | Transplant. Proc. | pmid:25645770 | |
Nunokawa T et al. | Late-onset scleroderma renal crisis induced by tacrolimus and prednisolone: a case report. | Am J Ther | pmid:22836123 | |
Nojima M et al. | Immunosuppression Modification by Everolimus With Minimization of Calcineurin Inhibitors Recovers Kidney Graft Function Even in Patients With Very Late Conversion and Also With Poor Graft Function. | Transplant. Proc. | pmid:28104155 | |
Paul GM et al. | Qualitative analysis of the deposit of collagen in bladder suture of rats treated with tacrolimus combined with mycophenolate-mofetil. | Int Braz J Urol | pmid:24856494 | |
López-Vilella R et al. | Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor. | Transplant. Proc. | pmid:25645789 | |
Tinoco R et al. | [A case of de novo inflammatory bowel disease after liver transplantation for cryptogenic cirrhosis]. | Gastroenterol Hepatol | pmid:26321322 | |
pmid:22935463 | ||||
pmid:28951508 | ||||
pmid:28761977 | ||||
Hoverson K et al. | Dermestid Dermatitis in a 2-Year-Old Girl: Case Report and Review of the Literature. | Pediatr Dermatol | pmid:26250481 | |
pmid:28590598 | ||||
Torres A et al. | Mineral metabolism disorders, vertebral fractures and aortic calcifications in stable kidney transplant recipients: The role of gender (EMITRAL study). | Nefrologia | pmid:27133898 | |
pmid:28422431 | ||||
Malik S et al. | Disseminated infection in a kidney-pancreas transplant recipient: A case report and review of the literature. | Saudi J Kidney Dis Transpl | pmid:27900974 | |
Tan GF et al. | Anogenital epidermolytic acanthomas: effective treatment of pruritus with 0.1% tacrolimus ointment. | Dermatol Ther | pmid:24703270 | |
Al-Amri AM et al. | Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. | Middle East Afr J Ophthalmol | pmid:26957853 |