| MeSH term | MeSH ID | Detail |
|---|---|---|
| IgG Deficiency | D017099 | 1 associated lipids |
| Deltaretrovirus Infections | D006800 | 1 associated lipids |
| Hepatopulmonary Syndrome | D020065 | 1 associated lipids |
| Herpes Labialis | D006560 | 1 associated lipids |
| End Stage Liver Disease | D058625 | 1 associated lipids |
| Nocturnal Myoclonus Syndrome | D020189 | 1 associated lipids |
| Rotavirus Infections | D012400 | 1 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
| Pseudohypoaldosteronism | D011546 | 1 associated lipids |
| Dendritic Cell Sarcoma, Interdigitating | D054739 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Platz KP et al. | Causes of death following liver transplantation in FK 506- and cyclosporine-treated patients. | 1994 | Transplant. Proc. | pmid:7527952 |
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| Felldin M et al. | Rescue therapy with Tacrolimus (FK506) in renal transplant recipients--a multicenter analysis. | 1995 | Transplant. Proc. | pmid:8540032 |
| Kahan BD | Cyclosporine: the base for immunosuppressive therapy--present and future. | 1993 | Transplant. Proc. | pmid:7679819 |
| Bersztel A et al. | Deoxyspergualin is synergistic with cyclosporin A, but not with FK506 in a rat heart allograft transplantation model. | 1995 | Transplant. Proc. | pmid:8540095 |
| Tze WJ et al. | Prolongation of pig islet xenograft survival in rats by local immunosuppression with FK 506. | 1994 | Transplant. Proc. | pmid:7513471 |
| Starzl TE | FK 506 versus cyclosporine. | 1993 | Transplant. Proc. | pmid:7679820 |
| Fukuzaki T et al. | Nonvascularized islet xenograft rejection in a mouse-to-rat combination where the vascularized heart is rapidly rejected. | 1994 | Transplant. Proc. | pmid:7513472 |
| Yabuuchi H et al. | Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. | 1991 | Transplant. Proc. | pmid:1703718 |
| First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. | 1991 | Transplant. Proc. | pmid:1721253 | |
| McCauley J et al. | The effects of FK 506 on renal function after liver transplantation. | 1990 | Transplant. Proc. | pmid:1689887 |
| Kang Y et al. | Acute hemodynamic effects of FK 506 during and after orthotopic liver transplantation. | 1990 | Transplant. Proc. | pmid:1689889 |
| Facundo C et al. | Results of a triple induction regime with tacrolimus, mycophenolate mofetil, and prednisone in renal transplantation. | 2002 | Transplant. Proc. | pmid:11959203 |
| McDiarmid S et al. | One hundred children treated with tacrolimus after primary orthotopic liver transplantation. | 1998 | Transplant. Proc. | pmid:9636564 |
| Tian Ch et al. | B- and T-lymphocyte attenuator/herpes virus entry mediator as early indicators for acute rejection following kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375291 |
| Yao B et al. | The incidence of posttransplantation diabetes mellitus during follow-up in kidney transplant recipients and relationship to Fok1 vitamin D receptor polymorphism. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375298 |
| Fraile P et al. | Non-skin solid tumors as a cause of morbidity and mortality after liver transplantation. | 2009 Jul-Aug | Transplant. Proc. | pmid:19715943 |
| Luk JM et al. | Immunosuppressive effects of Tripterygium wilfordii polysaccharide on LPS-stimulated human monocytes. | 2000 | Transplant. Proc. | pmid:11120045 |
| Abu-Elmagd KM et al. | Monitoring and treatment of intestinal allograft rejection in humans. | 1993 | Transplant. Proc. | pmid:7680150 |
| Mayer AD | Four-year follow-up of the European Tacrolimus Multicenter Renal Study. | 1999 | Transplant. Proc. | pmid:10576038 |
| Farghali H et al. | A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. | 1991 | Transplant. Proc. | pmid:1721284 |
| Jordan ML et al. | Tacrolimus-based immunosuppression in pediatric renal transplantation. | 1999 | Transplant. Proc. | pmid:10576039 |
| Harrison DM et al. | Reduction in hospital stay after liver transplantation. | 1996 | Transplant. Proc. | pmid:8623451 |
| Sathyan S et al. | A case of recurrent immunotactoid glomerulopathy in an allograft treated with rituximab. | 2009 | Transplant. Proc. | pmid:19917422 |
| Kaminska D et al. | Mycophenolate mofetil but not the type of calcineurin inhibitor (cyclosporine vs tacrolimus) influences the intragraft mRNA expression of cytokines in human kidney allograft biopsies by in situ RT-PCR analysis. | 2005 | Transplant. Proc. | pmid:15848526 |
| Schulz T et al. | Tacrolimus/mycophenolate mofetil/steroid-based immunosuppression after pancreas-kidney transplantation with single shot antithymocyte globulin. | 1998 | Transplant. Proc. | pmid:9636623 |
| Ciancio G et al. | Use of intravenous tacrolimus to reverse vascular rejection in kidney and simultaneous kidney-pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636624 |
| Marzoa-Rivas R et al. | Conversion of heart transplant patients from standard to sustained-release tacrolimus requires a dosage increase. | 2010 | Transplant. Proc. | pmid:20970591 |
| Lodewijk L et al. | Effect of liver regeneration on the pharmacokinetics of immunosuppressive drugs. | 2009 Jan-Feb | Transplant. Proc. | pmid:19249561 |
| Takada Y et al. | Energy metabolism of hepatic allografts subjected to prolonged warm ischemia and pharmacologic modulation with FK506 and platelet activating factor antagonist. | 1998 | Transplant. Proc. | pmid:9838621 |
| Nardo B et al. | Pretransplant xenogeneic blood transfusion combined with FK 506 prolongs hamster-to-rat liver xenograft survival. | 1994 | Transplant. Proc. | pmid:7518112 |
| Pan F et al. | FK 506 prolongs survival of liver but not heart mouse-to-rat vascularized xenografts. | 1994 | Transplant. Proc. | pmid:7518113 |
| Wiesner RH et al. | Early cellular rejection treated with high-dose intravenous corticosteroid therapy is associated with a decrease in the incidence of steroid-resistant rejection and graft failure from rejection. | 1993 | Transplant. Proc. | pmid:7682352 |
| Bäckman L et al. | Whole-blood and plasma levels of FK 506 after liver transplantation: results from the US Multicenter Trial. FK506 Multicenter Study Group. | 1995 | Transplant. Proc. | pmid:7533361 |
| Valdivia LA et al. | Complement and target cells belong to the same species after liver xenografting: protection from hyperacute rejection. | 1994 | Transplant. Proc. | pmid:7518123 |
| Frank B et al. | Neurotoxicity of FK 506 in liver transplant recipients. | 1993 | Transplant. Proc. | pmid:7682355 |
| Söderdahl G et al. | FK 506 improves recovery of bile secretion following orthotopic liver transplantation in man. | 1995 | Transplant. Proc. | pmid:7533362 |
| Mor E et al. | Weight gain and lipid profile changes in liver transplant recipients: long-term results of the American FK506 Multicenter Study. | 1995 | Transplant. Proc. | pmid:7533363 |
| Matsuura T et al. | Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. | 1991 | Transplant. Proc. | pmid:1721316 |
| Wynn C et al. | High level of TGF-beta in organ transplantation might be due to rejection rather than calcineurin inhibitor medication. | 2002 | Transplant. Proc. | pmid:12176408 |
| Takeuchi H et al. | Optimal dose and target trough level in cyclosporine and tacrolimus conversion in renal transplantation as evaluated by lymphocyte drug sensitivity and pharmacokinetic parameters. | 2005 | Transplant. Proc. | pmid:15919452 |
| Hohage H et al. | Differential effects of cyclosporine and tacrolimus on mycophenolate pharmacokinetics in patients with impaired kidney function. | 2005 | Transplant. Proc. | pmid:15919453 |
| Ochiai T et al. | Japanese multicenter studies of FK 506 in renal transplantation. Japanese FK 506 Study Group. | 1995 | Transplant. Proc. | pmid:7533419 |
| Takaya S et al. | Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. | 1991 | Transplant. Proc. | pmid:1721348 |
| Sarvary E et al. | De novo Prograf versus de novo Advagraf: are trough level profile curves similar? | Transplant. Proc. | pmid:25131131 | |
| Borda B et al. | Early histopathological changes in new-onset diabetes after kidney transplantation. | Transplant. Proc. | pmid:25131129 | |
| Rabkin JM et al. | Tacrolimus is associated with a lower incidence of cardiovascular complications in liver transplant recipients. | 2002 | Transplant. Proc. | pmid:12176483 |
| Langrehr JM et al. | First results from a prospective randomized trial comparing steroid-free induction therapy with tacrolimus and MMF versus tacrolimus and steroids in patients after liver transplantation for HCV. | 2002 | Transplant. Proc. | pmid:12176487 |
| Oğütmen B et al. | Transforming growth factor-beta1, vascular endothelial growth factor, and bone morphogenic protein-7 expression in tacrolimus-induced nephrotoxicity in rats. | 2006 | Transplant. Proc. | pmid:16549155 |
| Branco KC et al. | The impact of tacrolimus as rescue therapy in children using a double immunosuppressive regimen after heart transplantation. | 2012 | Transplant. Proc. | pmid:23026625 |
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| Nishimoto Y et al. | Real-time monitoring for detecting rejection using strain gauge force transducers in porcine small bowel transplantation. | 2004 | Transplant. Proc. | pmid:15050153 |
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| Prasad SJ et al. | In vitro effects of cyclosporine and FK 506 on the renal cortex. | 1991 | Transplant. Proc. | pmid:1721380 |
| Witzigmann H et al. | Immunosuppression with sirolimus/tacrolimus combination in pancreas transplantation: 1-year results. | 2002 | Transplant. Proc. | pmid:12493472 |
| Kusne S et al. | Early infections in kidney transplant recipients under FK 506. | 1991 | Transplant. Proc. | pmid:1703364 |
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| Terakura M et al. | Effects of peritransplant administration of hematopoietic growth factors on the development of chronic allograft rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083380 |
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