| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatomycoses | D003881 | 17 associated lipids |
| Dermatomyositis | D003882 | 2 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Digestive System Diseases | D004066 | 3 associated lipids |
| Down Syndrome | D004314 | 18 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Niioka T et al. | Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations. | 2017 | Clin. Exp. Nephrol. | pmid:28271256 |
| Gupta AK and Versteeg SG | Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review. | 2017 | Am J Clin Dermatol | pmid:27804089 |
| Suda M et al. | Effectiveness of multi-target therapy in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis with early-stage interstitial lung disease. | 2017 | Scand. J. Rheumatol. | pmid:28649889 |
| Miyake M et al. | Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice. | 2017 | PLoS ONE | pmid:28644884 |
| Chen B et al. | Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in Chinese liver transplant patients. | 2017 | J Clin Pharm Ther | pmid:28833329 |
| Dorr CR et al. | CRISPR/Cas9 Genetic Modification of in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism. | 2017 | Drug Metab. Dispos. | pmid:28533324 |
| Karchin JM et al. | Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly. | 2017 | Sci Rep | pmid:28287617 |
| Mizuno H et al. | Extranodal NK/T cell lymphoma in a living donor liver transplant recipient. | 2017 | Ann. Hematol. | pmid:28280996 |
| Zhang HJ et al. | Tacrolimus population pharmacokinetics according to CYP3A5 genotype and clinical factors in Chinese adult kidney transplant recipients. | 2017 | J Clin Pharm Ther | pmid:28401703 |
| Mertens JS et al. | Morphea and Eosinophilic Fasciitis: An Update. | 2017 | Am J Clin Dermatol | pmid:28303481 |
| Dhakal P et al. | Eculizumab in Transplant-Associated Thrombotic Microangiopathy. | 2017 | Clin. Appl. Thromb. Hemost. | pmid:26259912 |
| Albaghdadi AJ et al. | Tacrolimus in the prevention of adverse pregnancy outcomes and diabetes-associated embryopathies in obese and diabetic mice. | 2017 | J Transl Med | pmid:28193233 |
| Unadkat JV et al. | Single Implantable FK506 Disk Prevents Rejection in Vascularized Composite Allotransplantation. | 2017 | Plast. Reconstr. Surg. | pmid:28121868 |
| Chapman WC et al. | Effect of Early Everolimus-Facilitated Reduction of Tacrolimus on Efficacy and Renal Function in De Novo Liver Transplant Recipients: 24-Month Results for the North American Subpopulation. | 2017 | Transplantation | pmid:28121741 |
| Riva N et al. | Adequate exposure to tacrolimus with sublingual administration in pediatric liver transplant patients. | 2017 | Int J Clin Pharmacol Ther | pmid:28079516 |
| Ishida R et al. | The Tissue-Reconstructing Ability of Colon CSCs Is Enhanced by FK506 and Suppressed by GSK3 Inhibition. | 2017 | Mol. Cancer Res. | pmid:28710230 |
| Mussin N et al. | Sirolimus and Metformin Synergistically Inhibits Colon Cancer In Vitro and In Vivo. | 2017 | J. Korean Med. Sci. | pmid:28776332 |
| Barau C et al. | Pharmacokinetics of Mycophenolic Acid and Dose Optimization in Children After Intestinal Transplantation. | 2017 | Ther Drug Monit | pmid:27898598 |
| Nanmoku K et al. | Effective and Safe Reduction of Conventional Immunosuppressants Using Everolimus in Maintenance Kidney Transplant Recipients. | 2017 | Transplant. Proc. | pmid:28923615 |
| Sakassegawa-Naves FE et al. | Tacrolimus Ointment for Refractory Posterior Blepharitis. | 2017 | Curr. Eye Res. | pmid:28922018 |