tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oh CK et al. | Safety and efficacy of conversion from twice-daily tacrolimus to once-daily tacrolimus one month after transplantation: randomized controlled trial in adult renal transplantation. | 2014 | Yonsei Med. J. | pmid:25048494 |
| Schwarz A | [Drug-induced kidney damage]. | 1996 | Z Arztl Fortbild (Jena) | pmid:8779233 |
| Ocran KW et al. | Tacrolimus toxicity due to drug interaction with mibefradil in a patient after liver transplantation. | 1999 | Z Gastroenterol | pmid:10549098 |
| Müller MK et al. | [Pathophysiologic concepts and protective possibilities in experimental pancreatic lesions]. | 1993 | Z Gastroenterol | pmid:7504856 |
| Petrides AS | [Do immunosuppressive agents really impair glucose tolerance in liver transplant patients?]. | 1995 | Z Gastroenterol | pmid:7571761 |
| Arnold JC and Theilmann L | [Comparison between tacrolimus (FK 506) and cyclosporin in immunosuppressive therapy after liver transplantation]. | 1995 | Z Gastroenterol | pmid:7502559 |
| Buechter M et al. | Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis. | 2014 | Z Gastroenterol | pmid:24905108 |
| Kanzler S et al. | Complete reversal of FK 506 induced diabetes in a liver transplant recipient by change of immunosuppression to cyclosporine A. | 1996 | Z Gastroenterol | pmid:8659188 |
| Grube E et al. | Drug eluting stents: initial experiences. | 2002 | Z Kardiol | pmid:12641014 |
| Scheller B et al. | Comparative study of tacrolimus and paclitaxel stent coating in the porcine coronary model. | 2005 | Z Kardiol | pmid:15997345 |
| König A et al. | Intravascular ultrasound for assessment of coronary allograft vasculopathy. | 2000 | Z Kardiol | pmid:11151792 |
| Weiner SM | [Combination of tacrolimus and MMF for treatment of proliferative lupus nephritis]. | 2016 | Z Rheumatol | pmid:27259912 |
| Lütkes P et al. | [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. | 1999 | Zentralbl Chir | pmid:10209841 |
| David M et al. | [Changes in cervix cytology in women with liver transplants treated with immunosuppressive therapy]. | 1993 | Zentralbl Gynakol | pmid:7692689 |
| Liu Y and Zheng M | [Suppression of Tacrolimus on the expression of MMP-9 in rhHGF-stimulated ECV304 cell line]. | 2004 | Zhejiang Da Xue Xue Bao Yi Xue Ban | pmid:15586415 |
| Li Y et al. | [Effects of tacrolimus and cyclosporine on albumin secretion in cultured human hepatocyte]. | 2006 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:16859130 |
| Peng LK et al. | [Slowing progression of chronic allograft nephropathy by conversion from cyclosporin A to tacrolimus]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17344588 |
| Li D et al. | [Effect of genetic polymorphism on disposition of calcineurin inhibitors in solid organ transplantation]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:20871172 |
| Chiu MC | Management strategy for idiopathic nehprotic syndrome in children. | 2008 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:18245896 |
| Sun Y et al. | [Total glucosides of peony as adjuvant therapy for prevention of cardiac allograft rejection in rats]. | 2007 | Zhong Xi Yi Jie He Xue Bao | pmid:17854565 |