tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dysgammaglobulinemia D004406 3 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Down Syndrome D004314 18 associated lipids
Digestive System Diseases D004066 3 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatomyositis D003882 2 associated lipids
Dermatomycoses D003881 17 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Dental Pulp Calcification D003784 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Dehydration D003681 11 associated lipids
Deglutition Disorders D003680 2 associated lipids
Hearing Loss, Sudden D003639 1 associated lipids
Phyllodes Tumor D003557 1 associated lipids
Cystitis D003556 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cutis Laxa D003483 1 associated lipids
Cryptococcosis D003453 3 associated lipids
Crohn Disease D003424 12 associated lipids
Crigler-Najjar Syndrome D003414 1 associated lipids
Cough D003371 19 associated lipids
Corneal Diseases D003316 13 associated lipids
Connective Tissue Diseases D003240 2 associated lipids
Confusion D003221 4 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Collagen Diseases D003095 2 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colitis D003092 69 associated lipids
Coccidioidomycosis D003047 2 associated lipids
Cicatrix D002921 9 associated lipids
Chronic Disease D002908 7 associated lipids
Hemophilia B D002836 3 associated lipids
Choline Deficiency D002796 16 associated lipids
Cholestasis D002779 23 associated lipids
Cholelithiasis D002769 16 associated lipids
Cheilitis D002613 2 associated lipids
Uterine Cervical Dysplasia D002578 2 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Xie ZQ et al. [Antipruritic mechanisms of pimecrolimus cream for facial dermatitis in adult women patients]. 2009 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:19317053
Wen J et al. [Regulatory effects of cyclosporin A and tacrolimus on the immunological gene expressions in renal transplant recipients]. 2012 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:23286399
Xie ZQ and Lan YZ Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. 2012 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:22954121
Chen GF et al. [Peripheral nerve regeneration under immunosuppression]. 2002 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:11944523
Xiong G et al. [Effects of immunosuppressants on proliferation of pheochromocytoma 12 and L929 cells]. 2007 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:17694665
Kang H et al. [Combined immunosuppression of FK506 and RS-61443 in rat limb allotransplantation]. 2003 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:12822367
Yu HQ et al. [Study of tacrolimus intranasal treatment for allergic asthma in mice]. 2012 Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi pmid:23484272
Li Q et al. [Experimental study of electrophysiologic effects of regenerative nerve fibres affected by control releasing FK506]. 2010 Zhongguo Gu Shang pmid:21254678
Li Y et al. [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. 2017 Zhongguo Fei Ai Za Zhi pmid:28738959
Zhou Y et al. [Effect of tacrolimus on growth-associated protein-43 expression in the hippocampus of neonatal rats with hypoxic-ischemic brain damage]. 2009 Zhongguo Dang Dai Er Ke Za Zhi pmid:19149927
Huang WY [Clinical application and side effects of immunosuppressant]. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17448303
Sun Y et al. [Total glucosides of peony as adjuvant therapy for prevention of cardiac allograft rejection in rats]. 2007 Zhong Xi Yi Jie He Xue Bao pmid:17854565
Li Y et al. [Effects of tacrolimus and cyclosporine on albumin secretion in cultured human hepatocyte]. 2006 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16859130
Peng LK et al. [Slowing progression of chronic allograft nephropathy by conversion from cyclosporin A to tacrolimus]. 2007 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:17344588
Li D et al. [Effect of genetic polymorphism on disposition of calcineurin inhibitors in solid organ transplantation]. 2010 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:20871172
Chiu MC Management strategy for idiopathic nehprotic syndrome in children. 2008 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:18245896
Liu Y and Zheng M [Suppression of Tacrolimus on the expression of MMP-9 in rhHGF-stimulated ECV304 cell line]. 2004 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:15586415
David M et al. [Changes in cervix cytology in women with liver transplants treated with immunosuppressive therapy]. 1993 Zentralbl Gynakol pmid:7692689
Lütkes P et al. [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. 1999 Zentralbl Chir pmid:10209841
Weiner SM [Combination of tacrolimus and MMF for treatment of proliferative lupus nephritis]. 2016 Z Rheumatol pmid:27259912