tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dysgammaglobulinemia D004406 3 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Down Syndrome D004314 18 associated lipids
Digestive System Diseases D004066 3 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatomyositis D003882 2 associated lipids
Dermatomycoses D003881 17 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Dental Pulp Calcification D003784 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Dehydration D003681 11 associated lipids
Deglutition Disorders D003680 2 associated lipids
Hearing Loss, Sudden D003639 1 associated lipids
Phyllodes Tumor D003557 1 associated lipids
Cystitis D003556 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cutis Laxa D003483 1 associated lipids
Cryptococcosis D003453 3 associated lipids
Crohn Disease D003424 12 associated lipids
Crigler-Najjar Syndrome D003414 1 associated lipids
Cough D003371 19 associated lipids
Corneal Diseases D003316 13 associated lipids
Connective Tissue Diseases D003240 2 associated lipids
Confusion D003221 4 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Collagen Diseases D003095 2 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colitis D003092 69 associated lipids
Coccidioidomycosis D003047 2 associated lipids
Cicatrix D002921 9 associated lipids
Chronic Disease D002908 7 associated lipids
Hemophilia B D002836 3 associated lipids
Choline Deficiency D002796 16 associated lipids
Cholestasis D002779 23 associated lipids
Cholelithiasis D002769 16 associated lipids
Cheilitis D002613 2 associated lipids
Uterine Cervical Dysplasia D002578 2 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Sugimoto K et al. Assessment of Long-Term Efficacy and Safety of Adalimumab in Patients with Ulcerative Colitis: Results from a 6-Year Real-World Clinical Practice. 2019 Dig Dis pmid:30205400
Liu L et al. New insights of subfertility among transplanted women: Immunosuppressive drug FK506 leads to calcium leak and oocyte activation before fertilization. 2018 J. Cell. Biochem. pmid:29131377
Pham TT et al. Tissue adhesive FK506-loaded polymeric nanoparticles for multi-layered nano-shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model. 2018 Biomaterials pmid:29128846
Bond MMK et al. Cyclosporine Versus Tacrolimus: Which Calcineurin Inhibitor Has Influence on Cytomegalovirus Infection in Cardiac Transplantation? 2018 Transplant. Proc. pmid:29661443
Lee WS et al. Tacrolimus regulates endoplasmic reticulum stress-mediated osteoclastogenesis and inflammation: In vitro and collagen-induced arthritis mouse model. 2018 Cell Biol. Int. pmid:28833755
Quintero J et al. Conversion from twice-daily to once-daily tacrolimus formulation in pediatric liver transplant recipients - a long-term prospective study. 2018 Transpl. Int. pmid:28833714
Jiang JW et al. Optimal immunosuppressor induces stable gut microbiota after liver transplantation. 2018 World J. Gastroenterol. pmid:30228781
Gu B et al. Exploration of Fecal Microbiota Transplantation in the Treatment of Refractory Diarrhea After Renal Transplantation. 2018 Transplant. Proc. pmid:29880353
Lee H et al. Thymoglobulin Versus Basiliximab Induction Therapy in Low-Risk Kidney Transplant Recipients: A Single-Center Experience. 2018 Transplant. Proc. pmid:29880348
Marquet P et al. Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online. 2018 Ther Drug Monit pmid:29505493
Chen J et al. Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. 2018 J. Biol. Chem. pmid:29330302
Ichinose K et al. The efficacy of adjunct tacrolimus treatment in pregnancy outcomes in patients with systemic lupus erythematosus. 2018 Lupus pmid:29665758
Ishikawa S et al. Management of Juvenile Idiopathic Arthritis in ABO-incompatible Kidney Transplantation: A Case Report. 2018 Transplant. Proc. pmid:29661455
Mei S et al. Simultaneous determination of cyclosporine and tacrolimus in human whole blood by ultra-high performance liquid chromatography tandem mass spectrometry and comparison with a chemiluminescence microparticle immunoassay. 2018 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:29704799
Stanton BZ et al. Chemically induced proximity in biology and medicine. 2018 Science pmid:29590011
Okada K et al. EBV-positive PEL-like lymphoma that developed in the course of antisynthetase syndrome treated with tacrolimus. 2018 Int. J. Hematol. pmid:29516290
Sano H et al. T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia. 2018 Int. J. Hematol. pmid:29508228
Takeuchi T et al. Post-marketing surveillance study of the long-term use of mizoribine for the treatment of lupus nephritis: 2-Year results. 2018 Mod Rheumatol pmid:28722500
Oetting WS et al. Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients. 2018 Pharmacogenomics pmid:29318894
Rayar M et al. High Intrapatient Variability of Tacrolimus Exposure in the Early Period After Liver Transplantation Is Associated With Poorer Outcomes. 2018 Transplantation pmid:29315140