Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Segura S et al. | Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. | 2005 | Acta Derm. Venereol. | pmid:16396803 |
de la Rosa Carrillo D and Christensen OB | Treatment of chronic discoid lupus erythematosus with topical tacrolimus. | 2004 | Acta Derm. Venereol. | pmid:15202845 |
Halvorsen JA and Aasebø W | Oral tacrolimus treatment of pruritus in prurigo nodularis. | 2015 | Acta Derm. Venereol. | pmid:25804254 |
Masuda K et al. | Increased levels of serum interleukin-16 in adult type atopic dermatitis. | 2003 | Acta Derm. Venereol. | pmid:12926794 |
Yamamoto T and Nishioka K | Deep dermatophytosis during topical tacrolimus therapy for psoriasis. | 2003 | Acta Derm. Venereol. | pmid:12926803 |
Sand C | Topical tacrolimus ointment may induce skin tags in treated patients. | 2003 | Acta Derm. Venereol. | pmid:12926817 |
Park SW et al. | Topical tacrolimus (FK506): treatment failure in four cases of alopecia universalis. | 2002 | Acta Derm. Venereol. | pmid:12430746 |
Mrowietz U et al. | An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. | 2003 | Acta Derm. Venereol. | pmid:14609102 |
Yamamoto T and Nishioka K | Topical tacrolimus is effective for facial lesions of psoriasis. | 2000 Nov-Dec | Acta Derm. Venereol. | pmid:11243645 |
Lee HY et al. | Oral mucous membrane pemphigoid: complete response to topical tacrolimus. | 2011 | Acta Derm. Venereol. | pmid:21597668 |