Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Patel CG et al. | Mycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus. | 2013 | Xenobiotica | pmid:22934787 |
Niioka T et al. | Effects of CYP3A5 polymorphism and the tacrolimus 12 h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis. | 2015 | Xenobiotica | pmid:26189776 |
Gupta AS et al. | Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant. | 2018 | Wounds | pmid:29481333 |
Kiyama T et al. | Tacrolimus enhances colon anastomotic healing in rats. | 2002 Sep-Oct | Wound Repair Regen | pmid:12406167 |
Yang J et al. | Zinc finger protein A20 protects rats against chronic liver allograft dysfunction. | 2012 | World J. Gastroenterol. | pmid:22826618 |
Zhou J et al. | Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. | 2006 | World J. Gastroenterol. | pmid:16718799 |
Meier J and Sturm A | Current treatment of ulcerative colitis. | 2011 | World J. Gastroenterol. | pmid:21912469 |
Higashi H et al. | First successful perinatal management of pregnancy after ABO-incompatible liver transplantation. | 2017 | World J. Gastroenterol. | pmid:28210092 |
Indriolo A and Ravelli P | Clinical management of inflammatory bowel disease in the organ recipient. | 2014 | World J. Gastroenterol. | pmid:24707135 |
Shen T et al. | Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. | 2015 | World J. Gastroenterol. | pmid:26034381 |