tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

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Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Nephritis, Hereditary D009394 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Collagen Diseases D003095 2 associated lipids
Pruritus Vulvae D011539 1 associated lipids
Phyllodes Tumor D003557 1 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Anemia, Refractory D000753 3 associated lipids
Pulmonary Veno-Occlusive Disease D011668 1 associated lipids
Tongue Diseases D014060 2 associated lipids
Beckwith-Wiedemann Syndrome D001506 1 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Rheumatoid Nodule D012218 1 associated lipids
Granuloma Annulare D016460 1 associated lipids
Hypoplastic Left Heart Syndrome D018636 1 associated lipids
Incontinentia Pigmenti D007184 2 associated lipids
Discitis D015299 2 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Akinetic Mutism D000405 1 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Histiocytosis D015614 2 associated lipids
Mastocytosis, Cutaneous D034701 1 associated lipids
Mediastinal Emphysema D008478 1 associated lipids
Invasive Pulmonary Aspergillosis D055744 1 associated lipids
Netherton Syndrome D056770 1 associated lipids
Coccidioidomycosis D003047 2 associated lipids
Meningitis, Fungal D016921 1 associated lipids
Panniculitis, Lupus Erythematosus D015435 1 associated lipids
Lymphohistiocytosis, Hemophagocytic D051359 1 associated lipids
Rupture D012421 2 associated lipids
Lichen Nitidus D017513 1 associated lipids
Eye Infections, Fungal D015821 2 associated lipids
Hypoalbuminemia D034141 1 associated lipids
Porokeratosis D017499 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Scleritis D015423 3 associated lipids
Multiple Endocrine Neoplasia Type 2a D018813 1 associated lipids
Intertrigo D007402 1 associated lipids
Impetigo D007169 3 associated lipids
Nocturnal Myoclonus Syndrome D020189 1 associated lipids
Pterygium D011625 3 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Mucinoses D017520 2 associated lipids
Carcinoma, Merkel Cell D015266 2 associated lipids
Nocturia D053158 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Malacoplakia D008287 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Ohara M et al. Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy. 2018 Intern. Med. pmid:29269644
Hasegawa M et al. Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus. 2018 J. Dermatol. pmid:29265410
Li YM et al. Impact of immunosuppressive drugs on circulating Tfh cells in kidney transplant recipients: A pilot study. 2018 Transpl. Immunol. pmid:28974433
Shuker N et al. Intrapatient Variability in Tacrolimus Exposure Does Not Predict The Development of Cardiac Allograft Vasculopathy After Heart Transplant. 2018 Exp Clin Transplant pmid:28969528
Huang F et al. Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study. 2018 Basic Clin. Pharmacol. Toxicol. pmid:29427400
Shank BR et al. Interdisciplinary implementation of tacrolimus intravenous standard concentration in hematopoietic stem cell transplantation recipients. 2018 J Oncol Pharm Pract pmid:28554241
González-Vílchez F et al. Efficacy and Safety of de Novo and Early Use of Extended-release Tacrolimus in Heart Transplantation. 2018 Rev Esp Cardiol (Engl Ed) pmid:28545984
Fonseca ACRG et al. Calcineurin is an important factor involved in glucose uptake in human adipocytes. 2018 Mol. Cell. Biochem. pmid:29380240
Vandenbussche C et al. Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. 2018 Arch. Toxicol. pmid:29362864
Tillmann FP et al. Impact of low-dose steroids on HbA1c levels and development of pre-diabetes and NODAT in non-diabetic renal transplant recipients on long-term follow-up. 2018 Int Urol Nephrol pmid:29197933
Li P et al. Risk factors for BK virus infection in living-donor renal transplant recipients: a single-center study from China. 2018 Ren Fail pmid:30052479
Thoms S et al. Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. 2018 Toxicol In Vitro pmid:30048735
Cai W et al. Limited Sampling Strategy for Estimating Mycophenolic Acid Exposure on Day 7 Post-Transplant for Two Mycophenolate Mofetil Formulations Derived From 20 Chinese Renal Transplant Recipients. 2018 Transplant. Proc. pmid:29735215
Chung YW et al. Tacrolimus-Induced Apoptosis is Mediated by Endoplasmic Reticulum-derived Calcium-dependent Caspases-3,-12 in Jurkat Cells. 2018 Transplant. Proc. pmid:29731088
Lee KH et al. Distribution of Anti-ABO Immunoglobulin G Subclass and C1q Antibody in ABO-incompatible Kidney Transplantation. 2018 Transplant. Proc. pmid:29731066
Youssef A et al. Angiolymphoid hyperplasia with eosinophilia: a case report. 2018 J Med Case Rep pmid:29606120
Hu R et al. CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. 2018 Basic Clin. Pharmacol. Toxicol. pmid:29603629
Schuh MJ and Massoglia G Pharmacist Impact on Tacrolimus Serum Concentrations in Liver Transplant Patients. 2018 Consult Pharm pmid:29789048
Konma J et al. Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study. 2018 Mod Rheumatol pmid:29442534
Hashemian MN et al. Topical Tacrolimus as Adjuvant Therapy to Corticosteroids in Acute Endothelial Graft Rejection After Penetrating Keratoplasty: A Randomized Controlled Trial. 2018 Cornea pmid:29215395