Doi R et al. |
Biochemical characterization of the effects of FK506 on signal transduction in exocytotic function of rat pancreatic acini. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7679738
|
Cavaillé-Coll M and Mielach FA |
Choice of cyclophosphamide dose in baboon-to-human liver transplantation. |
1993 |
Lancet |
pmid:7679768
|
Kobayashi M et al. |
HLA-DR matching effect in orthotopic liver transplantation under FK 506. |
1993 |
Transplant. Proc. |
pmid:7679812
|
Stock PG et al. |
Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity. |
1993 |
Transplant. Proc. |
pmid:7679838
|
Tabasco-Minguillan J et al. |
Long-term insulin requirement after liver transplantation with FK 506 in American veterans. |
1993 |
Transplant. Proc. |
pmid:7679839
|
Klintmalm GB et al. |
Use of Prograf (FK 506) as rescue therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group. |
1993 |
Transplant. Proc. |
pmid:7679840
|
Gunji Y et al. |
Pathologic characteristics of vasculitis in renal transplant recipient dogs receiving immunosuppressive agents, FK 506, rapamycin, or RS-61443. |
1993 |
Transplant. Proc. |
pmid:7679841
|
Gregory CR et al. |
Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo. |
1993 |
Transplant. Proc. |
pmid:7679842
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors. |
1993 |
Transplant. Proc. |
pmid:7679843
|
Inoue T et al. |
Isolation of mitochondrial cyclophilin from bovine heart. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7679902
|
Stephens J et al. |
Effects of orthotopic liver transplantation and immunosuppression on inflammatory bowel disease in primary sclerosing cholangitis patients. |
1993 |
Transplant. Proc. |
pmid:7680144
|
Bonet H et al. |
Survival of patients transplanted with alcoholic hepatitis plus cirrhosis as compared with those with cirrhosis alone. |
1993 |
Transplant. Proc. |
pmid:7680145
|
Jayaraman T and Marks AR |
Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. |
1993 |
J. Biol. Chem. |
pmid:7503980
|
D'Ambrosio R et al. |
Validation and quality assurance program for monitoring tacrolimus (FK 506) concentrations in plasma and whole blood. |
1993 |
Ther Drug Monit |
pmid:7504339
|
Reese JC et al. |
The effect of FK506 on canine bile flow. |
1993 |
Transplantation |
pmid:7504342
|
Woodle ES et al. |
FK506--reversal of humorally mediated cardiac allograft rejection in the presence of preformed anti-class I antibody. |
1993 |
Transplantation |
pmid:7504346
|
Valdivia LA et al. |
Successful hamster-to-rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin. |
1993 |
Transplantation |
pmid:7681230
|
Jindal RM et al. |
Effect of deoxyspergualin on the endocrine function of the rat pancreas. |
1993 |
Transplantation |
pmid:7504347
|
Fujimura A et al. |
Chronopharmacokinetic study of a new immunosuppressive agent, FK 506, in mice. |
1993 |
Jpn. J. Pharmacol. |
pmid:7681489
|
Kodama M et al. |
FK506 therapy of experimental autoimmune myocarditis after onset of the disease. |
1993 |
Am. Heart J. |
pmid:7504393
|
Nishinaka Y et al. |
Protective effect of FK506 on ischemia/reperfusion-induced myocardial damage in canine heart. |
1993 |
J. Cardiovasc. Pharmacol. |
pmid:7681507
|
Yem AW et al. |
An active FK506-binding domain of 17,000 daltons is isolated following limited proteolysis of chicken thymus hsp56. |
1993 |
Biochemistry |
pmid:7504525
|
Luan S et al. |
Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7681590
|
Manev H et al. |
Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate. |
1993 |
Brain Res. |
pmid:7504570
|
Doi R et al. |
Structural and functional changes of exocrine pancreas induced by FK506 in rats. |
1993 |
Gastroenterology |
pmid:7681795
|
Rotonda J et al. |
Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis. |
1993 |
J. Biol. Chem. |
pmid:7681823
|
Xu RX et al. |
1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin. |
1993 |
Biopolymers |
pmid:7682113
|
Tanaka N et al. |
Regulation of liver regeneration by interleukin-2 and its inhibitors: cyclosporine A and FK 506. |
1993 |
Int. J. Immunopharmacol. |
pmid:7682200
|
Peters DH et al. |
Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. |
1993 |
Drugs |
pmid:7506654
|
Mühl H et al. |
Cyclosporin derivatives inhibit interleukin 1 beta induction of nitric oxide synthase in renal mesangial cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7506668
|
Simek SL et al. |
Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. |
1993 |
Genomics |
pmid:7507077
|
Lhoëst G et al. |
Isolation and identification by FAB mass spectrometry and NMR spectroscopy of a demethylated metabolite of FK506 from erythromycin-induced rabbit liver microsomes. |
1993 |
Pharm Acta Helv |
pmid:7692454
|
Izumi S and Okuhara M |
[FK506 and kifunensine, new immunomodulators of microbial origin]. |
1993 |
Tanpakushitsu Kakusan Koso |
pmid:7692469
|
Wakugami T et al. |
Effect of FK506 on the development of diabetes in BB rats in comparison with that of cyclosporin. |
1993 |
Tohoku J. Exp. Med. |
pmid:7692621
|
Quesniaux VF |
Immunosuppressants: tools to investigate the physiological role of cytokines. |
1993 |
Bioessays |
pmid:7507316
|
Hill CC et al. |
Penile prosthesis surgery in the immunosuppressed patient. |
1993 |
Transplantation |
pmid:7692633
|
Roberts JP et al. |
Reversal of chronic rejection after treatment failure with FK506 and RS61443. |
1993 |
Transplantation |
pmid:7692634
|
Fernandes JB et al. |
Comparative investigation of the effects of the immunosuppressants cyclosporine A, cyclosporine G, and FK-506 on platelet activation. |
1993 |
Cell. Mol. Biol. Res. |
pmid:7507391
|
Storb R et al. |
FK-506 and methotrexate prevent graft-versus-host disease in dogs given 9.2 Gy total body irradiation and marrow grafts from unrelated dog leukocyte antigen-nonidentical donors. |
1993 |
Transplantation |
pmid:7692635
|
McDiarmid SV et al. |
A comparison of renal function in cyclosporine- and FK-506-treated patients after primary orthotopic liver transplantation. |
1993 |
Transplantation |
pmid:7692636
|
Tabasco-Minguillan J et al. |
Insulin requirements after liver transplantation and FK-506 immunosuppression. |
1993 |
Transplantation |
pmid:7692637
|
Wang SC et al. |
A dual mechanism of immunosuppression by FK-506. Differential suppression of IL-4 and IL-10 levels in T helper 2 cells. |
1993 |
Transplantation |
pmid:7692640
|
Sato M et al. |
FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. |
1993 |
Acta Endocrinol. |
pmid:7509103
|
Clipstone NA and Crabtree GR |
Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509131
|
Takahara S |
Efficacy of FK506 in renal transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509132
|
Thomson AW et al. |
Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509133
|
Lemster B et al. |
FK 506 inhibits cytokine gene and adhesion molecule expression in psoriatic skin lesions. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509134
|
Blaehr H et al. |
Acute effects of FK506 and cyclosporine A on cultured human proximal tubular cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7683267
|
Tamura K et al. |
Inhibitory effect of FK 506 on autoimmune thyroid disease in the PVG rat. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509135
|
Kadmon M et al. |
Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. |
1993 |
Gastroenterology |
pmid:7683296
|
Denesyuk AI et al. |
Structural similarity of the binding sites of cyclophilin A-cyclosporin A and FKBP-FK506 systems. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7683466
|
Waschulewski IH et al. |
Effects of the immunosuppressants cyclosporin A and FK 506 on exocytosis in the rat exocrine pancreas in vitro. |
1993 |
Br. J. Pharmacol. |
pmid:7683567
|
Ohtake M et al. |
Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506. |
1993 |
Gastroenterol. Jpn. |
pmid:7683616
|
Ohnishi H et al. |
Natural killer cell may impair liver regeneration in fulminant hepatic failure. |
1993 |
Gastroenterol. Jpn. |
pmid:7683619
|
Natazuka T et al. |
FK506 and cyclosporin a regulate proliferation and proto-oncogene expression in HTLV-1-associated myelopathy/tropical-spastic-paraparesis-derived T cells. |
1993 |
Int. J. Cancer |
pmid:7683633
|
Mukai H et al. |
FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms. |
1993 |
J. Biochem. |
pmid:7683641
|
Moutabarrik A et al. |
Effect of FK 506 and cyclosporine on the expression of IL-6 and its receptor on stimulated monocytes. |
1993 |
Transplant. Proc. |
pmid:7685949
|
Takaya S et al. |
Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506. |
1993 |
Transplant. Proc. |
pmid:7685953
|
Murphy MP and Morris RE |
Brequinar sodium effectively and potently suppresses allograft rejection in a heterotopic mouse heart transplant model. |
1993 |
Transplant. Proc. |
pmid:7685955
|
Li W and Handschumacher RE |
Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin. |
1993 |
J. Biol. Chem. |
pmid:7686148
|
Hibbins M et al. |
Inhibition of PHA induced mononuclear cell proliferation by FK506 in combination with cyclosporine, methylprednisolone, 6-mercaptopurine and mycophenolic acid. |
1993 |
Transpl. Immunol. |
pmid:7521736
|
Wong PY et al. |
Recurrence of primary biliary cirrhosis after liver transplantation following FK506-based immunosuppression. |
1993 |
J. Hepatol. |
pmid:7686192
|
Sakr MF et al. |
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion. |
1993 |
J. Hepatol. |
pmid:7686193
|
Calne RY et al. |
Intestinal transplant for recurring mesenteric desmoid tumour. |
1993 |
Lancet |
pmid:7686241
|
Langer A et al. |
Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection. Marked stimulation of IgM++bright/IgD+dull splenic B cells. |
1993 |
Am. J. Pathol. |
pmid:7686346
|
Morkawa K et al. |
Immunosuppressive property of bromocriptine on human B lymphocyte function in vitro. |
1993 |
Clin. Exp. Immunol. |
pmid:7688676
|
Yamaoka K et al. |
Cyclosporin A and FK506 block the negative signaling mediated by surface IgM cross-linking in normal human mature B cells. |
1993 |
Immunol. Lett. |
pmid:7688712
|
Smith DF et al. |
Two FKBP-related proteins are associated with progesterone receptor complexes. |
1993 |
J. Biol. Chem. |
pmid:7688746
|
Jacobs JC et al. |
Pyoderma gangrenosum in infancy. |
1993 |
J. Am. Acad. Dermatol. |
pmid:7688775
|
Garrity GM et al. |
Genetic relationships among actinomycetes that produce the immunosuppressant macrolides FK506, FK520/FK523 and rapamycin. |
1993 |
J. Ind. Microbiol. |
pmid:7688970
|
Hoof T et al. |
Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin. |
1993 |
Eur. J. Pharmacol. |
pmid:7689059
|
Jin YJ and Burakoff SJ |
The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7689229
|
Taylor-Fishwick DA et al. |
Evidence that rapamycin has differential effects of IL-4 function. Multiple IL-4 signaling pathways and implications for in vivo use. |
1993 |
Transplantation |
pmid:7689258
|
Shaefer MS et al. |
Falsely elevated FK-506 levels caused by sampling through central venous catheters. |
1993 |
Transplantation |
pmid:7689264
|
Reem GH et al. |
FK-506 inhibits the IL-2-independent induction of the activation antigen CD 69. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689811
|
Mollison KW et al. |
Comparison of FK-506, rapamycin, ascomycin, and cyclosporine in mouse models of host-versus-graft disease and heterotopic heart transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689812
|
Tai PK et al. |
P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors. |
1993 |
Biochemistry |
pmid:7689858
|
Lieberman R |
FK506, artificial intelligence and pharmacoeconomics. |
1993 |
J Clin Pharmacol |
pmid:7690045
|
McMichael J et al. |
An intelligent and cost-effective computer dosing system for individualizing FK506 therapy in transplantation and autoimmune disorders. |
1993 |
J Clin Pharmacol |
pmid:7690046
|
Jain AB et al. |
Pharmacokinetics of FK506 in liver transplant recipients after continuous intravenous infusion. |
1993 |
J Clin Pharmacol |
pmid:7690047
|
Cheng JW et al. |
15N NMR relaxation studies of the FK506 binding protein: backbone dynamics of the uncomplexed receptor. |
1993 |
Biochemistry |
pmid:7690248
|
Cetinkale O et al. |
The use of FK506 and skin allografting for the treatment of severe burns in an animal model. |
1993 |
Br J Plast Surg |
pmid:7690295
|
McCaffrey PG et al. |
NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs. |
1993 |
J. Biol. Chem. |
pmid:7679116
|
Armitage JM et al. |
Pediatric lung transplantation. The years 1985 to 1992 and the clinical trial of FK 506. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7679172
|
Ito K and Komatsu Y |
[Drug induced hemolytic uremic syndrome]. |
1993 |
Nippon Rinsho |
pmid:7679450
|
Langrehr JM et al. |
Clinical course, morphology, and treatment of chronically rejecting small bowel allografts. |
1993 |
Transplantation |
pmid:7679526
|
Uemoto S et al. |
Experience with FK506 in living-related liver transplantation. |
1993 |
Transplantation |
pmid:7679528
|
Talento A et al. |
A single administration of LFA-1 antibody confers prolonged allograft survival. |
1993 |
Transplantation |
pmid:7679531
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Metcalfe S et al. |
FK506 and rapamycin: differential sensitivity of human, baboon, cynomolgus monkey, dog and pig lymphocytes. |
1992 |
Transpl. Int. |
pmid:14621863
|
Meingassner JG and Stütz A |
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases? |
1992 |
J. Invest. Dermatol. |
pmid:1375617
|
Clipstone NA and Crabtree GR |
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. |
1992 |
Nature |
pmid:1377362
|
Cai X et al. |
Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. |
1992 |
Transplant. Proc. |
pmid:1379759
|
Xu RX et al. |
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants. |
1992 |
FEBS Lett. |
pmid:1377648
|