tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Sinusitis D012852 9 associated lipids
Cicatrix D002921 9 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Leukocytosis D007964 9 associated lipids
Opportunistic Infections D009894 8 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Candidiasis, Vulvovaginal D002181 8 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
Thyroid Diseases D013959 8 associated lipids
Fistula D005402 8 associated lipids
Renal Insufficiency D051437 8 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Folliculitis D005499 7 associated lipids
Granuloma, Giant Cell D006101 7 associated lipids
Facial Dermatoses D005148 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Randhawa PS et al. Clinical significance of renal biopsies showing concurrent acute rejection and tacrolimus-associated tubular vacuolization. 1999 Transplantation pmid:9921801
Yoshida A et al. Studies of repeated administration of FK-506 on myocardial metabolism in rats. 1998 J Toxicol Sci pmid:9922943
Wingard JR et al. Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. 1998 Biol. Blood Marrow Transplant. pmid:9923414
Cai Q et al. Reduction of infarct size in isolated rat heart by CsA and FK506: possible role of phosphatase inhibition. 1998 Cardiovasc Drugs Ther pmid:9926283
Honoré P et al. [Liver transplantation: experiences and results of a program at the University of Liege]. 1998 Rev Med Liege pmid:9927867
Al-Nasser IA In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506. 1998 Toxicology pmid:9928632
Takeda Y et al. Mechanisms of FK 506-induced hypertension in the rat. 1999 Hypertension pmid:9931093
Hebebrand D et al. [Genetic methods in experimental xenogenic nerve transplantation]. 1998 Langenbecks Arch Chir Suppl Kongressbd pmid:9931858
Nakahama H et al. Effect of a novel immunosuppressant, FK 506, on autoimmune glomerulonephritis in Brown Norway rats. 1999 Nephron pmid:9933758
Hebert MF et al. Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers. 1999 J Clin Pharmacol pmid:9987705
Mrowietz U et al. The novel ascomycin derivative SDZ ASM 981 is effective for psoriasis when used topically under occlusion. 1998 Br. J. Dermatol. pmid:9990361