Thomson AW et al. |
FK 506, cardiac transplantation, and graft-vessel disease. |
1992 |
Lancet |
pmid:1370563
|
First MR |
Transplantation in the nineties. |
1992 |
Transplantation |
pmid:1370734
|
Naito M et al. |
Reversal of multidrug resistance by an immunosuppressive agent FK-506. |
1992 |
Cancer Chemother. Pharmacol. |
pmid:1370765
|
Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Bishop DK and Li W |
Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. |
1992 |
J. Immunol. |
pmid:1371128
|
Hatfield SM and Roehm NW |
Cyclosporine and FK506 inhibition of murine mast cell cytokine production. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1371158
|
Moutabarrik A et al. |
In vitro FK506 kidney tubular cell toxicity. |
1992 |
Transpl. Int. |
pmid:14621743
|
Moutabarrik A et al. |
FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells. |
1992 |
Transpl. Int. |
pmid:14621744
|
Stangl MJ et al. |
The use of FK506 and RS61443 for reversal of small-bowel rejection. |
1992 |
Transpl. Int. |
pmid:14621800
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Jiang H et al. |
Control of humoral and cellular immunity-mediated accelerated heart allograft rejection in sensitized rats by low dose FK 506 and splenectomy. |
1992 |
Transpl. Int. |
pmid:14621859
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs and FK506. |
1992 |
Transpl. Int. |
pmid:14621861
|
Carobbi A et al. |
Synergism of splenectomy and immunosuppressive drugs in prolongation of cardiac xenograft survival. |
1992 |
Transplant. Proc. |
pmid:1373543
|
Ueno M et al. |
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1373546
|
Matsuzaki T et al. |
Liver transplantation for diethylnitrosamine-induced hepatocellular carcinoma in rats. |
1992 |
Transplant. Proc. |
pmid:1373547
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Liu J et al. |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. |
1992 |
Biochemistry |
pmid:1373650
|
Adachi A et al. |
Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. |
1992 |
Intern. Med. |
pmid:1373661
|
de Paulis A et al. |
Anti-inflammatory effect of FK-506 on human skin mast cells. |
1992 |
J. Invest. Dermatol. |
pmid:1281861
|
Wiederrecht G et al. |
Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1376117
|
Bernstein L and Daviss SR |
Organic anxiety disorder with symptoms of akathisia in a patient treated with the immunosuppressant FK506. |
1992 |
Gen Hosp Psychiatry |
pmid:1376291
|
Hatfield SM et al. |
Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1376361
|
Ericzon BG et al. |
The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. |
1992 |
Transplantation |
pmid:1376501
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Yasunami Y et al. |
Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. |
1992 |
Transplant. Proc. |
pmid:1376510
|
Kai N et al. |
A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. |
1992 |
Transplant. Proc. |
pmid:1376511
|
Takaya S et al. |
Liver transplantation in positive cytotoxic crossmatch cases using FK506, high-dose steroids, and prostaglandin E1. |
1992 |
Transplantation |
pmid:1279851
|
Partaledis JA et al. |
Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. |
1992 |
Yeast |
pmid:1279908
|
Ozawa K et al. |
An appraisal of pediatric liver transplantation from living relatives. Initial clinical experiences in 20 pediatric liver transplantations from living relatives as donors. |
1992 |
Ann. Surg. |
pmid:1280074
|
Akutsu I et al. |
[Inhibitory effects of cyclosporin A and FK-506 on eosinophil chemotactic factor activity in culture supernatants of mononuclear cells from asthmatics]. |
1992 |
Arerugi |
pmid:1280086
|
Bergstrand H and Lundquist B |
Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. |
1992 |
Allergy |
pmid:1280915
|
Barry JM |
Immunosuppressive drugs in renal transplantation. A review of the regimens. |
1992 |
Drugs |
pmid:1281071
|
Stiff DD et al. |
Metabolism of FK 506 in differentially induced rat liver microsomes. |
1992 |
Res. Commun. Chem. Pathol. Pharmacol. |
pmid:1281332
|
Bavandi A et al. |
Diet-induced dermatitis response of hairless rats to systemic treatment with cyclosporin A (Sandimmun), cyclosporin H and FK506. |
1992 |
Exp. Dermatol. |
pmid:1285411
|
High KP and Handschumacher RE |
Immunity, microbial pathogenesis, and immunophilins: finding the keys, now where are the locks? |
1992 |
Infect Agents Dis |
pmid:1285413
|
Akutsu I et al. |
[Inhibitory effect of inhaled FK-506 on increased bronchial responsiveness and eosinophil infiltration in the airway mucosa]. |
1992 |
Arerugi |
pmid:1377905
|
Takaori K et al. |
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. |
1992 |
Biotherapy |
pmid:1377926
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Takai K et al. |
Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. |
1992 |
Thymus |
pmid:1378235
|
Dutz JP et al. |
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. |
1992 |
Int. Immunol. |
pmid:1378297
|
First MR |
Renal transplantation for the nephrologist: new immunosuppressive drugs. |
1992 |
Am. J. Kidney Dis. |
pmid:1371201
|
Takada K et al. |
Distribution kinetics of FK-506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A. |
1992 |
Biopharm Drug Dispos |
pmid:1379839
|
Kahan BD |
Cyclosporin A, FK506, rapamycin: the use of a quantitative analytic tool to discriminate immunosuppressive drug interactions. |
1992 |
J. Am. Soc. Nephrol. |
pmid:1379841
|
Lauerma AI et al. |
Inhibition of contact allergy reactions by topical FK506. |
1992 |
Lancet |
pmid:1380111
|
Steiner JP et al. |
High brain densities of the immunophilin FKBP colocalized with calcineurin. |
1992 |
Nature |
pmid:1380130
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Nielsen JB et al. |
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380159
|
Calvo V et al. |
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380162
|
Mittrücker HW and Fleischer B |
Functional localization of an exocytosis-triggering G-protein in human cytotoxic T lymphocytes. |
1992 |
Immunology |
pmid:1383135
|
Yasutomi D et al. |
Inhibition of programmed cell death by cyclosporin A; preferential blocking of cell death induced by signals via TCR/CD3 complex and its mode of action. |
1992 |
Immunology |
pmid:1383138
|
Ruff VA et al. |
Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody. |
1992 |
J. Biol. Chem. |
pmid:1383222
|
Wiederrecht G et al. |
Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex. |
1992 |
J. Biol. Chem. |
pmid:1383226
|
Morris RE |
Immunopharmacology of new xenobiotic immunosuppressive molecules. |
1992 |
Semin. Nephrol. |
pmid:1384096
|
Hendey B et al. |
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. |
1992 |
Science |
pmid:1384129
|
Roberti I et al. |
Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1384182
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Lane BC et al. |
Evaluation of calcineurin's role in the immunosuppressive activity of FK 506, related macrolactams, and cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7679829
|
Celli S et al. |
Long-term survival of heart and liver xenografts with splenectomy and FK 506. |
1993 |
Transplant. Proc. |
pmid:7679830
|
|
Japanese study of FK 506 on kidney transplantation: results of late phase II study. |
1993 |
Transplant. Proc. |
pmid:7679831
|
Kobayashi M et al. |
Production of monoclonal antibody against recombinant human FKBP-12 and subcellular localization of FKBP-12 in human mononuclear and polymorphonuclear cells. |
1993 |
Transplant. Proc. |
pmid:7679832
|
Randhawa PS et al. |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. |
1993 |
Am. J. Surg. Pathol. |
pmid:7680544
|
Xu RX et al. |
Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex. |
1993 |
Biochemistry |
pmid:7680570
|
Egan DA et al. |
Equilibrium denaturation of recombinant human FK binding protein in urea. |
1993 |
Biochemistry |
pmid:7680574
|
Lionetti P et al. |
Activation of mucosal V beta 3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B. |
1993 |
Eur. J. Immunol. |
pmid:7680613
|
Kim YI et al. |
Augmentation of hepatocyte proliferation by immunosuppressant pretherapy is associated with up-regulation of malondialdehyde production. |
1993 |
Res Exp Med (Berl) |
pmid:7506444
|
Hytiroglou P et al. |
FK506 versus cyclosporine as primary immunosuppressive agent for orthotopic liver allograft recipients. Histologic and immunopathologic observations. |
1993 |
Transplantation |
pmid:7506452
|
Ishizuka J et al. |
Effects of FK506 and cyclosporine on dynamic insulin secretion from isolated dog pancreatic islets. |
1993 |
Transplantation |
pmid:7506454
|
Dhar DK et al. |
Effective prevention of ischemic injury of the dearterialized canine liver by FK506 pretreatment. |
1993 |
Transplantation |
pmid:7506456
|
Nakajima J |
[The immunosuppressive effects of FK506 on single lung allotransplantation in Japanese monkey (Macaca fuscata)]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7690829
|
Wenzel-Seifert K and Seifert R |
Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. |
1993 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:7690907
|
Liu J |
FK506 and cyclosporin, molecular probes for studying intracellular signal transduction. |
1993 |
Immunol. Today |
pmid:7691065
|
Mori T et al. |
FK-506: a new immunosuppressive agent, failed to reduce cerebral vasospasm after experimental subarachnoid hemorrhage. |
1993 |
J. Vet. Med. Sci. |
pmid:7691190
|
Takada K et al. |
Distribution characteristics of immunosuppressants FK506 and cyclosporin A in the blood compartment. |
1993 |
Biopharm Drug Dispos |
pmid:7508273
|
Sperr WR et al. |
[Effector cells in allergy: biological principles and new pharmacologic concepts]. |
1993 |
Wien. Klin. Wochenschr. |
pmid:7508662
|
Kawauchi M et al. |
Prolonged survival of orthotopically transplanted heart xenograft in infant baboons. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7693999
|
Shutter LA et al. |
Cortical blindness and white matter lesions in a patient receiving FK506 after liver transplantation. |
1993 |
Neurology |
pmid:7694189
|
Dawson TM et al. |
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7694293
|
Spencer DM et al. |
Controlling signal transduction with synthetic ligands. |
1993 |
Science |
pmid:7694365
|
Ahmed SS et al. |
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7685382
|
Sewell KL |
Immunotherapy and other novel therapies, including biologic response modifiers, apheresis, and dietary modifications. |
1993 |
Curr Opin Rheumatol |
pmid:7685614
|
Wagner JA et al. |
Failure of FK 506 to suppress the T cell-mediated immunity of mice to Listeria monocytogenes. |
1993 |
Clin. Exp. Immunol. |
pmid:7685672
|
Bram RJ et al. |
Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. |
1993 |
Mol. Cell. Biol. |
pmid:7687744
|
Heitman J et al. |
The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. |
1993 |
Mol. Cell. Biol. |
pmid:7687745
|
Hirakawa K et al. |
[The effect of perioperative portal venous inoculation with donor lymphocytes in combination with immunosuppressive agents on rat cardiac allograft survivals]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7688065
|
Entani C et al. |
Effect of a novel immunosuppressant, FK506, on spontaneous lupus nephritis in MRL/MpJ-lpr/lpr mice. |
1993 |
Nephron |
pmid:7688103
|
Namiki Y et al. |
Tautomeric phenomenon of a novel potent immunosuppressant (FK506) in solution. I. Isolation and structure determination of tautomeric compounds. |
1993 |
J. Antibiot. |
pmid:7689551
|
Kondo T et al. |
[Antitumor sensitivity test, subrenal capsule assay using FK-506: preliminary report]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7689693
|
Abu-Elmagd K et al. |
Resolution of severe pyoderma gangrenosum in a patient with streaking leukocyte factor disease after treatment with tacrolimus (FK 506). |
1993 |
Ann. Intern. Med. |
pmid:7689802
|
Christensen BG |
FK-506: its role in immunosuppression. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689803
|
Herold KC et al. |
Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506. |
1993 |
Transplantation |
pmid:7678356
|
Holman MJ et al. |
FK506-associated thrombotic thrombocytopenic purpura. |
1993 |
Transplantation |
pmid:7678357
|
Kawai M et al. |
Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues. |
1993 |
FEBS Lett. |
pmid:7678400
|
Van Duyne GD et al. |
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. |
1993 |
J. Mol. Biol. |
pmid:7678431
|