tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Autoimmune Diseases of the Nervous System D020274 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Hypertensive Encephalopathy D020343 1 associated lipids
Paraneoplastic Syndromes, Nervous System D020361 1 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Peroneal Neuropathies D020427 1 associated lipids
Brain Infarction D020520 17 associated lipids
Stroke D020521 32 associated lipids
Nervous System Autoimmune Disease, Experimental D020721 3 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Intracranial Thrombosis D020767 2 associated lipids
Central Nervous System Viral Diseases D020805 1 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Brachial Plexus Neuritis D020968 2 associated lipids
Lacerations D022125 1 associated lipids
Coronary Stenosis D023921 6 associated lipids
Polyomavirus Infections D027601 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Hyperuricemia D033461 4 associated lipids
Hypoalbuminemia D034141 1 associated lipids
Mastocytosis, Cutaneous D034701 1 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Intestinal Volvulus D045822 1 associated lipids
Ileus D045823 3 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Protoporphyria, Erythropoietic D046351 1 associated lipids
Colitis, Collagenous D046729 1 associated lipids
Hepatic Insufficiency D048550 1 associated lipids
Diabetes Complications D048909 4 associated lipids
Dyslipidemias D050171 7 associated lipids
Atherosclerosis D050197 85 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Lymphohistiocytosis, Hemophagocytic D051359 1 associated lipids
Renal Insufficiency D051437 8 associated lipids
Delayed Graft Function D051799 2 associated lipids
Nocturia D053158 1 associated lipids
Dysuria D053159 1 associated lipids
Posterior Leukoencephalopathy Syndrome D054038 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Dendritic Cell Sarcoma, Interdigitating D054739 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Primary Graft Dysfunction D055031 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Pancreatitis, Graft D055589 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Payabvash S et al. Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. J Postgrad Med pmid:25370549
Akoglu H et al. Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors. J. Nephrol. pmid:23147686
pmid:19200227
Luger T et al. Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs to a new treatment algorithm. Eur J Dermatol pmid:24185493
Park J et al. Persistent generalized lichen nitidus successfully treated with 0.03% tacrolimus ointment. Eur J Dermatol pmid:24184632
Henrique Pinto C et al. Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation. Braz J Infect Dis pmid:27643978
Fernández C et al. Kidney transplantation from HLA-incompatible live donors: Efficiency and outcome of 32 patients after desensitisation. Nefrologia pmid:28734583
Hirohata A et al. Oral tacrolimus for the treatment of generalized morphea. Eur J Dermatol pmid:26679400
López-Oliva MO et al. Switch to belatacept in kidney graft recipients. Nefrologia pmid:28233569
Takahashi Y et al. Pharmacokinetic Profile of Twice- and Once-daily Tacrolimus in Pediatric Kidney Transplant Recipients. Transplant. Proc. pmid:28104153
Shi Y et al. Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. Transplant. Proc. pmid:28104150
Pan D et al. Tacrolimus-associated Diffuse Gastrointestinal Ulcerations and Pathergy: A Case Report. Transplant. Proc. pmid:28104141
Jiménez-Pérez M et al. Everolimus plus mycophenolate mofetil as initial immunosuppression in liver transplantation. Transplant. Proc. pmid:25645779
Polanco N et al. Everolimus-based immunosuppression therapy for BK virus nephropathy. Transplant. Proc. pmid:25645770
Nojima M et al. Immunosuppression Modification by Everolimus With Minimization of Calcineurin Inhibitors Recovers Kidney Graft Function Even in Patients With Very Late Conversion and Also With Poor Graft Function. Transplant. Proc. pmid:28104155
López-Vilella R et al. Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor. Transplant. Proc. pmid:25645789
Tinoco R et al. [A case of de novo inflammatory bowel disease after liver transplantation for cryptogenic cirrhosis]. Gastroenterol Hepatol pmid:26321322
pmid:28590598
pmid:28422431
Al-Amri AM et al. Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. Middle East Afr J Ophthalmol pmid:26957853