tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Myelitis D009187 1 associated lipids
Erythroplasia D004919 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Lacerations D022125 1 associated lipids
Trauma, Nervous System D020196 2 associated lipids
Central Nervous System Viral Diseases D020805 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Hepatopulmonary Syndrome D020065 1 associated lipids
Arm Injuries D001134 1 associated lipids
Lentigo D007911 1 associated lipids
Cardiomyopathy, Restrictive D002313 1 associated lipids
Digestive System Fistula D016154 1 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Miller Fisher Syndrome D019846 1 associated lipids
Colitis, Collagenous D046729 1 associated lipids
Tumor Lysis Syndrome D015275 2 associated lipids
Autoimmune Diseases of the Nervous System D020274 1 associated lipids
Candidiasis, Vulvovaginal D002181 8 associated lipids
Ecthyma, Contagious D004474 1 associated lipids
Poxviridae Infections D011213 1 associated lipids
Seminoma D018239 2 associated lipids
Hepatic Insufficiency D048550 1 associated lipids
Myoclonic Cerebellar Dyssynergia D002527 1 associated lipids
Brachial Plexus Neuritis D020968 2 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Dysuria D053159 1 associated lipids
Mediastinal Diseases D008477 1 associated lipids
Hernia, Ventral D006555 1 associated lipids
Paraneoplastic Syndromes, Nervous System D020361 1 associated lipids
Mite Infestations D008924 1 associated lipids
Feline Infectious Peritonitis D016766 1 associated lipids
Fox-Fordyce Disease D005588 2 associated lipids
Primary Graft Dysfunction D055031 1 associated lipids
Sleep Apnea, Central D020182 1 associated lipids
Protoporphyria, Erythropoietic D046351 1 associated lipids
Digestive System Diseases D004066 3 associated lipids
Pancreatitis, Graft D055589 1 associated lipids
Candidiasis, Invasive D058365 2 associated lipids
Intestinal Volvulus D045822 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Retrognathia D063173 1 associated lipids
Leg Injuries D007869 2 associated lipids
Aneurysm, Dissecting D000784 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Eye Diseases, Hereditary D015785 1 associated lipids
Pruritus Ani D011538 2 associated lipids
AIDS-Associated Nephropathy D016263 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Authors Title Published Journal PubMed Link
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Markus PM et al. Effects of in vivo treatment with FK506 on natural killer cells in rats. 1991 Transplantation pmid:1707562
Kuroki H et al. Synergistic effect of FK 506 and donor-specific blood transfusion on rat skin but not on composite tissue (limb) allograft survival. 1991 Transplant. Proc. pmid:1721436
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DeValeria PA et al. FK 506 fails to reverse moderate cardiac allograft rejection in a canine heterotopic model. 1991 Transplant. Proc. pmid:1721438
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Banerji SS et al. The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. 1991 Mol. Cell. Biol. pmid:1712901
Markus PM et al. FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. 1991 Surgery pmid:1713358
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