tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Paraneoplastic Syndromes, Nervous System D020361 1 associated lipids
Intestinal Fistula D007412 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Nephritis, Hereditary D009394 1 associated lipids
Mastocytosis, Cutaneous D034701 1 associated lipids
Pancreatitis, Graft D055589 1 associated lipids
Hearing Loss, Sudden D003639 1 associated lipids
Rectal Diseases D012002 1 associated lipids
Citrullinemia D020159 1 associated lipids
Pulmonary Veno-Occlusive Disease D011668 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Ramachandran R et al. Tacrolimus combined with corticosteroids versus Modified Ponticelli regimen in treatment of idiopathic membranous nephropathy: Randomized control trial. 2016 Nephrology (Carlton) pmid:26205759
Hurabielle C et al. Certolizumab pegol - A new therapeutic option for refractory disseminated pyoderma gangrenosum associated with Crohn's disease. 2016 J Dermatolog Treat pmid:25909366
Prókai Á et al. Calcineurin-inhibition Results in Upregulation of Local Renin and Subsequent Vascular Endothelial Growth Factor Production in Renal Collecting Ducts. 2016 Transplantation pmid:26502369
Unver Dogan N et al. Investigation of developmental toxicity and teratogenicity of cyclosporine A, tacrolimus and their combinations with prednisolone. 2016 Regul. Toxicol. Pharmacol. pmid:26993750
Garcovich S et al. First report of hereditary Christ-Siemens-Touraine syndrome and non-segmental vitiligo association in a young adult: contraindication for vitiligo treatment. 2016 J Eur Acad Dermatol Venereol pmid:25339629
Ferjani H et al. Combination of tacrolimus and mycophenolate mofetil induces oxidative stress and genotoxicity in spleen and bone marrow of Wistar rats. 2016 Mutat. Res. pmid:27776691
Jahnukainen T et al. The second report of the Nordic Pediatric Renal Transplantation Registry 1997-2012: More infant recipients and improved graft survivals. 2016 Pediatr Transplant pmid:26857893
Fathy M et al. Impact of CYP3A5 and MDR-1 gene polymorphisms on the dose and level of tacrolimus among living-donor liver transplanted patients: single center experience. 2016 Biomarkers pmid:26856709
Størset E et al. Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience. 2016 Nephrology (Carlton) pmid:26854648
Kanda Y et al. A randomized controlled trial of cyclosporine and tacrolimus with strict control of blood concentrations after unrelated bone marrow transplantation. 2016 Bone Marrow Transplant. pmid:26437063
Stocki P et al. Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein. 2016 Mol. Biol. Cell pmid:26764098
Kawamura A et al. Teratocarcinomas Arising from Allogeneic Induced Pluripotent Stem Cell-Derived Cardiac Tissue Constructs Provoked Host Immune Rejection in Mice. 2016 Sci Rep pmid:26763872
Suh SW et al. Risk Factors for the Adverse Events after Conversion from Twice-Daily to Once-Daily Tacrolimus in Stable Liver Transplantation Patients. 2016 J. Korean Med. Sci. pmid:27709847
Yamamoto T et al. Tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis: a retrospective observational study. 2016 Aliment. Pharmacol. Ther. pmid:26762838
Kim JM et al. Immunosuppression status of liver transplant recipients with hepatitis C affects biopsy-proven acute rejection. 2016 Clin Mol Hepatol pmid:27729628
Michael M et al. Outcomes of two-drug maintenance immunosuppression for pediatric renal transplantation: 10-yr follow-up in a single center. 2016 Pediatr Transplant pmid:26916966
Ueda Y et al. Interstitial cystitis associated with primary Sjögren's syndrome successfully treated with a combination of tacrolimus and corticosteroid: A case report and literature review. 2016 Mod Rheumatol pmid:24720552
Kabat-Koperska J et al. The influence of exposure to immunosuppressive treatment during pregnancy on renal function and rate of apoptosis in native kidneys of female Wistar rats. 2016 Apoptosis pmid:27586504
Singh JA et al. Treatments for Lupus Nephritis: A Systematic Review and Network Metaanalysis. 2016 J. Rheumatol. pmid:27585688
Saito S et al. Role of Paternal Antigen-Specific Treg Cells in Successful Implantation. 2016 Am. J. Reprod. Immunol. pmid:26706630
Tamaki M et al. Fungal meningitis caused by Lomentospora prolificans after allogeneic hematopoietic stem cell transplantation. 2016 Transpl Infect Dis pmid:27258644
Orr C et al. Quantifying Insulin Therapy Requirements to Preserve Islet Graft Function Following Islet Transplantation. 2016 Cell Transplant pmid:25853639
Thomas KS et al. Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study. 2016 J. Am. Acad. Dermatol. pmid:27502313
Yaowakulpatana K et al. Impact of CYP3A5 polymorphism on trough concentrations and outcomes of tacrolimus minimization during the early period after kidney transplantation. 2016 Eur. J. Clin. Pharmacol. pmid:26635230
Shuker N et al. Pretransplant Tacrolimus Dose Requirements Predict Early Posttransplant Dose Requirements in Blood Group AB0-Incompatible Kidney Transplant Recipients. 2016 Ther Drug Monit pmid:26630539
Gastaca M et al. Favorable longterm outcomes of liver transplant recipients treated de novo with once-daily tacrolimus: Results of a single-center cohort. 2016 Liver Transpl. pmid:27434676
Genvigir FD et al. Influence of the CYP3A4/5 genetic score and ABCB1 polymorphisms on tacrolimus exposure and renal function in Brazilian kidney transplant patients. 2016 Pharmacogenet. Genomics pmid:27434656
Ogura Y et al. Early Conversion From Twice-Daily Tacrolimus to Prolonged-Release Tacrolimus in Liver Transplantation: A Single-Center Experience. 2016 Ann. Transplant. pmid:27432248
Qi XM et al. FK506 reduces albuminuria through improving podocyte nephrin and podocin expression in diabetic rats. 2016 Inflamm. Res. pmid:26566632
Lee HK et al. Expression of Endoplasmic Reticulum-Mediated Stress Proteins in FK506-Treated T-Lymphocytes. 2016 Transplant. Proc. pmid:27320607
Asavakarn S et al. Systematic Pharmaceutical Educational Approach to Enhance Drug Adherence in Liver Transplant Recipients. 2016 Transplant. Proc. pmid:27320587
Limsrichamrern S et al. Correlation of Hematocrit and Tacrolimus Level in Liver Transplant Recipients. 2016 Transplant. Proc. pmid:27320581
Mo S et al. Improvement of FK506 Production in the High-Yielding Strain Streptomyces sp. RM7011 by Engineering the Supply of Allylmalonyl-CoA Through a Combination of Genetic and Chemical Approach. 2016 J. Microbiol. Biotechnol. pmid:26502733
Yesilipek MA et al. Haploidentical hematopoietic stem cell transplantation with post-transplant high-dose cyclophosphamide in high-risk children: A single-center study. 2016 Pediatr Transplant pmid:26707539
Sobiak J et al. Pharmacokinetics of mycophenolate sodium co-administered with tacrolimus in the first year after renal transplantation. 2016 Eur J Drug Metab Pharmacokinet pmid:25663618
Sharma P et al. Protein Phosphatase 1-α Regulates AS160 Ser588 and Thr642 Dephosphorylation in Skeletal Muscle. 2016 Diabetes pmid:27246912
Medeiros M et al. Are Tacrolimus Pharmacokinetics Affected by Nephrotic Stage? 2016 Ther Drug Monit pmid:27167176
Nitta D et al. Successful Pregnancy and Delivery in a Heart Transplantation Recipient. 2016 Int Heart J pmid:27150004
Ban YH et al. The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects. 2016 J. Ind. Microbiol. Biotechnol. pmid:26342319
Abud TB et al. A Clinical Trial Comparing the Safety and Efficacy of Topical Tacrolimus versus Methylprednisolone in Ocular Graft-versus-Host Disease. 2016 Ophthalmology pmid:27086024
Nijhoff MF et al. Glycemic Stability Through Islet-After-Kidney Transplantation Using an Alemtuzumab-Based Induction Regimen and Long-Term Triple-Maintenance Immunosuppression. 2016 Am. J. Transplant. pmid:26288226
Fujii S et al. Prior activation of inositol 1,4,5-trisphosphate receptors suppresses the subsequent induction of long-term potentiation in hippocampal CA1 neurons. 2016 Learn. Mem. pmid:27084928
Han SS et al. Monitoring the Intracellular Tacrolimus Concentration in Kidney Transplant Recipients with Stable Graft Function. 2016 PLoS ONE pmid:27082871
Tannuri AC et al. Prognostic factors for the evolution and reversibility of chronic rejection in pediatric liver transplantation. 2016 Clinics (Sao Paulo) pmid:27166772
Tariciotti L et al. Everolimus and Advagraf Ab Initio in Combined Liver and Kidney Transplant With Donor-Specific Antibodies: A Case Report. 2016 Transplant. Proc. pmid:27932158
Ikeda M et al. Successful Second Allogeneic Stem Cell Transplantation From a Sibling Donor for Relapse of Myelodysplastic Syndrome in a Recipient of a Renal Transplant From His Mother: Case Report. 2016 Transplant. Proc. pmid:27932152
Kolonko A et al. Successful Preemptive Kidney Transplantation With Rituximab Induction in a Patient With Focal Segmental Glomerulosclerosis and Massive Nephrotic Syndrome: A Case Report. 2016 Transplant. Proc. pmid:27932154
Thölking G et al. Tacrolimus Concentration/Dose Ratio is Associated with Renal Function After Liver Transplantation. 2016 Ann. Transplant. pmid:27003330
Krämer BK et al. Efficacy and safety of tacrolimus compared with ciclosporin-A in renal transplantation: 7-year observational results. 2016 Transpl. Int. pmid:26565071
Janicki JJ et al. Potential Effect of Liposomes and Liposome-Encapsulated Botulinum Toxin and Tacrolimus in the Treatment of Bladder Dysfunction. 2016 Toxins (Basel) pmid:26999210