tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Sleep Apnea, Central D020182 1 associated lipids
Orchitis D009920 1 associated lipids
Phyllodes Tumor D003557 1 associated lipids
Meningitis, Fungal D016921 1 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Cardiomyopathy, Restrictive D002313 1 associated lipids
Paraparesis, Tropical Spastic D015493 1 associated lipids
Neurodermatitis D009450 1 associated lipids
Posterior Leukoencephalopathy Syndrome D054038 1 associated lipids
Ecthyma, Contagious D004474 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Shapiro R et al. Posttransplant lymphoproliferative disorders in adult and pediatric renal transplant patients receiving tacrolimus-based immunosuppression. 1999 Transplantation pmid:10628763
Haines DD et al. Cardioprotective effects of the calcineurin inhibitor FK506 and the PAF receptor antagonist and free radical scavenger, EGb 761, in isolated ischemic/reperfused rat hearts. 2000 J. Cardiovasc. Pharmacol. pmid:10630731
Paul LC Dialysis and transplantation. 1999 Curr. Opin. Nephrol. Hypertens. pmid:10630810
Vanrenterghem YF Which calcineurin inhibitor is preferred in renal transplantation: tacrolimus or cyclosporine? 1999 Curr. Opin. Nephrol. Hypertens. pmid:10630811
Wang-Fan W et al. Application of centrifugal counter-current chromatography to the separation of macrolide antibiotic analogues. I. Selection of solvent systems based on solubility and partition coefficient investigations. 1999 J Chromatogr A pmid:10630872
Furutani M et al. FK506 binding protein from a thermophilic archaeon, Methanococcus thermolithotrophicus, has chaperone-like activity in vitro. 2000 Biochemistry pmid:10631007
Thiers BH Topical tacrolimus: treatment failure in a patient with alopecia areata. 2000 Arch Dermatol pmid:10632221
Lipper GM et al. Recent therapeutic advances in dermatology. 2000 JAMA pmid:10634322
Richter-Hintz D et al. Topical tacrolimus (FK 506) is effective in the treatment of pyoderma gangrenosum. 2000 J. Am. Acad. Dermatol. pmid:10642695
Bekersky I et al. Dose linearity after oral administration of tacrolimus 1-mg capsules at doses of 3, 7, and 10 mg. 1999 Clin Ther pmid:10645753
Fuseler JW et al. FK506 attenuates developing and established joint inflammation and suppresses interleukin 6 and nitric oxide expression in bacterial cell wall induced polyarthritis. 2000 J. Rheumatol. pmid:10648038
Schrama YC et al. Concealed by veils. 2000 Nephrol. Dial. Transplant. pmid:10648679
Reddy KS et al. Simultaneous kidney-pancreas transplantation without antilymphocyte induction. 2000 Transplantation pmid:10653379
Jain A et al. Conversion to neoral for neurotoxicity after primary adult liver transplantation under tacrolimus. 2000 Transplantation pmid:10653398
Wu GS et al. Deoxyspergualin delays xenograft rejection in the guinea pig-to-C6-deficient rat heart transplantation model. 1999 Transpl. Int. pmid:10654352
Novelli M et al. Oral absorption of tacrolimus in children with intestinal failure due to short or absent small bowel. 1999 Transpl. Int. pmid:10654359
Tamura J et al. [The role of protein kinases and phosphatases in erythroid colony formation of elderly]. 1999 Nihon Ronen Igakkai Zasshi pmid:10655734
Tamura A et al. Immunosuppressive therapy using FTY720 combined with tacrolimus in rat liver transplantation. 2000 Surgery pmid:10660758
Schuppe H et al. Topical tacrolimus for recalcitrant leg ulcer in rheumatoid arthritis. 2000 Rheumatology (Oxford) pmid:10662882
McAlister VC et al. Sirolimus-tacrolimus combination immunosuppression. 2000 Lancet pmid:10665560