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Mechanism of action of rapamycin: new insights into the regulation of G1-phase progression in eukaryotic cells. |
1995 |
Prog Cell Cycle Res |
pmid:9552353
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Fruman DA et al. |
The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. |
1995 |
J. Immunol. |
pmid:7530743
|
Neuhaus P et al. |
Comparison of FK506- and cyclosporine-based immunosuppression in primary orthotopic liver transplantation. A single center experience. |
1995 |
Transplantation |
pmid:7530868
|
Heeckt PF et al. |
Functional impairment of enteric smooth muscle and nerves caused by chronic intestinal allograft rejection regresses after FK506 rescue. |
1995 |
Transplantation |
pmid:7530870
|
Gruessner RW et al. |
A prospective study of FK506 versus CsA and pig ATG in a porcine model of small bowel transplantation. |
1995 |
Transplantation |
pmid:7530871
|
Todo S et al. |
Abdominal multivisceral transplantation. |
1995 |
Transplantation |
pmid:7530873
|
Hamasaki Y et al. |
Inhibition of leukotriene production by FK506 in rat basophilic leukemia-1 cells. |
1995 |
Pharmacology |
pmid:7538218
|
Wera S et al. |
Rapamycin, FK506 and cyclosporin A inhibit human prolactin gene expression. |
1995 |
FEBS Lett. |
pmid:7530217
|
Ning YM and Sanchez ER |
Stabilization in vitro of the untransformed glucocorticoid receptor complex of S49 lymphocytes by the immunophilin ligand FK506. |
1995 |
J. Steroid Biochem. Mol. Biol. |
pmid:7532989
|
Fruman DA et al. |
FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. |
1995 |
Eur. J. Immunol. |
pmid:7533090
|
Cameron AM et al. |
Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7533300
|
Shapiro R et al. |
A prospective randomized trial of FK506-based immunosuppression after renal transplantation. |
1995 |
Transplantation |
pmid:7533343
|
Cox KL et al. |
An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation. |
1995 |
Transplantation |
pmid:7533344
|
McDiarmid SV et al. |
FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial. |
1995 |
Transplantation |
pmid:7533345
|
Jain AB et al. |
One thousand consecutive primary orthotopic liver transplants under FK 506: survival and adverse events. |
1995 |
Transplant. Proc. |
pmid:7533353
|
Grobecker HF et al. |
Cyclosporine A-induced hypertension in SHR and WKY: role of the sympatho-adrenal system. |
1995 |
Clin Exp Pharmacol Physiol Suppl |
pmid:9072458
|
Watanabe K et al. |
Factors influencing long-term operational tolerance in dogs treated with fractionated lymphoid irradiation, donor bone marrow cell infusion and FK506. |
1995 |
Transplant. Proc. |
pmid:7533389
|
Wennberg L et al. |
Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection. |
1995 |
Transplant. Proc. |
pmid:7533391
|
Tanaka M et al. |
Effect of anticomplement agent K-76 COOH in hamster-to-rat and guinea pig-to-rat xenotransplantation. |
1995 |
Transplant. Proc. |
pmid:7533392
|
Tsugita M et al. |
Prevention of sensitization and hyperacute rejection in liver and heart xenografts by FK 506 plus donor antigens. |
1995 |
Transplant. Proc. |
pmid:7533393
|
Sakimoto H et al. |
Prolonged survival of hamster-to-rat pancreas xenografts by FK 506 and splenectomy. |
1995 |
Transplant. Proc. |
pmid:7533394
|
Celli S et al. |
Mechanisms of protection from humoral rejection by a xenografted liver. |
1995 |
Transplant. Proc. |
pmid:7533395
|
Kuroki H and Ikuta Y |
Nerve regeneration of vascularized rat limb allograft and functional recovery of long-term graft survivals treated by short course of FK 506 or cyclosporine. |
1995 |
Transplant. Proc. |
pmid:7533405
|
Ko S et al. |
Significance of newly developed liposomal FK 506 in canine liver transplantation. |
1995 |
Transplant. Proc. |
pmid:7533406
|
Gregory CR et al. |
Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement. |
1995 |
Transplantation |
pmid:7533955
|
Egawa H et al. |
Isolated alkaline phosphatemia following pediatric liver transplantation in the FK506 ERA. |
1995 |
Transplantation |
pmid:7533958
|
Molenaar JC |
[Transplantation of the small intestine]. |
1995 |
Ned Tijdschr Geneeskd |
pmid:7534380
|
Swenson JM et al. |
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506. |
1995 |
J. Am. Coll. Cardiol. |
pmid:7534779
|
Sen J et al. |
Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. |
1995 |
J. Immunol. |
pmid:7534792
|
Hodgkiss JP and Kelly JS |
Only 'de novo' long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex. |
1995 |
Brain Res. |
pmid:8821755
|
Petrides AS |
[Do immunosuppressive agents really impair glucose tolerance in liver transplant patients?]. |
1995 |
Z Gastroenterol |
pmid:7571761
|
Thomson AW and Bonham CA |
Inhibition of T lymphocyte activation and apoptotic cell death by cyclosporin A and tacrolimus (FK506). Its relevance to therapy of HIV infection. |
1995 |
Adv. Exp. Med. Biol. |
pmid:7572394
|
Paterson JM et al. |
Control of a novel adenylyl cyclase by calcineurin. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7575502
|
Cunningham EB |
The human erythrocyte membrane contains a novel 12-kDa inositolphosphate-binding protein that is an immunophilin. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7575593
|
Ellis D |
Clinical use of tacrolimus (FK-506) in infants and children with renal transplants. |
1995 |
Pediatr. Nephrol. |
pmid:7577418
|
Masaki Y et al. |
Cellular basis of acquired immunologic tolerance following total bowel transplantation in rats. I. Relation between donor lymphocyte chimerism and host-cell-mediated immunity. |
1995 |
Transplant. Proc. |
pmid:7536971
|
Furuke K et al. |
Suppression of adult T cell leukemia-derived factor/human thioredoxin induction by FK506 and cyclosporin A: a new mechanism of immune modulation via redox control. |
1995 |
Int. Immunol. |
pmid:7577807
|
Masaki Y et al. |
Cellular basis of immunologic tolerance following total bowel transplantation in rats. II. Dominant role of suppressor T cells in adoptive transfer of acquired tolerance to vascularized allografts. |
1995 |
Transplant. Proc. |
pmid:7536972
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Suzuki H et al. |
Spleen grafting might induce transplantation tolerance in rats. |
1995 |
Transplant. Proc. |
pmid:7536973
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Shapiro R et al. |
FK506 in pediatric kidney transplantation--primary and rescue experience. |
1995 |
Pediatr. Nephrol. |
pmid:7492486
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Mehta BA et al. |
Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells. |
1995 |
Blood |
pmid:7579455
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Ito A et al. |
Induction of tolerance in rat cardiac allograft model by intrathymic injection of donor bone marrow cells. |
1995 |
Transplant. Proc. |
pmid:7536974
|
Coss MC et al. |
Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65). |
1995 |
J. Biol. Chem. |
pmid:7493967
|
Büttemeyer R et al. |
Peripheral nerve allotransplant immunosuppressed with FK 506: preliminary results. |
1995 |
Transplant. Proc. |
pmid:7536979
|
Lee MJ et al. |
Physicochemical, pharmacokinetic and pharmacodynamic evaluation of liposomal tacrolimus (FK 506) in rats. |
1995 |
Pharm. Res. |
pmid:7494802
|
Venkataramanan R et al. |
Clinical pharmacokinetics of tacrolimus. |
1995 |
Clin Pharmacokinet |
pmid:8787947
|
Arita S et al. |
Effect of FK 506 in experimental pancreas transplantation. |
1995 |
Transplant. Proc. |
pmid:7536980
|
Zhao Y and Iwata M |
Cross-linking of the TCR-CD3 complex with CD4, CD8 or LFA-1 induces an anti-apoptotic signal in thymocytes: the signal is canceled by FK506. |
1995 |
Int. Immunol. |
pmid:7495746
|
Aono T et al. |
Minimal threshold of FK 506 for enhancing liver regeneration in thymectomized rats. |
1995 |
Transplant. Proc. |
pmid:7536981
|
Teraoka S et al. |
[Present status and problems in clinical application of tacrolimus(FK506)]. |
1995 |
Nihon Rinsho Meneki Gakkai Kaishi |
pmid:8963787
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Yamamoto S et al. |
Cross-species transplantation of photoreceptors with tacrolimus hydrate (FK506) treatment. |
1995 |
Jpn. J. Ophthalmol. |
pmid:8926639
|
Freeman DJ et al. |
Stability of FK 506 in whole blood samples. |
1995 |
Ther Drug Monit |
pmid:7542810
|
Strumph P et al. |
The effect of FK506 on glycemic response as assessed by the hyperglycemic clamp technique. |
1995 |
Transplantation |
pmid:7542815
|
Sihra TS et al. |
A role for calcineurin (protein phosphatase-2B) in the regulation of glutamate release. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7542882
|
Dumont FJ et al. |
Increased LFA-1-mediated homotypic cell adhesion is associated with the G1 growth arrest induced by rapamycin in a T cell lymphoma. |
1995 |
Exp. Cell Res. |
pmid:7543051
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Zhao Y et al. |
Calcineurin activation protects T cells from glucocorticoid-induced apoptosis. |
1995 |
J. Immunol. |
pmid:7539018
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Corey HE et al. |
Renal allograft rejection in children and young adults: the Banff classification. |
1995 |
Pediatr. Nephrol. |
pmid:7543274
|
Bronsther O et al. |
Liver transplantation for HBV-related disease under immunosuppression with tacrolimus: an experience with 78 consecutive cases. |
1995 |
J Okla State Med Assoc |
pmid:7539077
|
Griffith JP et al. |
X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. |
1995 |
Cell |
pmid:7543369
|
Chen J et al. |
Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7539137
|
Prud'homme GJ et al. |
Effects of cyclosporin A, rapamycin, and FK520 on peripheral T-cell deletion and anergy. |
1995 |
Cell. Immunol. |
pmid:7543371
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Renoir JM et al. |
Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated gene expression. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7539138
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Migita K et al. |
FK506 augments activation-induced programmed cell death of T lymphocytes in vivo. |
1995 |
J. Clin. Invest. |
pmid:7543492
|
Rodriguez Rilo HL et al. |
Rapid hair regrowth in refractory alopecia universalis associated with autoimmune disease following liver transplantation and tacrolimus (FK506) therapy. |
1995 |
Transplantation |
pmid:7539169
|
Lhoëst G et al. |
The in vitro immunosuppressive activity of the C15-demethylated metabolite of FK-506 is governed by ring- and open-chain tautomerism effects. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7543569
|
Schleibner S et al. |
FK 506 versus cyclosporin in the prevention of renal allograft rejection--European pilot study: six-week results. |
1995 |
Transpl. Int. |
pmid:7539270
|
Ko S et al. |
The enhanced immunosuppressive efficacy of newly developed liposomal FK506 in canine liver transplantation. |
1995 |
Transplantation |
pmid:7539553
|
Fealy MJ et al. |
Association of down-regulation of cytokine activity with rat hind limb allograft survival. |
1995 |
Transplantation |
pmid:7539555
|
Sher LS and Makowka L |
Immunosuppression: now we have choices. |
1995 |
Hepatology |
pmid:7544759
|
Perrot-Applanat M et al. |
The 59 kDa FK506-binding protein, a 90 kDa heat shock protein binding immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus. |
1995 |
J. Cell. Sci. |
pmid:7544801
|
Hibi S et al. |
Severe rhabdomyolysis associated with tacrolimus. |
1995 |
Lancet |
pmid:7544861
|
Kinoshita I et al. |
Myoblast allotransplantation in primates. |
1995 |
Muscle Nerve |
pmid:7544871
|
Rao PN et al. |
Reduction of FK-506 requirements by combination with polyethylene glycol superoxide dismutase in orthotopic rat liver transplantation. |
1995 |
J. Allergy Clin. Immunol. |
pmid:7541060
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Monsour HP et al. |
Renal insufficiency and hypertension as long-term complications in liver transplantation. |
1995 |
Semin. Liver Dis. |
pmid:7544917
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Gold BG et al. |
The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve. |
1995 |
J. Neurosci. |
pmid:7472502
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Varela E |
[Small bowel transplantation]. |
1995 |
Acta Gastroenterol. Latinoam. |
pmid:7544939
|
Takahara S and Okuyama A |
[Blood level monitoring of immunosuppressive agent]. |
1995 |
Rinsho Byori |
pmid:7474422
|
Taler SJ et al. |
Loss of nocturnal blood pressure fall after liver transplantation during immunosuppressive therapy. |
1995 |
Am. J. Hypertens. |
pmid:7544983
|
Morris RE and Brown BW |
Tacrolimus for prevention of liver allograft rejection: clinical trials and tribulations. |
1995 |
Lancet |
pmid:7475764
|
Starzl TE et al. |
Randomised trialomania? The multicentre liver transplant trials of tacrolimus. |
1995 |
Lancet |
pmid:7475777
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Milad M et al. |
Interaction of the progesterone receptor with binding proteins for FK506 and cyclosporin A. |
1995 |
Mol. Endocrinol. |
pmid:7476967
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Zhang J and Steiner JP |
Nitric oxide synthase, immunophilins and poly(ADP-ribose) synthetase: novel targets for the development of neuroprotective drugs. |
1995 |
Neurol. Res. |
pmid:7477744
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Jindal RM and Popescu I |
Renal dysfunction associated with liver transplantation. |
1995 |
Postgrad Med J |
pmid:7479462
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Zhu D et al. |
Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae. |
1995 |
J. Biol. Chem. |
pmid:7559604
|
Farcasanu IC et al. |
Protein phosphatase 2B of Saccharomyces cerevisiae is required for tolerance to manganese, in blocking the entry of ions into the cells. |
1995 |
Eur. J. Biochem. |
pmid:7588708
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Stemmer PM et al. |
Factors responsible for the Ca(2+)-dependent inactivation of calcineurin in brain. |
1995 |
FEBS Lett. |
pmid:7589543
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Hadad SJ et al. |
FK 506: effects on glomerular hemodynamics and on mesangial cells in culture. |
1995 |
Kidney Int. |
pmid:7564092
|
Zhu X et al. |
Enhancing and suppressive effects of immunosuppressants cyclosporin A, FK506, and KM2210 on the colony formation of murine bone marrow cells. |
1995 |
Ann. Hematol. |
pmid:8534762
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Mazur P et al. |
Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase. |
1995 |
Mol. Cell. Biol. |
pmid:7565718
|
Ockenfels HM et al. |
Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis. |
1995 |
Dermatology (Basel) |
pmid:8534940
|
Spencer DM et al. |
A general strategy for producing conditional alleles of Src-like tyrosine kinases. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7568222
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Orengo CA et al. |
Structural similarity between the pleckstrin homology domain and verotoxin: the problem of measuring and evaluating structural similarity. |
1995 |
Protein Sci. |
pmid:8535234
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Holsinger LJ et al. |
Signal transduction in T lymphocytes using a conditional allele of Sos. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7568223
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Ihara H et al. |
Intra- and interindividual variation in the pharmacokinetics of tacrolimus (FK506) in kidney transplant recipients--importance of trough level as a practical indicator. |
1995 |
Int. J. Urol. |
pmid:8536129
|
Vilquin JT et al. |
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer. |
1995 |
Hum. Gene Ther. |
pmid:8573612
|
Sano T et al. |
FK506 and cyclosporin A inhibit granulocyte/macrophage colony-stimulating factor production by mononuclear cells in asthma. |
1995 |
Eur. Respir. J. |
pmid:8575571
|
Faerman CH and Karplus PA |
Consensus preferred hydration sites in six FKBP12-drug complexes. |
1995 |
Proteins |
pmid:8539241
|
Groth CG |
Immunosuppressive regimens of tomorrow. |
1995 |
Transplant. Proc. |
pmid:8539797
|
Sekigawa I et al. |
Inhibitory effect of the immunosuppressant FK506 on apoptotic cell death induced by HIV-1 gp120. |
1995 |
J. Clin. Immunol. |
pmid:8576317
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Hariharan S et al. |
Conversion from cyclosporine to tacrolimus after pancreas transplantation. |
1995 |
Transplant. Proc. |
pmid:8539799
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