Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cao KJ et al. | [Immunosuppressive therapy after human lung transplantation]. | 2007 | Zhonghua Wai Ke Za Zhi | pmid:17845780 |
Li YX et al. | [Preliminary experience with Campath 1H induction combined with low-dose monotherapy of tacrolimus in small bowel transplantation]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19961008 |
Lü DC et al. | [An experimental study of the neuroprotective effect of FK506 on acute spinal cord injury in dogs]. | 2005 | Zhonghua Wai Ke Za Zhi | pmid:16194341 |
Zhao X et al. | [A retrospective cohort study regarding the effect of sirolimus-based immunosuppression protocol on the long-term survival of hepatocellular carcinoma patients after liver transplantation]. | 2014 | Zhonghua Wai Ke Za Zhi | pmid:24924566 |
Ju WQ et al. | [Two-dose steroid combined with two-dose daclizumab and tacrolimus regimen in liver transplant recipients]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19781270 |
Hu AB et al. | [Evaluation of efficacy and safety on steroid withdraw at the seventh day after liver transplantation]. | 2008 | Zhonghua Wai Ke Za Zhi | pmid:19094670 |
Yang FC et al. | [Influence of combined cyclosporine A and tacrolimus with 5-fluorouracil on hepatocellular carcinoma rats]. | 2003 | Zhonghua Wai Ke Za Zhi | pmid:12895356 |
DU C et al. | [In vitro effects of tacrolimus on platelet function]. | 2014 | Zhonghua Xue Ye Xue Za Zhi | pmid:25339327 |
Chen F et al. | [Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria]. | 2015 | Zhonghua Xue Ye Xue Za Zhi | pmid:26759101 |
Sun J et al. | [A preliminary study on the biological characteristics and function of tolerogenic dendritic cells induced by tacrolimus]. | 2014 | Zhonghua Xue Ye Xue Za Zhi | pmid:24985179 |