| MeSH term | MeSH ID | Detail |
|---|---|---|
| Amyloid Neuropathies | D017772 | 1 associated lipids |
| Cervical Intraepithelial Neoplasia | D018290 | 1 associated lipids |
| Migraine with Aura | D020325 | 1 associated lipids |
| Flaviviridae Infections | D018178 | 1 associated lipids |
| Idiopathic Interstitial Pneumonias | D054988 | 1 associated lipids |
| Dysuria | D053159 | 1 associated lipids |
| Denys-Drash Syndrome | D030321 | 1 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Sleep Apnea, Central | D020182 | 1 associated lipids |
| Orchitis | D009920 | 1 associated lipids |
| Phyllodes Tumor | D003557 | 1 associated lipids |
| Meningitis, Fungal | D016921 | 1 associated lipids |
| Malocclusion, Angle Class II | D008312 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cavaillé-Coll MW and Elashoff MR | Commentary on a comparison of tacrolimus and cyclosporine for immunosuppression after cadaveric renal transplantation. | 1998 | Transplantation | pmid:9448161 |
| Burroughs TE et al. | Diabetic complications associated with new-onset diabetes mellitus in renal transplant recipients. | 2007 | Transplantation | pmid:17452891 |
| Fung JJ | Tacrolimus and transplantation: a decade in review. | 2004 | Transplantation | pmid:15201685 |
| Busuttil RW and Lake JR | Role of tacrolimus in the evolution of liver transplantation. | 2004 | Transplantation | pmid:15201686 |
| Gjertson DW et al. | The relative effects of FK506 and cyclosporine on short- and long-term kidney graft survival. | 1995 | Transplantation | pmid:8545861 |
| Vincenti F | A decade of progress in kidney transplantation. | 2004 | Transplantation | pmid:15201687 |
| Bunnapradist S et al. | Graft survival following living-donor renal transplantation: a comparison of tacrolimus and cyclosporine microemulsion with mycophenolate mofetil and steroids. | 2003 | Transplantation | pmid:12865780 |
| Pfitzmann R et al. | Mycophenolatemofetil for immunosuppression after liver transplantation: a follow-up study of 191 patients. | 2003 | Transplantation | pmid:12865798 |
| Ciancio G et al. | Randomized trial of three induction antibodies in kidney transplantation: long-term results. | 2014 | Transplantation | pmid:24477186 |
| Hougardy JM et al. | The once-daily formulation of tacrolimus: a step forward in kidney transplantation? | 2012 | Transplantation | pmid:22234346 |
| Hashimoto T et al. | Treatment with FK506 prevents rejection of rat colon allografts. | 1994 | Transplantation | pmid:7516586 |
| Krentz AJ et al. | Postoperative glucose metabolism in liver transplant recipients. A two-year prospective randomized study of cyclosporine versus FK506. | 1994 | Transplantation | pmid:7516590 |
| Heffron TG et al. | Pediatric liver transplantation with daclizumab induction. | 2003 | Transplantation | pmid:12829908 |
| Gonwa T et al. | Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at three years. | 2003 | Transplantation | pmid:12829910 |
| Krentz AJ | Posttransplantation Diabetes Mellitus in FK-506-Treated Renal Transplant Recipients: Analysis of Incidence and Risk Factors. Transplantation 2001; 72: 1655. | 2001 | Transplantation | pmid:11726815 |
| Andrés A et al. | A randomized trial comparing renal function in older kidney transplant patients following delayed versus immediate tacrolimus administration. | 2009 | Transplantation | pmid:19898206 |
| Fisher NC et al. | Chronic renal failure following liver transplantation: a retrospective analysis. | 1998 | Transplantation | pmid:9679823 |
| Ericzon BG et al. | The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. | 1992 | Transplantation | pmid:1376501 |
| Sanchez-Campos S et al. | Cholestasis and alterations of glutathione metabolism induced by tacrolimus (FK506) in the rat. | 1998 | Transplantation | pmid:9679826 |
| Solez K et al. | Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: a report of the FK506 Kidney Transplant Study Group. | 1998 | Transplantation | pmid:9884269 |
| Bronster DJ et al. | Tacrolimus-associated mutism after orthotopic liver transplantation. | 2000 | Transplantation | pmid:11014653 |
| Saliba F et al. | Corticosteroid-Sparing and Optimization of Mycophenolic Acid Exposure in Liver Transplant Recipients Receiving Mycophenolate Mofetil and Tacrolimus: A Randomized, Multicenter Study. | 2016 | Transplantation | pmid:27454919 |
| Nobori S et al. | Long-term acceptance of fully allogeneic cardiac grafts by cotransplantation of vascularized thymus in miniature swine. | 2006 | Transplantation | pmid:16421473 |
| Theruvath TP et al. | Control of antidonor antibody production with tacrolimus and mycophenolate mofetil in renal allograft recipients with chronic rejection. | 2001 | Transplantation | pmid:11468538 |
| Zervos XA et al. | Comparison of tacrolimus with microemulsion cyclosporine as primary immunosuppression in hepatitis C patients after liver transplantation. | 1998 | Transplantation | pmid:9583863 |
| Muraki T et al. | Effects of cyclosporine and FK506 on in vitro high shear-induced platelet reactivity in rat and human non-anticoagulated blood. | 1998 | Transplantation | pmid:9583878 |
| Luan FL et al. | New-onset diabetes mellitus in kidney transplant recipients discharged on steroid-free immunosuppression. | 2011 | Transplantation | pmid:21242885 |
| Bronster DJ et al. | Demyelinating sensorimotor polyneuropathy after administration of FK506. | 1995 | Transplantation | pmid:7535959 |
| Neumann UP et al. | Significance of a T-lymphocytotoxic crossmatch in liver and combined liver-kidney transplantation. | 2001 | Transplantation | pmid:11374419 |
| Andries S et al. | Posttransplant immune hepatitis in pediatric liver transplant recipients: incidence and maintenance therapy with azathioprine. | 2001 | Transplantation | pmid:11477351 |
| Shapiro R et al. | Alemtuzumab preconditioning with tacrolimus monotherapy-the impact of serial monitoring for donor-specific antibody. | 2008 | Transplantation | pmid:18431232 |
| Taler SJ et al. | Role of steroid dose in hypertension early after liver transplantation with tacrolimus (FK506) and cyclosporine. | 1996 | Transplantation | pmid:8970613 |
| Chakrabarti P et al. | Outcome after steroid withdrawal in pediatric renal transplant patients receiving tacrolimus-based immunosuppression. | 2000 | Transplantation | pmid:11003353 |
| Meier M et al. | Slowing the progression of chronic allograft nephropathy by conversion from cyclosporine to tacrolimus: a randomized controlled trial. | 2006 | Transplantation | pmid:16612281 |
| Inoue T et al. | Lesser reduction in bone mineral density by the immunosuppressant, FK506, compared with cyclosporine in rats. | 2000 | Transplantation | pmid:11003356 |
| Brunet M et al. | Sequential determination of pharmacokinetics and pharmacodynamics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil. | 2006 | Transplantation | pmid:16495801 |
| Holt S and Moore K | Different effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects. | 2002 | Transplantation | pmid:11907407 |
| Hougardy JM et al. | Conversion from Prograf to Advagraf among kidney transplant recipients results in sustained decrease in tacrolimus exposure. | 2011 | Transplantation | pmid:21192316 |
| Blakolmer K et al. | Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging. | 2000 | Transplantation | pmid:10868635 |
| Apanay DC et al. | Cyclosporine increases the oxidizability of low-density lipoproteins in renal transplant recipients. | 1994 | Transplantation | pmid:7524202 |
| Neuhaus P et al. | Quadruple tacrolimus-based induction therapy including azathioprine and ALG does not significantly improve outcome after liver transplantation when compared with standard induction with tacrolimus and steroids: results of a prospective, randomized trial. | 2000 | Transplantation | pmid:10868638 |
| Miller J et al. | Safety and efficacy of tacrolimus in combination with mycophenolate mofetil (MMF) in cadaveric renal transplant recipients. FK506/MMF Dose-Ranging Kidney Transplant Study Group. | 2000 | Transplantation | pmid:10755543 |
| Mohamed MA et al. | TGF-beta expression in renal transplant biopsies: a comparative study between cyclosporin-A and tacrolimus. | 2000 | Transplantation | pmid:10755567 |
| Guthery SL et al. | Determination of risk factors for Epstein-Barr virus-associated posttransplant lymphoproliferative disorder in pediatric liver transplant recipients using objective case ascertainment. | 2003 | Transplantation | pmid:12698085 |
| Wang X et al. | Immunosuppression with a combination of pg490-88 and a subtherapeutic dose of FK506 in a canine renal allograft model. | 2005 | Transplantation | pmid:15940043 |
| Shapiro R et al. | Tacrolimus in pediatric renal transplantation. | 1996 | Transplantation | pmid:8990356 |
| Przepiorka D et al. | Allogeneic transplantation for advanced leukemia: improved short-term outcome with blood stem cell grafts and tacrolimus. | 1996 | Transplantation | pmid:8990368 |
| Holländer GA et al. | Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. | 1994 | Transplantation | pmid:7526495 |
| Gruessner RW et al. | A multicenter analysis of the first experience with FK506 for induction and rescue therapy after pancreas transplantation. | 1996 | Transplantation | pmid:8600635 |
| Chan L et al. | Optimal everolimus concentration is associated with risk reduction for acute rejection in de novo renal transplant recipients. | 2010 | Transplantation | pmid:20517177 |