Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen YH et al. | [Nephrotoxicity of tacrolimus and preventive effect of diltiazem: experiment with rats]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:19595068 |
Lu AW et al. | [Dual, triple, and quadruple oral tacrolimus-based immunosuppression regimens after orthotopic liver transplantation: a randomised comparative study of regimens]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:17313848 |
Li YX et al. | [Preliminary experience with partial tolerance protocol in small bowel transplantation]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:20137270 |
Feng HY et al. | [Therapeutic efficacy and safety of tacrolimus for intractable myasthenia gravis: a report of 36 patients]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22333101 |
Chen H et al. | [Mycophenolate mofetil in treatment of graft-versus-host disease after allogeneic hematopoietic cell transplantation: analysis of 44 cases]. | 2008 | Zhonghua Yi Xue Za Zhi | pmid:19080474 |
Zhao SM et al. | [Promotion of in vitro long term expansion of primitive multipotential hematopoietic cells by transduced JAK2 gene]. | 2004 | Zhonghua Yi Xue Za Zhi | pmid:15329285 |
Wang J and Fan H | [Assessment of P70S6 kinase phosphorylation after liver transplantation by phospho-flow cytometry]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25623311 |
Xia WL et al. | [Effects of ciclosporin and tacrolimus on replication of hepatitis B virus in vitro: a comparative study]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16620716 |
Lü DC et al. | [Effect of FK506 on axonal regeneration of rat sciatic nerve in regeneration chamber: an experimental study]. | 2005 | Zhonghua Yi Xue Za Zhi | pmid:16313776 |
Zhang WG et al. | [Favorable effect of chitosan sustained-release FK506 incorporated conduits on axonal regeneration in rat sciatic nerve]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16784713 |