Thomson AW et al. |
FK 506, cardiac transplantation, and graft-vessel disease. |
1992 |
Lancet |
pmid:1370563
|
First MR |
Transplantation in the nineties. |
1992 |
Transplantation |
pmid:1370734
|
Naito M et al. |
Reversal of multidrug resistance by an immunosuppressive agent FK-506. |
1992 |
Cancer Chemother. Pharmacol. |
pmid:1370765
|
Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Bishop DK and Li W |
Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. |
1992 |
J. Immunol. |
pmid:1371128
|
Hatfield SM and Roehm NW |
Cyclosporine and FK506 inhibition of murine mast cell cytokine production. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1371158
|
Metcalfe S et al. |
FK506 and rapamycin: differential sensitivity of human, baboon, cynomolgus monkey, dog and pig lymphocytes. |
1992 |
Transpl. Int. |
pmid:14621863
|
|
Japanese study of kidney transplantation: 1. Results of early phase II study. |
1992 |
Transpl. Int. |
pmid:14621866
|
|
Japanese study of FK 506 on kidney transplantation: 2. Follow-up study of FK 506-treated patients. |
1992 |
Transpl. Int. |
pmid:14621874
|
Walpoth B et al. |
Prevention of cardiac allograft rejection by FK506 and rapamycin: assessment by histology and nuclear magnetic resonance. |
1992 |
Transpl. Int. |
pmid:14621877
|
Asako H et al. |
Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules. |
1992 |
Transplantation |
pmid:1384191
|
Doi R et al. |
Effects of FK506 on exocrine pancreas in rats. |
1992 |
Pancreas |
pmid:1372739
|
Kawano K et al. |
FK 506 ameliorates normothermic liver ischemia in rats by suppressing production of tumor necrosis factor. |
1992 |
Transpl. Int. |
pmid:14621904
|
Furukawa H et al. |
The effect of bile duct ligation and bile diversion on FK506 pharmacokinetics in dogs. |
1992 |
Transplantation |
pmid:1373531
|
Sakr M et al. |
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients. |
1992 |
Transplantation |
pmid:1373535
|
Hirano Y et al. |
Morphological and functional changes of islets of Langerhans in FK506-treated rats. |
1992 |
Transplantation |
pmid:1373536
|
Takahara S et al. |
The in vitro immunosuppressive effect of deoxymethylspergualin in man as compared with FK506 and cyclosporine. |
1992 |
Transplantation |
pmid:1373537
|
Johnson MC et al. |
QT prolongation and Torsades de Pointes after administration of FK506. |
1992 |
Transplantation |
pmid:1373538
|
Kim YI et al. |
Stimulation of liver regeneration by pretreatment with azathioprine as well as cyclosporine and FK506. |
1992 |
Transplantation |
pmid:1373539
|
Carobbi A et al. |
Synergism of splenectomy and immunosuppressive drugs in prolongation of cardiac xenograft survival. |
1992 |
Transplant. Proc. |
pmid:1373543
|
Ueno M et al. |
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1373546
|
Matsuzaki T et al. |
Liver transplantation for diethylnitrosamine-induced hepatocellular carcinoma in rats. |
1992 |
Transplant. Proc. |
pmid:1373547
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Liu J et al. |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. |
1992 |
Biochemistry |
pmid:1373650
|
Adachi A et al. |
Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. |
1992 |
Intern. Med. |
pmid:1373661
|
Yamada K et al. |
New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: the relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney. |
1992 |
Transpl. Int. |
pmid:14621878
|
Meingassner JG and Stütz A |
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases? |
1992 |
J. Invest. Dermatol. |
pmid:1375617
|
Schneck FX et al. |
Pediatric renal transplantation under FK-506 immunosuppression. |
1992 |
J. Urol. |
pmid:1375663
|
Connelly PR and Thomson JA |
Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1375751
|
Lancaster JR et al. |
EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft. |
1992 |
J. Biol. Chem. |
pmid:1375934
|
Hirai T et al. |
The immunosuppressive effect of FK 506 on canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1375967
|
Tai PK et al. |
Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex. |
1992 |
Science |
pmid:1376003
|
Jegasothy BV et al. |
Tacrolimus (FK 506)--a new therapeutic agent for severe recalcitrant psoriasis. |
1992 |
Arch Dermatol |
pmid:1376102
|
Wiederrecht G et al. |
Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1376117
|
Bernstein L and Daviss SR |
Organic anxiety disorder with symptoms of akathisia in a patient treated with the immunosuppressant FK506. |
1992 |
Gen Hosp Psychiatry |
pmid:1376291
|
Hatfield SM et al. |
Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1376361
|
Ericzon BG et al. |
The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. |
1992 |
Transplantation |
pmid:1376501
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Yasunami Y et al. |
Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. |
1992 |
Transplant. Proc. |
pmid:1376510
|
Kai N et al. |
A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. |
1992 |
Transplant. Proc. |
pmid:1376511
|
Clipstone NA and Crabtree GR |
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. |
1992 |
Nature |
pmid:1377362
|
Hasegawa S et al. |
Combination use of suboptimal dose of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1279319
|
Peattie DA et al. |
Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1279700
|
Lhoëst G et al. |
Isolation and mass spectrometric identification of two metabolites of FK 506 from rat liver microsomal incubation media. |
1992 |
Pharm Acta Helv |
pmid:1279730
|
Benigni A et al. |
The acute effect of FK506 and cyclosporine on endothelial cell function and renal vascular resistance. |
1992 |
Transplantation |
pmid:1279848
|
Mor E et al. |
Late-onset acute rejection in orthotopic liver transplantation--associated risk factors and outcome. |
1992 |
Transplantation |
pmid:1279849
|
Hirano Y et al. |
The effects of FK506 and cyclosporine on the exocrine function of the rat pancreas. |
1992 |
Transplantation |
pmid:1279850
|
Takaya S et al. |
Liver transplantation in positive cytotoxic crossmatch cases using FK506, high-dose steroids, and prostaglandin E1. |
1992 |
Transplantation |
pmid:1279851
|
Partaledis JA et al. |
Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. |
1992 |
Yeast |
pmid:1279908
|
Ozawa K et al. |
An appraisal of pediatric liver transplantation from living relatives. Initial clinical experiences in 20 pediatric liver transplantations from living relatives as donors. |
1992 |
Ann. Surg. |
pmid:1280074
|
Akutsu I et al. |
[Inhibitory effects of cyclosporin A and FK-506 on eosinophil chemotactic factor activity in culture supernatants of mononuclear cells from asthmatics]. |
1992 |
Arerugi |
pmid:1280086
|
Bergstrand H and Lundquist B |
Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. |
1992 |
Allergy |
pmid:1280915
|
Barry JM |
Immunosuppressive drugs in renal transplantation. A review of the regimens. |
1992 |
Drugs |
pmid:1281071
|
Stiff DD et al. |
Metabolism of FK 506 in differentially induced rat liver microsomes. |
1992 |
Res. Commun. Chem. Pathol. Pharmacol. |
pmid:1281332
|
Min DI et al. |
Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. |
1992 |
Am J Hosp Pharm |
pmid:1282779
|
Mochizuki M |
[Immunotherapy in ocular diseases]. |
1992 |
Nippon Ganka Gakkai Zasshi |
pmid:1283052
|
Olejniczak ET et al. |
A 4D HCCH-TOCSY experiment for assigning the side chain 1H and 13C resonances of proteins. |
1992 |
J. Biomol. NMR |
pmid:1283353
|
Bauer S et al. |
The effect of the new immunosuppressive drug FK506 on the formation of secondary metabolites of cyclosporin A. |
1992 |
Int J Clin Pharmacol Ther Toxicol |
pmid:1283385
|
Renoir JM et al. |
[Effect of immunosuppressants FK506 and rapamycin on the function of progesterone receptor: protein "p59-HBI", intersection between immunology and endocrinology?]. |
1992 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:1284044
|
Natazuka T |
FK506 reverses adriamycin resistance in a multidrug-resistant human leukemia cell line. |
1992 |
Kobe J Med Sci |
pmid:1284834
|
Tocci MJ and Sigal NH |
Recent advances in the mechanism of action of cyclosporine and FK506. |
1992 |
Curr. Opin. Nephrol. Hypertens. |
pmid:1285380
|
Bavandi A et al. |
Diet-induced dermatitis response of hairless rats to systemic treatment with cyclosporin A (Sandimmun), cyclosporin H and FK506. |
1992 |
Exp. Dermatol. |
pmid:1285411
|
High KP and Handschumacher RE |
Immunity, microbial pathogenesis, and immunophilins: finding the keys, now where are the locks? |
1992 |
Infect Agents Dis |
pmid:1285413
|
Akutsu I et al. |
[Inhibitory effect of inhaled FK-506 on increased bronchial responsiveness and eosinophil infiltration in the airway mucosa]. |
1992 |
Arerugi |
pmid:1377905
|
Takaori K et al. |
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. |
1992 |
Biotherapy |
pmid:1377926
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Takai K et al. |
Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. |
1992 |
Thymus |
pmid:1378235
|
Dutz JP et al. |
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. |
1992 |
Int. Immunol. |
pmid:1378297
|
Cai X et al. |
Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. |
1992 |
Transplant. Proc. |
pmid:1379759
|
Taki J et al. |
DNA analysis of peripheral blood mononuclear cells for early detection of hepatic graft rejection. |
1992 |
Transplant. Proc. |
pmid:1379760
|
Sato Y et al. |
FK 506 suppresses class II antigen expression in regenerating livers following partial hepatectomy in the rat. |
1992 |
Transplant. Proc. |
pmid:1379761
|
Stütz A |
Immunosuppressive macrolides. |
1992 |
Transplant. Proc. |
pmid:1379762
|
Leiva MC and Lyttle CR |
Leukocyte chemotactic activity of FKBP and inhibition by FK506. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1379802
|
Iwasaki K et al. |
Effect of repeated oral doses of a novel immunosuppressive macrolide lactone on hepatic mixed-function oxidase system in the rat. Comparative study with ciclosporin. |
1992 |
Arzneimittelforschung |
pmid:1379812
|
Takada K et al. |
Distribution kinetics of FK-506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A. |
1992 |
Biopharm Drug Dispos |
pmid:1379839
|
Kahan BD |
Cyclosporin A, FK506, rapamycin: the use of a quantitative analytic tool to discriminate immunosuppressive drug interactions. |
1992 |
J. Am. Soc. Nephrol. |
pmid:1379841
|
Lauerma AI et al. |
Inhibition of contact allergy reactions by topical FK506. |
1992 |
Lancet |
pmid:1380111
|
Steiner JP et al. |
High brain densities of the immunophilin FKBP colocalized with calcineurin. |
1992 |
Nature |
pmid:1380130
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Nielsen JB et al. |
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380159
|
Calvo V et al. |
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380162
|
Takahashi N |
[Cyclophilin and FK506-binding protein]. |
1992 |
Seikagaku |
pmid:1381737
|
Lee TK et al. |
Mucosal glutamine utilization after small-bowel transplantation: an electrophysiologic study. |
1992 |
J. Surg. Res. |
pmid:1382152
|
Kaye RE et al. |
Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1382293
|
Edalji R et al. |
High-level expression of recombinant human FK-binding protein from a fusion precursor. |
1992 |
J. Protein Chem. |
pmid:1382438
|
Thomson AW and Starzl TE |
FK 506 and autoimmune disease: perspective and prospects. |
1992 |
Autoimmunity |
pmid:1382646
|
Christians U et al. |
Specific and sensitive measurement of FK506 and its metabolites in blood and urine of liver-graft recipients. |
1992 |
Clin. Chem. |
pmid:1382896
|
Fruman DA et al. |
Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. |
1992 |
Eur. J. Immunol. |
pmid:1382988
|
Mittrücker HW and Fleischer B |
Functional localization of an exocytosis-triggering G-protein in human cytotoxic T lymphocytes. |
1992 |
Immunology |
pmid:1383135
|
Yasutomi D et al. |
Inhibition of programmed cell death by cyclosporin A; preferential blocking of cell death induced by signals via TCR/CD3 complex and its mode of action. |
1992 |
Immunology |
pmid:1383138
|
Ruff VA et al. |
Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody. |
1992 |
J. Biol. Chem. |
pmid:1383222
|
Wiederrecht G et al. |
Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex. |
1992 |
J. Biol. Chem. |
pmid:1383226
|
Morris RE |
Immunopharmacology of new xenobiotic immunosuppressive molecules. |
1992 |
Semin. Nephrol. |
pmid:1384096
|
Hendey B et al. |
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. |
1992 |
Science |
pmid:1384129
|
Roberti I et al. |
Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1384182
|
Xu RX et al. |
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants. |
1992 |
FEBS Lett. |
pmid:1377648
|
Petros AM et al. |
NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein. |
1992 |
J. Med. Chem. |
pmid:1377749
|
Strom TB |
Molecular immunology and immunopharmacology of allograft rejection. |
1992 |
Kidney Int. Suppl. |
pmid:1383599
|
Wang SC et al. |
FK-506 inhibits proliferation and IL-4 messenger RNA production by a T-helper 2 cell line. |
1992 |
J. Surg. Res. |
pmid:1383612
|