tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Anemia, Hemolytic D000743 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Pemphigoid, Benign Mucous Membrane D010390 4 associated lipids
Confusion D003221 4 associated lipids
Parotitis D010309 4 associated lipids
Osteoporosis, Postmenopausal D015663 4 associated lipids
Hearing Loss, Noise-Induced D006317 4 associated lipids
Arthritis, Reactive D016918 3 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Meningococcal Infections D008589 3 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Lichen Planus D008010 3 associated lipids
Intestinal Atresia D007409 3 associated lipids
Toxocariasis D014120 3 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Leukoencephalopathies D056784 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Paronychia D010304 3 associated lipids
Gingivitis D005891 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Luchowska E et al. FK506 attenuates 1-methyl-4-phenylpyridinium- and 3-nitropropionic acid-evoked inhibition of kynurenic acid synthesis in rat cortical slices. 2003 Acta Neurobiol Exp (Wars) pmid:12926536
Ishikawa Y et al. Search for novel gene markers of traumatic brain injury by time differential microarray analysis. 2006 Acta Neurochir. Suppl. pmid:16671447
Uchino H et al. Calcineurin and cyclophilin D are differential targets of neuroprotection by immunosuppressants CsA and FK506 in ischemic brain damage. 2003 Acta Neurochir. Suppl. pmid:14753416
Katsura KI et al. FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors. 2003 Acta Neurochir. Suppl. pmid:14753417
Mitsui T et al. The effects of FK506 on refractory inflammatory myopathies. 2011 Acta Neurol Belg pmid:22141281
Ogul H et al. Severe toxic leukoencephalopathy associated with tacrolimus after living donor liver transplantation. 2015 Acta Neurol Belg pmid:24854146
Miura S et al. Combined treatment with prednisolone and tacrolimus for myasthenia gravis with invasive thymoma. 2010 Acta Neurol Belg pmid:20514937
Kortekangas-Savolainen O and Kiilholma P Treatment of vulvovaginal erosive and stenosing lichen planus by surgical dilatation and methotrexate. 2007 Acta Obstet Gynecol Scand pmid:17364310
Jongen VH et al. Vaginal delivery after lung transplantation. 2000 Acta Obstet Gynecol Scand pmid:11130101
Helgesen AL et al. Vaginal involvement in genital erosive lichen planus. 2010 Acta Obstet Gynecol Scand pmid:20583940