Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mrowietz U et al. | The novel ascomycin derivative SDZ ASM 981 is effective for psoriasis when used topically under occlusion. | 1998 | Br. J. Dermatol. | pmid:9990361 |
Hebert MF et al. | Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers. | 1999 | J Clin Pharmacol | pmid:9987705 |
Nakahama H et al. | Effect of a novel immunosuppressant, FK 506, on autoimmune glomerulonephritis in Brown Norway rats. | 1999 | Nephron | pmid:9933758 |
Hebebrand D et al. | [Genetic methods in experimental xenogenic nerve transplantation]. | 1998 | Langenbecks Arch Chir Suppl Kongressbd | pmid:9931858 |
Takeda Y et al. | Mechanisms of FK 506-induced hypertension in the rat. | 1999 | Hypertension | pmid:9931093 |
Al-Nasser IA | In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506. | 1998 | Toxicology | pmid:9928632 |
Honoré P et al. | [Liver transplantation: experiences and results of a program at the University of Liege]. | 1998 | Rev Med Liege | pmid:9927867 |
Cai Q et al. | Reduction of infarct size in isolated rat heart by CsA and FK506: possible role of phosphatase inhibition. | 1998 | Cardiovasc Drugs Ther | pmid:9926283 |
Wingard JR et al. | Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. | 1998 | Biol. Blood Marrow Transplant. | pmid:9923414 |
Yoshida A et al. | Studies of repeated administration of FK-506 on myocardial metabolism in rats. | 1998 | J Toxicol Sci | pmid:9922943 |