tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Srinivas NR Letter: sublingual dosing of tacrolimus in transplant patients-interesting concept to overcome first pass effects. 2017 Aliment. Pharmacol. Ther. pmid:28589592
Benítez C et al. Letter: sublingual dosing of tacrolimus in transplant patients-interesting concept to overcome first pass effects. Authors' reply. 2017 Aliment. Pharmacol. Ther. pmid:28589580
Yamamoto S et al. Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis. 2008 Aliment. Pharmacol. Ther. pmid:18549460
O'Leary JG Editorial: tacrolimus-how low can you go? 2017 Aliment. Pharmacol. Ther. pmid:28589579
Solari S et al. Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation: a pilot study. 2017 Aliment. Pharmacol. Ther. pmid:28261844
Hoshino H et al. Effects of FK506 on an experimental model of colitis in rats. 1995 Aliment. Pharmacol. Ther. pmid:7544633
Ortiz de Frutos FJ [New horizons in the treatment of atopic dermatitis]. Allergol Immunopathol (Madr) pmid:11988144
Mori F et al. Increase of natural killer cells in children with liver transplantation-acquired food allergy. Allergol Immunopathol (Madr) pmid:29456038
Regueiro-García A et al. Haploidentical stem cell transplantation in a boy with chronic granulomatous disease. Allergol Immunopathol (Madr) pmid:29373243
Inoue Y et al. Food allergy after cord blood stem cell transplantation with tacrolimus therapy in two patients who developed veno-occlusive disease. 2012 Allergol Int pmid:22722810
Tsuji T et al. Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice. 2016 Allergol Int pmid:26666476
Miyachi Y et al. Suplatast/tacrolimus combination therapy for refractory facial erythema in adult patients with atopic dermatitis: a meta-analysis study. 2007 Allergol Int pmid:17582208
Ebihara N et al. Blood level of tacrolimus in patients with severe allergic conjunctivitis treated by 0.1% tacrolimus ophthalmic suspension. 2012 Allergol Int pmid:22361511
Yamamoto M et al. A novel atopic dermatitis model induced by topical application with dermatophagoides farinae extract in NC/Nga mice. 2007 Allergol Int pmid:17460441
Wollenberg A et al. Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. 2008 Allergy pmid:18445188
Jensen JM et al. Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis. 2012 Allergy pmid:22142306
Bieber T et al. Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis. 2007 Allergy pmid:17298428
Kaufmann R et al. Onset of pruritus relief with pimecrolimus cream 1% in adult patients with atopic dermatitis: a randomized trial. 2006 Allergy pmid:16436149
Oldhoff JM et al. Modulation of the atopy patch test: tacrolimus 0.1% compared with triamcinolone acetonide 0.1%. 2006 Allergy pmid:16629794
Simon D et al. Inflammatory cell numbers and cytokine expression in atopic dermatitis after topical pimecrolimus treatment. 2005 Allergy pmid:15932386