Kuo CJ et al. |
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. |
1992 |
Nature |
pmid:1614535
|
Strasser S et al. |
Effect of FK506 on insulin secretion in normal dogs. |
1992 |
Metab. Clin. Exp. |
pmid:1371575
|
Andersson J et al. |
FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro. |
1992 |
Transplant. Proc. |
pmid:1371621
|
Matsuura T et al. |
Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro. |
1992 |
Transplant. Proc. |
pmid:1371623
|
Moutabarrik A et al. |
In vitro FK506 kidney tubular cell toxicity. |
1992 |
Transpl. Int. |
pmid:14621743
|
Okamura N et al. |
Enhanced liver regeneration by FK 506 can be blocked by interleukin-1 alpha and interleukin-2. |
1992 |
Transplant. Proc. |
pmid:1371624
|
Moutabarrik A et al. |
FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells. |
1992 |
Transpl. Int. |
pmid:14621744
|
Sakr M et al. |
Effect of renal ischemia on plasma levels of FK 506 in rats. |
1992 |
Transplant. Proc. |
pmid:1371625
|
Stangl MJ et al. |
The use of FK506 and RS61443 for reversal of small-bowel rejection. |
1992 |
Transpl. Int. |
pmid:14621800
|
Kusne S et al. |
Infections during a randomized trial comparing cyclosporine to FK 506 immunosuppression in liver transplantation. |
1992 |
Transplant. Proc. |
pmid:1371626
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Lee C et al. |
FK-506 binding protein from Tolypocladium inflatum: resistance of FKBP/FK-506 complex against proteolysis. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1371677
|
Hung DT and Schreiber SL |
cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1374240
|
Jayaraman T et al. |
FK506 binding protein associated with the calcium release channel (ryanodine receptor). |
1992 |
J. Biol. Chem. |
pmid:1374404
|
Höllsberg P et al. |
Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. |
1992 |
J. Immunol. |
pmid:1374452
|
Schreiber SL and Crabtree GR |
The mechanism of action of cyclosporin A and FK506. |
1992 |
Immunol. Today |
pmid:1374612
|
Demetris AJ et al. |
Conversion of liver allograft recipients from cyclosporine to FK506 immunosuppressive therapy--a clinicopathologic study of 96 patients. |
1992 |
Transplantation |
pmid:1374944
|
Bundick RV et al. |
FK506 as an agonist to induce inhibition of interleukin 2 production. |
1992 |
Transplantation |
pmid:1374947
|
Sakr M et al. |
The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats. |
1992 |
Transplantation |
pmid:1374948
|
Lepre CA et al. |
Solution structure of FK506 bound to FKBP-12. |
1992 |
FEBS Lett. |
pmid:1375171
|
Hatazawa C et al. |
Effect of FK 506 on bowel transplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376517
|
Jain A et al. |
Intravenous, oral pharmacokinetics, and oral dosing of FK 506 in small bowel transplant patients. |
1992 |
Transplant. Proc. |
pmid:1376518
|
Masutani H et al. |
Suppression of the histologic changes of GVHD by FK 506 in rat small bowel transplantation. |
1992 |
Transplant. Proc. |
pmid:1376519
|
Santiago SF et al. |
Effect of short-term immunosuppressive therapy with FK 506 or CyA on the donor in small intestine allotransplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376520
|
Utsunomiya H et al. |
Effect of FK 506 on orthotopic small bowel transplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376521
|
Yagihashi A et al. |
Changes in cell surface markers in human small bowel transplantation with FK 506. |
1992 |
Transplant. Proc. |
pmid:1376522
|
Abu-Elmagd K et al. |
Management of intestinal transplantation in humans. |
1992 |
Transplant. Proc. |
pmid:1376523
|
Kobayashi M et al. |
Posttransplant donor-specific T-lymphocytotoxic antibody in liver transplant patients with a positive crossmatch. |
1992 |
Transplant. Proc. |
pmid:1281570
|
Lemster B et al. |
Cytokine gene expression in murine lymphocytes activated in the presence of FK 506, bredinin, mycophenolic acid, or brequinar sodium. |
1992 |
Transplant. Proc. |
pmid:1281576
|
Tze WJ et al. |
FK 506: an effective immunosuppressant for islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1281577
|
Kamei T et al. |
Established intraportal islet allograft is rejected despite the acceptance of donor-specific second cardiac allograft. |
1992 |
Transplant. Proc. |
pmid:1281579
|
Woo J et al. |
FK 506 treatment following syngeneic bone marrow transplantation does not inhibit clonal deletion of V beta 5+ or V beta 11+ T cells. |
1992 |
Transplant. Proc. |
pmid:1281583
|
Souza ER et al. |
Acute effects of FK 506 on glomerular hemodynamics. |
1992 |
Transplant. Proc. |
pmid:1281585
|
Hanke JH et al. |
FK506 and rapamycin selectively enhance degradation of IL-2 and GM-CSF mRNA. |
1992 |
Lymphokine Cytokine Res. |
pmid:1281674
|
Thomson AW |
The spectrum of action of new immunosuppressive drugs. |
1992 |
Clin. Exp. Immunol. |
pmid:1379130
|
Fischer G et al. |
Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity. |
1992 |
Mol. Microbiol. |
pmid:1379319
|
Rondeau E |
[Mechanism of action of the new immunosuppressants: cyclosporin A, FK 506 and rapamycin]. |
1992 |
Nephrologie |
pmid:1379348
|
Schreiber SL |
Immunophilin-sensitive protein phosphatase action in cell signaling pathways. |
1992 |
Cell |
pmid:1379518
|
Aldape RA et al. |
Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex. |
1992 |
J. Biol. Chem. |
pmid:1379588
|
Langrehr JM et al. |
Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat. |
1992 |
J. Clin. Invest. |
pmid:1379617
|
Kumano K et al. |
[Functional and morphological changes in rat kidney induced by FK506 and its reversal by various vasodilators]. |
1992 |
Nippon Hinyokika Gakkai Zasshi |
pmid:1379657
|
Woodle ES et al. |
FK506: inhibition of humoral mechanisms of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1379749
|
Walpoth B et al. |
Assessment of new immunosuppressive drugs in a rat cardiac allograft heterotopic model. |
1992 |
Eur Surg Res |
pmid:1380460
|
Petros AM et al. |
Conformation of two non-immunosuppressive FK506 analogs when bound to FKBP by isotope-filtered NMR. |
1992 |
FEBS Lett. |
pmid:1380470
|
Van Thiel DH et al. |
FK 506 reduces the injury experienced following renal ischemia and reperfusion. |
1992 |
Ren Fail |
pmid:1380720
|
Bolton C |
The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). |
1992 |
Agents Actions |
pmid:1380765
|
Terada N et al. |
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1380801
|
Friccius H et al. |
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. |
1992 |
Int. J. Immunopharmacol. |
pmid:1380951
|
Dumont FJ et al. |
The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin. |
1992 |
J. Exp. Med. |
pmid:1380976
|
Wakabayashi H et al. |
Effect of FK 506 and cyclosporine A on hepatic energy status in the rat after warm ischemia, as monitored by 31P nuclear magnetic resonance spectroscopy in vivo. |
1992 |
Transplant. Proc. |
pmid:1384205
|
Griffin AD et al. |
FK 506 in canine renal transplantation. |
1992 |
Transplant. Proc. |
pmid:1384209
|
Griffiths RJ et al. |
Characterisation of passively transferred antigen arthritis induced by methylated bovine serum albumin in the rat: effect of FK 506 on arthritis development. |
1992 |
Agents Actions |
pmid:1384284
|
Todo S et al. |
Intestinal transplantation in composite visceral grafts or alone. |
1992 |
Ann. Surg. |
pmid:1384443
|
Massol N et al. |
Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1384470
|
Siekierka JJ and Sigal NH |
FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond. |
1992 |
Curr. Opin. Immunol. |
pmid:1384551
|
Hultsch T et al. |
The effect of the immunophilin ligands rapamycin and FK506 on proliferation of mast cells and other hematopoietic cell lines. |
1992 |
Mol. Biol. Cell |
pmid:1384815
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Doi R et al. |
Biochemical characterization of the effects of FK506 on signal transduction in exocytotic function of rat pancreatic acini. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7679738
|
Gunji Y et al. |
Pathologic characteristics of vasculitis in renal transplant recipient dogs receiving immunosuppressive agents, FK 506, rapamycin, or RS-61443. |
1993 |
Transplant. Proc. |
pmid:7679841
|
Gregory CR et al. |
Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo. |
1993 |
Transplant. Proc. |
pmid:7679842
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors. |
1993 |
Transplant. Proc. |
pmid:7679843
|
Reese JC et al. |
The effect of FK506 on canine bile flow. |
1993 |
Transplantation |
pmid:7504342
|
Woodle ES et al. |
FK506--reversal of humorally mediated cardiac allograft rejection in the presence of preformed anti-class I antibody. |
1993 |
Transplantation |
pmid:7504346
|
Jindal RM et al. |
Effect of deoxyspergualin on the endocrine function of the rat pancreas. |
1993 |
Transplantation |
pmid:7504347
|
Nishinaka Y et al. |
Protective effect of FK506 on ischemia/reperfusion-induced myocardial damage in canine heart. |
1993 |
J. Cardiovasc. Pharmacol. |
pmid:7681507
|
Luan S et al. |
Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7681590
|
Doi R et al. |
Structural and functional changes of exocrine pancreas induced by FK506 in rats. |
1993 |
Gastroenterology |
pmid:7681795
|
Simek SL et al. |
Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. |
1993 |
Genomics |
pmid:7507077
|
Quesniaux VF |
Immunosuppressants: tools to investigate the physiological role of cytokines. |
1993 |
Bioessays |
pmid:7507316
|
Hill CC et al. |
Penile prosthesis surgery in the immunosuppressed patient. |
1993 |
Transplantation |
pmid:7692633
|
Roberts JP et al. |
Reversal of chronic rejection after treatment failure with FK506 and RS61443. |
1993 |
Transplantation |
pmid:7692634
|
Storb R et al. |
FK-506 and methotrexate prevent graft-versus-host disease in dogs given 9.2 Gy total body irradiation and marrow grafts from unrelated dog leukocyte antigen-nonidentical donors. |
1993 |
Transplantation |
pmid:7692635
|
McDiarmid SV et al. |
A comparison of renal function in cyclosporine- and FK-506-treated patients after primary orthotopic liver transplantation. |
1993 |
Transplantation |
pmid:7692636
|
Sato M et al. |
FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. |
1993 |
Acta Endocrinol. |
pmid:7509103
|
Clipstone NA and Crabtree GR |
Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509131
|
Takahara S |
Efficacy of FK506 in renal transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509132
|
Textor SC et al. |
Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. |
1993 |
Transplantation |
pmid:7685934
|
Denesyuk AI et al. |
Structural similarity of the binding sites of cyclophilin A-cyclosporin A and FKBP-FK506 systems. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7683466
|
Waschulewski IH et al. |
Effects of the immunosuppressants cyclosporin A and FK 506 on exocytosis in the rat exocrine pancreas in vitro. |
1993 |
Br. J. Pharmacol. |
pmid:7683567
|
Ohtake M et al. |
Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506. |
1993 |
Gastroenterol. Jpn. |
pmid:7683616
|
Murphy MP and Morris RE |
Brequinar sodium effectively and potently suppresses allograft rejection in a heterotopic mouse heart transplant model. |
1993 |
Transplant. Proc. |
pmid:7685955
|
Li W and Handschumacher RE |
Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin. |
1993 |
J. Biol. Chem. |
pmid:7686148
|
Wong PY et al. |
Recurrence of primary biliary cirrhosis after liver transplantation following FK506-based immunosuppression. |
1993 |
J. Hepatol. |
pmid:7686192
|
Sakr MF et al. |
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion. |
1993 |
J. Hepatol. |
pmid:7686193
|
Henke W and Jung K |
Comparison of the effects of the immunosuppressive agents FK 506 and cyclosporin A on rat kidney mitochondria. |
1993 |
Biochem. Pharmacol. |
pmid:7690566
|
Jacobs JC et al. |
Pyoderma gangrenosum in infancy. |
1993 |
J. Am. Acad. Dermatol. |
pmid:7688775
|
Garrity GM et al. |
Genetic relationships among actinomycetes that produce the immunosuppressant macrolides FK506, FK520/FK523 and rapamycin. |
1993 |
J. Ind. Microbiol. |
pmid:7688970
|
Hoof T et al. |
Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin. |
1993 |
Eur. J. Pharmacol. |
pmid:7689059
|
Lieberman R |
FK506, artificial intelligence and pharmacoeconomics. |
1993 |
J Clin Pharmacol |
pmid:7690045
|
McMichael J et al. |
An intelligent and cost-effective computer dosing system for individualizing FK506 therapy in transplantation and autoimmune disorders. |
1993 |
J Clin Pharmacol |
pmid:7690046
|
Jain AB et al. |
Pharmacokinetics of FK506 in liver transplant recipients after continuous intravenous infusion. |
1993 |
J Clin Pharmacol |
pmid:7690047
|
Langrehr JM et al. |
Clinical course, morphology, and treatment of chronically rejecting small bowel allografts. |
1993 |
Transplantation |
pmid:7679526
|
Uemoto S et al. |
Experience with FK506 in living-related liver transplantation. |
1993 |
Transplantation |
pmid:7679528
|
Talento A et al. |
A single administration of LFA-1 antibody confers prolonged allograft survival. |
1993 |
Transplantation |
pmid:7679531
|