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A yeast chemical genetics approach identifies the compound 3,4,5-trimethoxybenzyl isothiocyanate as a calcineurin inhibitor. |
2014 |
FEBS Lett. |
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Is minimal, [almost] steroid-free immunosuppression a safe approach in adult liver transplantation? Long-term outcome of a prospective, double blind, placebo-controlled, randomized, investigator-driven study. |
2014 |
Ann. Surg. |
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Wu Y et al. |
Increased macrophage activation inhibited by tacrolimus in the kidney of diabetic rats. |
2014 |
Nephron Exp. Nephrol. |
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Sirolimus and mTOR inhibitors in liver transplantation: the wheel has come full circle. |
2014 |
Am. J. Transplant. |
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Catalano G et al. |
Everolimus-based immunosuppression in a case of ABO-incompatible liver transplantation with calcineurin inhibitor-related posterior occipital syndrome. |
2014 |
Transpl. Int. |
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Clinical significance of peripheral blood lymphocyte sensitivity to glucocorticoids for the differentiation of high-risk patients with decreased allograft function after glucocorticoid withdrawal in renal transplantation. |
2014 |
Clin Ther |
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Chemometric methods for the quantification of crystalline tacrolimus in solid dispersion by powder X-ray diffractrometry. |
2014 |
J Pharm Sci |
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Calcineurin inhibitors suppress the high-temperature stress sensitivity of the yeast ubiquitin ligase Rsp5 mutant: a new method of screening for calcineurin inhibitors. |
2014 |
FEMS Yeast Res. |
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Goldberg NR et al. |
Success with single-agent immunosuppression for multifocal choroidopathies. |
2014 |
Am. J. Ophthalmol. |
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Pulsipher MA et al. |
The addition of sirolimus to tacrolimus/methotrexate GVHD prophylaxis in children with ALL: a phase 3 Children's Oncology Group/Pediatric Blood and Marrow Transplant Consortium trial. |
2014 |
Blood |
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Impact of single immunosuppressive drug withdrawal on lymphocyte immunoreactivity. |
2014 |
J. Surg. Res. |
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Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus. |
2014 |
Transl Res |
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Calcineurin activity assay measurement by liquid chromatography-tandem mass spectrometry in the multiple reaction monitoring mode. |
2014 |
Clin. Chem. |
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Effect of different tacrolimus levels on early outcomes after kidney transplantation. |
2014 |
Ann. Transplant. |
pmid:24509826
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Xie M et al. |
Tacrolimus-related seizure after pediatric liver transplantation--a single-center experience. |
2014 |
Pediatr Transplant |
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Balato A et al. |
Tacrolimus does not alter the production of several cytokines and antimicrobial peptide in Malassezia furfur-infected-keratinocytes. |
2014 |
Mycoses |
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Qin XL et al. |
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus. |
2014 |
Drug Metab. Dispos. |
pmid:24195812
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Li CJ et al. |
Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipients. |
2014 |
PLoS ONE |
pmid:24465960
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Silva-Cunha A et al. |
Evaluation of the pharmacokinetics and ocular tolerance of a microemulsion containing tacrolimus. |
2014 |
J Ocul Pharmacol Ther |
pmid:24199740
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Asrani SK et al. |
De novo sirolimus and reduced-dose tacrolimus versus standard-dose tacrolimus after liver transplantation: the 2000-2003 phase II prospective randomized trial. |
2014 |
Am. J. Transplant. |
pmid:24456026
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Oellerich M et al. |
Use of graft-derived cell-free DNA as an organ integrity biomarker to reexamine effective tacrolimus trough concentrations after liver transplantation. |
2014 |
Ther Drug Monit |
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Pharmacogenomic implications of population admixture: Brazil as a model case. |
2014 |
Pharmacogenomics |
pmid:24444410
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Kurzawski M et al. |
CYP3A5 and CYP3A4, but not ABCB1 polymorphisms affect tacrolimus dose-adjusted trough concentrations in kidney transplant recipients. |
2014 |
Pharmacogenomics |
pmid:24444408
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Hidradenitis suppurativa after renal transplantation: complete remission after switching from oral cyclosporine to oral tacrolimus. |
2014 |
J. Am. Acad. Dermatol. |
pmid:25437996
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Khorrami A et al. |
Tacrolimus ameliorates functional disturbances and oxidative stress in isoproterenol-induced myocardial infarction. |
2014 |
Daru |
pmid:25312839
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Chen YK et al. |
Personalized tacrolimus dose requirement by CYP3A5 but not ABCB1 or ACE genotyping in both recipient and donor after pediatric liver transplantation. |
2014 |
PLoS ONE |
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Clinical outcome in heart transplant recipients receiving everolimus in combination with dosage reduction of the calcineurin inhibitor cyclosporine A or tacrolimus. |
2014 |
Transpl. Immunol. |
pmid:24932812
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Zhu X et al. |
Pilot study using tacrolimus rather than cyclosporine plus antithymocyte globulin as an immunosuppressive therapy regimen option for severe aplastic anemia in adults. |
2014 |
Blood Cells Mol. Dis. |
pmid:24931461
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Han N et al. |
Population pharmacokinetic-pharmacogenetic model of tacrolimus in the early period after kidney transplantation. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
pmid:24238261
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Taguchi K et al. |
False tacrolimus concentrations measured by antibody-conjugated magnetic immunoassay in liver transplant patient: 2 case reports and literature review. |
2014 |
Exp Clin Transplant |
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Cho A et al. |
Calcineurin signaling regulates neural induction through antagonizing the BMP pathway. |
2014 |
Neuron |
pmid:24698271
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[Atopic dermatitis in pregnancy]. |
2014 |
Arerugi |
pmid:24714179
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Rangel EB |
Tacrolimus in pancreas transplant: a focus on toxicity, diabetogenic effect and drug-drug interactions. |
2014 |
Expert Opin Drug Metab Toxicol |
pmid:25255841
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Casey MJ et al. |
Prolonged immunosuppression preserves nonsensitization status after kidney transplant failure. |
2014 |
Transplantation |
pmid:24717218
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Everolimus in liver transplantation. |
2014 |
Curr Opin Organ Transplant |
pmid:25254569
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Lower variability in 24-hour exposure during once-daily compared to twice-daily tacrolimus formulation in kidney transplantation. |
2014 |
Transplantation |
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Impact of CYP3A5 genetic polymorphisms on the pharmacokinetics and short-term remission in patients with ulcerative colitis treated with tacrolimus. |
2014 |
J. Gastroenterol. Hepatol. |
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Dose conversion factor between cyclosporine and tacrolimus in pediatric heart transplant recipients. |
2014 |
J. Heart Lung Transplant. |
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Tacrolimus abrogates TGF-β1-induced type I collagen production in normal human fibroblasts through suppressing p38MAPK signalling pathway: implications on treatment of chronic atopic dermatitis lesions. |
2014 |
J Eur Acad Dermatol Venereol |
pmid:23301526
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Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases: a prospective multicenter trial. |
2014 |
Biol. Blood Marrow Transplant. |
pmid:25196857
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Ghanem RC et al. |
Tacrolimus for the treatment of subepithelial infiltrates resistant to topical steroids after adenoviral keratoconjunctivitis. |
2014 |
Cornea |
pmid:25188789
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Ricciardelli I et al. |
Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells. |
2014 |
Blood |
pmid:25185261
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Conversion from tacrolimus to belatacept to prevent the progression of chronic kidney disease in pancreas transplantation: case report of two patients. |
2014 |
Am. J. Transplant. |
pmid:25179306
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Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. |
2014 |
Clin. Pharmacol. Ther. |
pmid:24126681
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Carcas-Sansuán AJ et al. |
Conversion from Prograf to Advagraf in stable paediatric renal transplant patients and 1-year follow-up. |
2014 |
Pediatr. Nephrol. |
pmid:23907143
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Chatterjea A et al. |
Suppression of the immune system as a critical step for bone formation from allogeneic osteoprogenitors implanted in rats. |
2014 |
J. Cell. Mol. Med. |
pmid:24237965
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Mabe S et al. |
Detecting protein-protein interactions based on kinase-mediated growth induction of mammalian cells. |
2014 |
Sci Rep |
pmid:25135216
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Protein degradation by ubiquitin-proteasome system in formation and labilization of contextual conditioning memory. |
2014 |
Learn. Mem. |
pmid:25135196
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Tacrolimus-induced left ventricular apical hypertrophy in a patient with post-allogeneic hematopoietic stem cell transplantation. |
2014 |
Int. J. Cardiol. |
pmid:25131917
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Expression profiles of genes involved in xenobiotic metabolism and disposition in human renal tissues and renal cell models. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:25036895
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ZivÄić-Ćosić S et al. |
Immune reactivity of renal transplant recipients receiving interleukin-2 receptor antagonists during the early posttransplant period. |
2014 |
Int Urol Nephrol |
pmid:23515930
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Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats. |
2014 |
J Ethnopharmacol |
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Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population. |
2014 |
BMC Res Notes |
pmid:24593903
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Bao J and Liang H |
Tacrolimus-induced permanent asymptomatic pontine myelinolysis after liver transplantation. |
2014 |
Intern. Med. |
pmid:25088893
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Yan YH et al. |
Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization. |
2014 |
Neurosci. Lett. |
pmid:24607931
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Purani JM and Purani HJ |
Treatment of geographic tongue with topical tacrolimus. |
2014 |
BMJ Case Rep |
pmid:25085945
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A randomized phase II trial of tacrolimus, mycophenolate mofetil and sirolimus after non-myeloablative unrelated donor transplantation. |
2014 |
Haematologica |
pmid:25085357
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Sethna CB and Gipson DS |
Treatment of FSGS in Children. |
2014 |
Adv Chronic Kidney Dis |
pmid:24602468
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Demmers MW et al. |
Substantial proliferation of human renal tubular epithelial cell-reactive CD4+CD28null memory T cells, which is resistant to tacrolimus and everolimus. |
2014 |
Transplantation |
pmid:24157471
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Angioimmunoblastic T cell lymphoma: an unusual presentation of posttransplant lymphoproliferative disorder in a pediatric patient. |
2014 |
Acta Haematol. |
pmid:24157860
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Calcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation. |
2014 |
Eur. Respir. J. |
pmid:23645405
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Thapa RK and Yoo BK |
Evaluation of the effect of tacrolimus-loaded liquid crystalline nanoparticles on psoriasis-like skin inflammation. |
2014 |
J Dermatolog Treat |
pmid:23210668
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Viecelli A et al. |
Diagnostic and management dilemma of a pancreas-kidney transplant recipient with aplastic anaemia. |
2014 |
BMJ Case Rep |
pmid:25257886
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Efficacy and safety of systemic tacrolimus in high-risk penetrating keratoplasty after graft failure with systemic cyclosporine. |
2014 |
Cornea |
pmid:25255133
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Segarra-Medrano A et al. |
Evolution of antibody titre against the M-type phospholipase A2 receptor and clinical response in idiopathic membranous nephropathy patients treated with tacrolimus. |
2014 |
Nefrologia |
pmid:25036063
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Boschetti G et al. |
Tacrolimus induction followed by maintenance monotherapy is useful in selected patients with moderate-to-severe ulcerative colitis refractory to prior treatment. |
2014 |
Dig Liver Dis |
pmid:25023007
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John K et al. |
Role of dendritic cells in the context of acute cellular rejection: comparison between tacrolimus- or cyclosporine A-treated heart transplanted recipients. |
2014 |
Cytometry B Clin Cytom |
pmid:24668729
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Okamoto T et al. |
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with febrile urinary tract infection. |
2014 |
Eur. J. Pediatr. |
pmid:24221606
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Steinebrunner N et al. |
Reduced residual gene expression of nuclear factor of activated T cells-regulated genes correlates with the risk of cytomegalovirus infection after liver transplantation. |
2014 |
Transpl Infect Dis |
pmid:24666466
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Levinger E et al. |
Topical 0.03% tacrolimus for subepithelial infiltrates secondary to adenoviral keratoconjunctivitis. |
2014 |
Graefes Arch. Clin. Exp. Ophthalmol. |
pmid:24696044
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Nikitin AV |
[Mechanisms of nephrotoxic action of immunodepressants, calcineurine inhibitors]. |
2014 |
Antibiot. Khimioter. |
pmid:25051716
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[Effect of tacrolimus on the results of living related kidney donor transplantation]. |
2014 |
Ter. Arkh. |
pmid:25095659
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Shilpa PS et al. |
Topical tacrolimus in the management of oral lichen planus: literature review. |
2014 |
J Calif Dent Assoc |
pmid:25080722
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Kuramitsu S et al. |
[Case report of introducing MMF and steroids as an immunosuppressive therapy after living-donor liver transplantation for a patient with the diabetic nephropathy]. |
2014 |
Fukuoka Igaku Zasshi |
pmid:25000660
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Kluk J et al. |
Follicular mucinosis treated with topical 0.1% tacrolimus ointment. |
2014 |
Clin. Exp. Dermatol. |
pmid:24252117
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[Perioperative agranulocytosis induced by immunosuppressants in a renal graft recipient : a case report]. |
2014 |
Hinyokika Kiyo |
pmid:25001642
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Friedrich RB et al. |
Nanoencapsulation of tacrolimus in lipid-core nanocapsules showed similar immunosuppressive activity after oral and intraperitoneal administrations. |
2014 |
J Biomed Nanotechnol |
pmid:25016659
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Mai S et al. |
In vitro and in vivo release characteristics of Tacrolimus (FK506) from an episcleral drug-delivery implant. |
2014 |
J Ocul Pharmacol Ther |
pmid:24933028
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Nomura H et al. |
A patient with lupus miliaris disseminatus faciei treated successfully with a combination of oral metronidazole and topical tacrolimus. |
2014 |
J. Dermatol. |
pmid:24931738
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Rahman Z et al. |
Near-infrared and fourier transform infrared chemometric methods for the quantification of crystalline tacrolimus from sustained-release amorphous solid dispersion. |
2014 |
J Pharm Sci |
pmid:24931728
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Kim SH et al. |
Expression, purification and characterization of soluble recombinant peptidyl-prolyl cis/trans isomerase from Vibrio anguillarum. |
2014 |
Protein Expr. Purif. |
pmid:24931498
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Liu Z et al. |
Tacrolimus-based versus cyclosporine-based immunosuppression in hepatitis C virus-infected patients after liver transplantation: a meta-analysis and systematic review. |
2014 |
PLoS ONE |
pmid:25198195
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Tran D et al. |
Conversion from twice-daily to once-daily extended-release tacrolimus in renal transplant recipients: 2-year results and review of the literature. |
2014 |
Exp Clin Transplant |
pmid:24844288
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Feng S et al. |
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells. |
2014 |
Angew. Chem. Int. Ed. Engl. |
pmid:24841150
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Kahvecioglu S et al. |
Effects of calcineurin inhibitors on paraoxonase and arylesterase activity after a kidney transplant. |
2014 |
Exp Clin Transplant |
pmid:24447269
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Doren EL and Aya-ay ML |
Pyoderma gangrenosum following breast reduction: treatment with topical tacrolimus and steroids. |
2014 |
Aesthet Surg J |
pmid:24448967
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Lin YH and Pratt MR |
A dual small-molecule rheostat for precise control of protein concentration in Mammalian cells. |
2014 |
Chembiochem |
pmid:24615791
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Mita A et al. |
Optimal initial dose of orally administered once-daily extended-release tacrolimus following intravenous tacrolimus therapy after liver transplantation. |
2014 |
Transplant. Proc. |
pmid:24767351
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Hashi S et al. |
Assessment of four methodologies (microparticle enzyme immunoassay, chemiluminescent enzyme immunoassay, affinity column-mediated immunoassay, and flow injection assay-tandem mass spectrometry) for measuring tacrolimus blood concentration in Japanese liver transplant recipients. |
2014 |
Transplant. Proc. |
pmid:24767342
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Uemoto S et al. |
Safety and efficacy of once-daily modified-release tacrolimus in liver transplant recipients: a multicenter postmarketing surveillance in Japan. |
2014 |
Transplant. Proc. |
pmid:24767340
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Yamanaka M et al. |
Development and evaluation of a tacrolimus cream formulation using a binary solvent system. |
2014 |
Int J Pharm |
pmid:24456671
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Levy G et al. |
REFINE: a randomized trial comparing cyclosporine A and tacrolimus on fibrosis after liver transplantation for hepatitis C. |
2014 |
Am. J. Transplant. |
pmid:24456049
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Upadhyay V et al. |
Rapid and sensitive UPLC-MS-MS determination of tacrolimus in Wistar rats and human blood. |
2014 |
J Chromatogr Sci |
pmid:23264321
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DÃaz-GarcÃa C et al. |
Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth trajectory. |
2014 |
Fertil. Steril. |
pmid:25439799
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Tsunashima D et al. |
Assessment of tacrolimus absorption from the human intestinal tract: open-label, randomized, 4-way crossover study. |
2014 |
Clin Ther |
pmid:24680768
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Ibrahim O et al. |
The role of infliximab in the treatment of superficial granulomatous pyoderma of the head and neck. |
2014 |
J. Am. Acad. Dermatol. |
pmid:25438004
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Kraaij MD et al. |
Human monocytes produce interferon-gamma upon stimulation with LPS. |
2014 |
Cytokine |
pmid:24680476
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Sawamoto K et al. |
Mechanisms of lower maintenance dose of tacrolimus in obese patients. |
2014 |
Drug Metab. Pharmacokinet. |
pmid:24670405
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Xie M et al. |
Brucellosis infection in an adult liver transplant recipient. |
2014 |
Transpl Infect Dis |
pmid:24666385
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Takazono T et al. |
Paradoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report. |
2014 |
BMC Infect. Dis. |
pmid:24576098
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