tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Latent Tuberculosis D055985 1 associated lipids
Invasive Pulmonary Aspergillosis D055744 1 associated lipids
Keratosis, Actinic D055623 3 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Pancreatitis, Graft D055589 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Primary Graft Dysfunction D055031 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Dendritic Cell Sarcoma, Interdigitating D054739 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Huh KH et al. De novo low-dose sirolimus versus mycophenolate mofetil in combination with extended-release tacrolimus in kidney transplant recipients: a multicentre, open-label, randomized, controlled, non-inferiority trial. 2017 Nephrol. Dial. Transplant. pmid:28810721
Lloberas N et al. The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. 2017 Pharmacogenet. Genomics pmid:28704257
Ruiz S et al. Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology. 2017 Hum. Mol. Genet. pmid:28973643
Damon C et al. Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening. 2017 Am. J. Transplant. pmid:27597269
Gooptu M and Koreth J Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? 2017 Haematologica pmid:28458253
Chiasson VL et al. Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. 2017 Hypertension pmid:28584011
Shoda W et al. Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. 2017 Kidney Int. pmid:28341239
Zhang X et al. Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. 2017 Dis. Markers pmid:28246425
Mashayekhi S et al. The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. 2017 Br. J. Dermatol. pmid:28244087
D'Avola D et al. Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. 2017 Liver Transpl. pmid:28160394
Kaneshiro S et al. The efficacy and safety of additional administration of tacrolimus in patients with rheumatoid arthritis who showed an inadequate response to tocilizumab. 2017 Mod Rheumatol pmid:27181115
Andreu F et al. A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. 2017 Clin Pharmacokinet pmid:28050888
Shimizu K Development of New Liposome Targeting Strategies for Application of Disease Therapies. 2017 Yakugaku Zasshi pmid:28049894
Maneechote C et al. Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. 2017 J. Cell. Mol. Med. pmid:28941171
Shrestha BM Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences. 2017 Exp Clin Transplant pmid:27938316
Yu MY et al. Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study. 2017 PLoS ONE pmid:29155873
Gonzalez-Andrades M et al. Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. 2017 Eye Contact Lens pmid:26222098
Olmedo Martín RV et al. Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. 2017 Rev Esp Enferm Dig pmid:28617029
Yagi S et al. New-onset diabetes mellitus after living-donor liver transplantation: association with graft synthetic function. 2017 Surg. Today pmid:27837276
Pietrosi G and Chinnici C Report on Liver Cell Transplantation Using Human Fetal Liver Cells. 2017 Methods Mol. Biol. pmid:27830561