|
FK-506 shows similar graft survival rate to cyclosporine but fewer side effects: Pitt transplant team. |
1991 |
Nephrol News Issues |
pmid:1720511
|
Ito T et al. |
The mechanism of tolerance induced by a perioperative injection of bone marrow cells and a brief course of FK 506. |
1991 |
Transplant. Proc. |
pmid:1703716
|
|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
|
First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Ochiai T et al. |
Effective and safe use of FK 506: combination treatment with rapamycin or RS-61443 in experimental organ transplantation. |
1991 |
Transplant. Proc. |
pmid:1721255
|
Siekierka JJ et al. |
Potential roles of other FK 506-binding proteins in mediating the effects of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721256
|
Morris RE |
In vivo immunopharmacology of the macrolides FK 506 and rapamycin: toward the era of rational immunosuppressive drug discovery, development, and use. |
1991 |
Transplant. Proc. |
pmid:1721257
|
Habucky K et al. |
The pharmacodynamics of pentobarbital following FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721282
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Francavilla A et al. |
The effects of FK 506, cyclosporine, and rapamycin on liver growth in vitro and in vivo. |
1991 |
Transplant. Proc. |
pmid:1721287
|
Blanc P et al. |
Antiproliferative effect of FK 506 and cyclosporine on adult human hepatocytes in culture. |
1991 |
Transplant. Proc. |
pmid:1721288
|
Loréal O et al. |
FK 506 is less cytotoxic than cyclosporine to human and rat hepatocytes in vitro. |
1991 |
Transplant. Proc. |
pmid:1721289
|
McCarthy SA et al. |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes. |
1991 |
Transplant. Proc. |
pmid:1721314
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721315
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Woo J et al. |
Effects of FK 506, mycophenolic acid, and bredinin on OKT-3-, PMA-, and alloantigen-induced activation molecule expression on cultured CD4+ and CD8+ human lymphocytes. |
1991 |
Transplant. Proc. |
pmid:1721319
|
Chen-Woan M et al. |
Diminished lymphocyte growth from endomyocardial biopsies from cardiac transplant patients on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721320
|
Fukuzawa M et al. |
Effect of FK 506 on CD4+ and CD8+ T-cell function in vivo. |
1991 |
Transplant. Proc. |
pmid:1721321
|
Nakamura K et al. |
The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis. |
1991 |
Transplant. Proc. |
pmid:1721346
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
Felser I et al. |
Changes in quality of life following conversion from CyA to FK 506 in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721350
|
Schreiber SL |
Chemistry and biology of the immunophilins and their immunosuppressive ligands. |
1991 |
Science |
pmid:1702904
|
Alessiani M et al. |
CMV infection in liver transplantation under cyclosporine or FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721351
|
Wasik M et al. |
Effect of FK506 versus cyclosporine on human natural and antibody-dependent cytotoxicity reactions in vitro. |
1991 |
Transplantation |
pmid:1702910
|
Green M et al. |
Infectious complications of pediatric liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721352
|
Carroll PB et al. |
Effect of the immunosuppressant FK506 on glucose-induced insulin secretion from adult rat islets of Langerhans. |
1991 |
Transplantation |
pmid:1702911
|
Torre-Cisneros J et al. |
The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721353
|
Starzl TE et al. |
Hepatotrophic effects of FK506 in dogs. |
1991 |
Transplantation |
pmid:1702912
|
Perico N et al. |
FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. |
1991 |
Transplant. Proc. |
pmid:1721378
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Wagner K et al. |
Effect of FK 506 on excretion of urinary enzymes in rats. |
1991 |
Transplant. Proc. |
pmid:1721379
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Moutabarrik A et al. |
In vitro FK 506 kidney tubular cell toxicity. |
1991 |
Transplant. Proc. |
pmid:1721383
|
McCauley J et al. |
Changes in renal function after liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721385
|
Tauxe WN et al. |
A comparison of the renal effects (ERPF, GFR, and FF) of FK 506 and cyclosporine in patients with liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721386
|
Tai J et al. |
In vivo and in vitro effect of FK 506 on rat Leydig cell function. |
1991 |
Transplant. Proc. |
pmid:1721409
|
Ricordi C et al. |
Human islet allotransplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721410
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
Yamashita T et al. |
Prolongation of pancreaticoduodenal allograft survival in rats by treatment with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721414
|
Fukuzaki T et al. |
Induction of tolerance to islet allografts with preoperative donor spleen cell injection and a short course of FK 506 treatment. |
1991 |
Transplant. Proc. |
pmid:1721415
|
Tzakis AG et al. |
FK 506 rescue in chronic graft-versus-host-disease after bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721416
|
Ziccardi VB et al. |
Maxillofacial considerations in orthotopic liver transplantation. |
1991 |
Oral Surg. Oral Med. Oral Pathol. |
pmid:1704494
|
Bierer BE et al. |
The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. |
1991 |
Eur. J. Immunol. |
pmid:1705513
|
Heitman J et al. |
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1705713
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
Griffiths EJ and Halestrap AP |
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin. |
1991 |
Biochem. J. |
pmid:1706598
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721441
|
Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
|
Lin CY et al. |
Effects of FK 506 on the biochemical markers in canine lung allograft rejection. |
1991 |
Transplant. Proc. |
pmid:1721445
|
Propper DJ et al. |
Evidence that FK 506 may abrogate suppressor cell activity induced by blood transfusion. |
1991 |
Transplant. Proc. |
pmid:1721446
|
Fabrega AJ et al. |
FK 506 enhances the beneficial effects of donor-specific blood transfusion on allograft survival in rats. |
1991 |
Transplant. Proc. |
pmid:1721447
|
Davies CB et al. |
Effects of donor-specific transfusion, cyclosporine A and FK 506 on rat cardiac allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721448
|
Sigal NH et al. |
Inhibition of human T-cell activation by FK 506, rapamycin, and cyclosporine A. |
1991 |
Transplant. Proc. |
pmid:1712132
|
Fung JJ et al. |
Current status of FK 506 in liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1712133
|
Francavilla A et al. |
Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506. |
1991 |
Hepatology |
pmid:1712337
|
Aoki H |
[FK 506, a new immunosuppressant produced by a Streptomyces]. |
1991 |
Nippon Rinsho |
pmid:1712403
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Miyahara H et al. |
Comparative studies of the effects of FK506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. |
1991 |
Clin. Immunol. Immunopathol. |
pmid:1712688
|
McAlpine JB et al. |
Revised NMR assignments for rapamycin. |
1991 |
J. Antibiot. |
pmid:1712766
|
Banerji SS et al. |
The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. |
1991 |
Mol. Cell. Biol. |
pmid:1712901
|
Chen MF et al. |
The influence of FK-506 on the thymus and spleen in normal C3H/He mice: flow cytometric analysis of lymphocyte subpopulations. |
1991 |
Immunol. Lett. |
pmid:1722778
|
Sakai K et al. |
The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents. |
1991 |
Brain Res. |
pmid:1723023
|
Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
|
Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Nielsen JB et al. |
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. |
1991 |
Biochemistry |
pmid:2043618
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
|
FK 506--an investigational immunosuppressant. |
1991 |
Med Lett Drugs Ther |
pmid:1716722
|
Ochiai T et al. |
[Immunosuppressive agents--advances of the developmental studies and the mode of action]. |
1991 |
Nippon Rinsho |
pmid:1715926
|
Ricordi C et al. |
In vivo effect of FK506 on human pancreatic islets. |
1991 |
Transplantation |
pmid:1716797
|
Katz IA et al. |
Comparison of the effects of FK506 and cyclosporine on bone mineral metabolism in the rat. A pilot study. |
1991 |
Transplantation |
pmid:1716801
|
Liu J et al. |
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. |
1991 |
Cell |
pmid:1715244
|
Henderson DJ et al. |
Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production. |
1991 |
Immunology |
pmid:1715317
|
DeFranco AL |
Signal transduction. Immunosuppressants at work. |
1991 |
Nature |
pmid:1715515
|
Flanagan WM et al. |
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. |
1991 |
Nature |
pmid:1715516
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|
Pourtier-Manzanedo A et al. |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro. |
1991 |
Anticancer Drugs |
pmid:1724925
|
Nakahama H et al. |
Comparative effects of cyclosporine A and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1725322
|