tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Abu-Elmagd K et al. | Hepatic and intestinal transplantation at the University of Pittsburgh. | 1998 | Clin Transpl | pmid:10503105 |
| Yoshimura R et al. | The effect of immunosuppressive agents (FK-506, rapamycin) on renal P450 systems in rat models. | 1999 | J. Pharm. Pharmacol. | pmid:10504034 |
| Linder MW and Elin RJ | Implications of methodologic bias for therapeutic drug monitoring. | 1999 | Arch. Pathol. Lab. Med. | pmid:10506447 |
| Letko E et al. | Tacrolimus (FK 506). | 1999 | Ann. Allergy Asthma Immunol. | pmid:10507260 |
| Cacciarelli TV et al. | An analysis of pretransplantation variables associated with long-term allograft outcome in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy. | 1999 | Transplantation | pmid:10507484 |
| Cao Z et al. | Comparison of tacrolimus concentrations measured by the IMx tacrolimus II vs the PRO-TRAC II FK506 ELISA assays. | 1999 | Clin. Chem. | pmid:10508139 |
| Tredger JM et al. | Performance of the IMx tacrolimus II assay and practical limits of detection. | 1999 | Clin. Chem. | pmid:10508145 |
| Chautan M et al. | Interdigital cell death can occur through a necrotic and caspase-independent pathway. | 1999 | Curr. Biol. | pmid:10508592 |
| Sche PP et al. | Display cloning: functional identification of natural product receptors using cDNA-phage display. | 1999 | Chem. Biol. | pmid:10508685 |
| Lee WP and Mathes DW | Hand transplantation: pertinent data and future outlook. | 1999 | J Hand Surg Am | pmid:10509267 |
| Böttiger Y et al. | Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. | 1999 | Br J Clin Pharmacol | pmid:10510159 |
| Dusting GJ et al. | Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms. | 1999 | Br. J. Pharmacol. | pmid:10510443 |
| Robinson BV et al. | Optimal dosing of intravenous tacrolimus following pediatric heart transplantation. | 1999 | J. Heart Lung Transplant. | pmid:10512526 |
| Rostaing L et al. | Differences in Type 1 and Type 2 intracytoplasmic cytokines, detected by flow cytometry, according to immunosuppression (cyclosporine A vs. tacrolimus) in stable renal allograft recipients. | 1999 | Clin Transplant | pmid:10515221 |
| Charney DA et al. | Plasma cell-rich acute renal allograft rejection. | 1999 | Transplantation | pmid:10515379 |
| Fan L et al. | Improved artificial death switches based on caspases and FADD. | 1999 | Hum. Gene Ther. | pmid:10515447 |
| Cunningham EB | An inositolphosphate-binding immunophilin, IPBP12. | 1999 | Blood | pmid:10515881 |
| Cardenas ME et al. | Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action. | 1999 | Clin. Microbiol. Rev. | pmid:10515904 |
| Moore JM | NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery. | 1999 | Biopolymers | pmid:10516573 |
| Przepiorka D et al. | Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after HLA-mismatched marrow or blood stem cell transplantation. | 1999 | Bone Marrow Transplant. | pmid:10516680 |