tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morello RJ et al. | Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice. | 2016 | Acta Cir Bras | pmid:27828601 |
| Lee YJ et al. | Acquired Bilateral Dyspigmentation on Face and Neck: Clinically Appropriate Approaches. | 2016 | J. Korean Med. Sci. | pmid:27822947 |
| Khan S et al. | Tacrolimus-loaded nanostructured lipid carriers for oral delivery - Optimization of production and characterization. | 2016 | Eur J Pharm Biopharm | pmid:27449630 |
| Siponen M et al. | Cathepsin K expression is increased in oral lichen planus. | 2016 | J. Oral Pathol. Med. | pmid:27152719 |
| Tomei P et al. | Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation. | 2016 | J. Nephrol. | pmid:27026415 |
| Chitvanich S et al. | Combination of non-ablative fractional photothermolysis and 0.1% tacrolimus ointment is efficacious for treating idiopathic guttate hypomelanosis. | 2016 | J Dermatolog Treat | pmid:26864301 |
| Klein OR et al. | Alternative-Donor Hematopoietic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide for Nonmalignant Disorders. | 2016 | Biol. Blood Marrow Transplant. | pmid:26860634 |
| Kanda Y et al. | A randomized controlled trial of cyclosporine and tacrolimus with strict control of blood concentrations after unrelated bone marrow transplantation. | 2016 | Bone Marrow Transplant. | pmid:26437063 |
| Ishida H et al. | A Prospective Randomized, Comparative Trial of High-Dose Mizoribine Versus Mycophenolate Mofetil in Combination With Tacrolimus and Basiliximab for Living Donor Renal Transplant: A Multicenter Trial. | 2016 | Exp Clin Transplant | pmid:27733107 |
| Tsunashima D et al. | Preparation of extended release solid dispersion formulations of tacrolimus using ethylcellulose and hydroxypropylmethylcellulose by solvent evaporation method. | 2016 | J. Pharm. Pharmacol. | pmid:26773717 |
| Mok MM et al. | Acute Phosphate Nephropathy: An Under-Recognized Complication Leading to Impaired Allograft Function After Renal Transplant. | 2016 | Nephrology (Carlton) | pmid:27730726 |
| Kim JM et al. | Immunosuppression status of liver transplant recipients with hepatitis C affects biopsy-proven acute rejection. | 2016 | Clin Mol Hepatol | pmid:27729628 |
| Bogossian H et al. | Expression of NO Synthase Under Medication with Cyclosporine A, Mycophenolate Mofetil, and Tacrolimus during Development of Transplant Vasculopathy on Rat Cardiac Allograft. | 2016 | Cardiovasc Ther | pmid:26924260 |
| Treister N et al. | An Open-Label Phase II Randomized Trial of Topical Dexamethasone and Tacrolimus Solutions for the Treatment of Oral Chronic Graft-versus-Host Disease. | 2016 | Biol. Blood Marrow Transplant. | pmid:27590106 |
| Jun H et al. | Clinical advantages including medication adherence with conversion to once-daily advagraf and sirolimus combination in stable kidney recipients. | 2016 | Int J Clin Pharmacol Ther | pmid:26709601 |
| Schmutz JL | [No increased risk of cancer under pimecrolimus]. | 2016 | Ann Dermatol Venereol | pmid:26708204 |
| Valbuena H et al. | Comparing the effect of isotopically labeled or structural analog internal standards on the performance of a LC-MS/MS method to determine ciclosporin A, everolimus, sirolimus and tacrolimus in whole blood. | 2016 | Clin. Chem. Lab. Med. | pmid:26351941 |
| Kronbichler A et al. | Moderator's view: The use of calcineurin inhibitors in the treatment of lupus nephritis. | 2016 | Nephrol. Dial. Transplant. | pmid:27591329 |
| Tamaki M et al. | Fungal meningitis caused by Lomentospora prolificans after allogeneic hematopoietic stem cell transplantation. | 2016 | Transpl Infect Dis | pmid:27258644 |
| Wang L et al. | Therapeutic advances for primary biliary cholangitis: the old and the new. | 2016 | Eur J Gastroenterol Hepatol | pmid:26862931 |
| Ben Fredj N et al. | Modeling of Tacrolimus Exposure in Kidney Transplant According to Posttransplant Time Based on Routine Trough Concentration Data. | 2016 | Exp Clin Transplant | pmid:27506258 |
| Miyata Y et al. | Pharmacokinetics of a Once-Daily Dose of Tacrolimus Early After Liver Transplantation: With Special Reference to CYP3A5 and ABCB1 Single Nucleotide Polymorphisms. | 2016 | Ann. Transplant. | pmid:27503662 |
| Yaowakulpatana K et al. | Impact of CYP3A5 polymorphism on trough concentrations and outcomes of tacrolimus minimization during the early period after kidney transplantation. | 2016 | Eur. J. Clin. Pharmacol. | pmid:26635230 |
| Griffin SP and Nelson JE | Impact of a Clinical Solid Organ Transplant Pharmacist on Tacrolimus Nephrotoxicity, Therapeutic Drug Monitoring, and Institutional Revenue Generation in Adult Kidney Transplant Recipients. | 2016 | Prog Transplant | pmid:27628498 |
| Faraj W et al. | Osteoporosis in Pediatric Liver Transplantation. | 2016 | Prog Transplant | pmid:27555069 |
| Saliba F et al. | Corticosteroid-Sparing and Optimization of Mycophenolic Acid Exposure in Liver Transplant Recipients Receiving Mycophenolate Mofetil and Tacrolimus: A Randomized, Multicenter Study. | 2016 | Transplantation | pmid:27454919 |
| Liu XX et al. | Limited Sampling Strategy for the Estimation of Tacrolimus Area Under the Concentration-Time Curve in Chinese Adult Liver Transplant Patients. | 2016 | Pharmacology | pmid:27449772 |
| Chan SW et al. | Associations of the CYP3A5*3 and CYP3A4*1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese. | 2016 | J Clin Pharm Ther | pmid:27511886 |
| Zhao CY et al. | External evaluation of published population pharmacokinetic models of tacrolimus in adult renal transplant recipients. | 2016 | Br J Clin Pharmacol | pmid:26574188 |
| Seo J et al. | Therapeutic advantage of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmonary fibrosis mouse model. | 2016 | Pulm Pharmacol Ther | pmid:26768967 |
| Zhang X et al. | The effect of calcineurin inhibitors in the induction and maintenance treatment of lupus nephritis: a systematic review and meta-analysis. | 2016 | Int Urol Nephrol | pmid:26781720 |
| Ayyala RS et al. | Imaging findings in a child with calcineurin inhibitor-induced pain syndrome after bone marrow transplant for beta thalassemia major. | 2016 | Pediatr Radiol | pmid:27324395 |
| Luo X et al. | Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. | 2016 | Acta Pharmacol. Sin. | pmid:26924289 |
| Miura K et al. | Development of the Intestinal Transplantation Model With Major Histocompatibility Complex Inbred CLAWN Miniature Swine. | 2016 | Transplant. Proc. | pmid:27320612 |
| Lien YH | Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. | 2016 | Am. J. Med. | pmid:26714210 |
| Miura M et al. | Inter-laboratory Variability of Current Immunoassay Methods for Tacrolimus among Japanese Hospitals. | 2016 | Biol. Pharm. Bull. | pmid:27263473 |
| Weiner SM | [Combination of tacrolimus and MMF for treatment of proliferative lupus nephritis]. | 2016 | Z Rheumatol | pmid:27259912 |
| Gaynor JJ et al. | Lower tacrolimus trough levels are associated with subsequently higher acute rejection risk during the first 12 months after kidney transplantation. | 2016 | Transpl. Int. | pmid:26442829 |
| Hannun P et al. | Efficacy and Safety of Elective Conversion From Sotrastaurin (STN) to Tacrolimus (TAC) or Mycophenolate (MPS) in Stable Kidney Transplant Recipients. | 2016 | Ther Drug Monit | pmid:26919549 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Nijhoff MF et al. | Glycemic Stability Through Islet-After-Kidney Transplantation Using an Alemtuzumab-Based Induction Regimen and Long-Term Triple-Maintenance Immunosuppression. | 2016 | Am. J. Transplant. | pmid:26288226 |
| Otte JB | Pediatric liver transplantation: Personal perspectives on historical achievements and future challenges. | 2016 | Liver Transpl. | pmid:27096329 |
| Anuradha D and Parsad | FK506 regulates pigmentation by maturing the melanosome and facilitating their transfer to keratinocytes. | 2016 | Dermatol Ther | pmid:27093927 |
| Krejci K et al. | Clinical experience of conversion from cyclosporine to tacrolimus prolonged-release in stabilized kidney transplant patients. | 2016 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:27174195 |
| Muduma G et al. | A cost-utility analysis of prolonged-release tacrolimus relative to immediate-release tacrolimus and ciclosporin in liver transplant recipients in the UK. | 2016 | J Med Econ | pmid:27172118 |
| Tariciotti L et al. | Everolimus and Advagraf Ab Initio in Combined Liver and Kidney Transplant With Donor-Specific Antibodies: A Case Report. | 2016 | Transplant. Proc. | pmid:27932158 |
| Alagoz S et al. | Gangliocytoma Presenting With Tacrolimus Neurotoxicity in a Renal Transplant Recipient: Case Report. | 2016 | Transplant. Proc. | pmid:27932167 |
| Sugitani A et al. | Unusual case of tacrolimus vascular toxicity after deceased donor renal transplantation. | 2016 | Nephrology (Carlton) | pmid:27004749 |
| Thölking G et al. | Tacrolimus Concentration/Dose Ratio is Associated with Renal Function After Liver Transplantation. | 2016 | Ann. Transplant. | pmid:27003330 |
| Oddis CV | Update on the pharmacological treatment of adult myositis. | 2016 | J. Intern. Med. | pmid:27098592 |